1.
Chem Commun (Camb)
; 56(15): 2292-2295, 2020 Feb 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31985739
RESUMO
Pd-Catalyzed enantioselective C(sp3)-H arylation of N-(o-Br-aryl) anilides has been disclosed, and quaternary α-nitro amides were constructed with up to 98% ee. The presence of the nitro group on the substrate enables the progress of the reaction and the ready transformation of the product to optically active quaternary amino acid derivatives.