Detalhe da pesquisa
1.
Harnessing non-Watson-Crick's base pairing to enhance CRISPR effectors cleavage activities and enable gene editing in mammalian cells.
Proc Natl Acad Sci U S A
; 121(2): e2308415120, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38150477
2.
Clinical progress in genome-editing technology and in vivo delivery techniques.
Trends Genet
; 39(3): 208-216, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669950
3.
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants.
Proc Natl Acad Sci U S A
; 120(52): e2311752120, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134199
4.
Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response.
Proc Natl Acad Sci U S A
; 119(34): e2207841119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969778
5.
Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis.
Proc Natl Acad Sci U S A
; 119(8)2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35173043
6.
Investigating the Cytosolic Delivery of Proteins by Lipid Nanoparticles Using the Chloroalkane Penetration Assay.
Biochemistry
; 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38334719
7.
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Nature
; 553(7687): 217-221, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29258297
8.
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33649229
9.
Lipidoid Artificial Compartments for Bidirectional Regulation of Enzyme Activity through Nanomechanical Action.
J Am Chem Soc
; 145(1): 551-559, 2023 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36537880
10.
Current Developments and Challenges of mRNA Vaccines.
Annu Rev Biomed Eng
; 24: 85-109, 2022 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35231177
11.
Developing Biodegradable Lipid Nanoparticles for Intracellular mRNA Delivery and Genome Editing.
Acc Chem Res
; 54(21): 4001-4011, 2021 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668716
12.
Engineering a Nano/Biointerface for Cell and Organ-Selective Drug Delivery.
Langmuir
; 38(30): 9092-9098, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852946
13.
Combinatorial Library of Cyclic Benzylidene Acetal-Containing pH-Responsive Lipidoid Nanoparticles for Intracellular mRNA Delivery.
Bioconjug Chem
; 31(7): 1835-1843, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32520527
14.
Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing.
Acc Chem Res
; 52(3): 665-675, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30586281
15.
Imidazole-Based Synthetic Lipidoids for Inâ Vivo mRNA Delivery into Primary T Lymphocytes.
Angew Chem Int Ed Engl
; 59(45): 20083-20089, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662132
16.
Protein and mRNA Delivery Enabled by Cholesteryl-Based Biodegradable Lipidoid Nanoparticles.
Angew Chem Int Ed Engl
; 59(35): 14957-14964, 2020 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32438474
17.
A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases.
Gene Ther
; 26(5): 187-197, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926963
18.
Nonviral Nanoparticles for CRISPR-Based Genome Editing: Is It Just a Simple Adaption of What Have Been Developed for Nucleic Acid Delivery?
Biomacromolecules
; 20(9): 3333-3339, 2019 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31342740
19.
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles.
Proc Natl Acad Sci U S A
; 113(11): 2868-73, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26929348
20.
Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice.
Int J Cancer
; 143(7): 1797-1805, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29696632