Detalhe da pesquisa
1.
Structural mechanism for specific binding of chemical compounds to amyloid fibrils.
Nat Chem Biol
; 19(10): 1235-1245, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37400537
2.
HOIP modulates the stability of GPx4 by linear ubiquitination.
Proc Natl Acad Sci U S A
; 119(44): e2214227119, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279464
3.
Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles.
Proc Natl Acad Sci U S A
; 117(49): 31123-31133, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229560
4.
Fluorescent Imaging of ß-Amyloid Using BODIPY Based Near-Infrared Off-On Fluorescent Probe.
Bioconjug Chem
; 29(10): 3459-3466, 2018 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30189724
5.
A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aß and ameliorating Aß-associated disorders in Alzheimer's disease transgenic mice.
RSC Med Chem
; 15(4): 1216-1224, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38665839
6.
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1.
Acta Pharm Sin B
; 14(1): 319-334, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261830
7.
Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads.
J Med Chem
; 66(4): 2608-2621, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36723914
8.
Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer.
Sci Adv
; 9(47): eadj0123, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992178
9.
Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.
J Med Chem
; 65(20): 13645-13659, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36221183
10.
Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.
Cancer Res
; 82(19): 3588-3602, 2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857807
11.
An inherently kidney-targeting near-infrared fluorophore based probe for early detection of acute kidney injury.
Biosens Bioelectron
; 172: 112756, 2021 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33197750
12.
Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol
; 28(6): 855-865.e9, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33979649
13.
Visualizing Autophagic Flux during Endothelial Injury with a Pathway-Inspired Tandem-Reaction Based Fluorogenic Probe.
Theranostics
; 9(19): 5672-5680, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31534510
14.
Direct C-H functionalization of difluoroboron dipyrromethenes (BODIPYs) at ß-position by iodonium salts.
RSC Adv
; 8(10): 5542-5549, 2018 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35542398
15.
Discovery of a novel fluorescent probe for the sensitive detection of ß-amyloid deposits.
Biosens Bioelectron
; 75: 136-41, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26313423