Detalhe da pesquisa
1.
Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion.
Cancer Immunol Immunother
; 72(12): 4001-4014, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37973660
2.
Reciprocal regulation of GAS5 lncRNA levels and mTOR inhibitor action in prostate cancer cells.
Prostate
; 75(7): 693-705, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650269
3.
Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells.
Pituitary
; 18(5): 674-84, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25557289
4.
Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation.
Pharmaceuticals (Basel)
; 17(2)2024 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399413
5.
The EFEMP1 gene: a frequent target for epigenetic silencing in multiple human pituitary adenoma subtypes.
Neuroendocrinology
; 98(3): 200-11, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24080855
6.
Targeting FGFRs Using PD173074 as a Novel Therapeutic Strategy in Cholangiocarcinoma.
Cancers (Basel)
; 15(9)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37173994
7.
Preclinical evidence for anaplastic lymphoma kinase inhibitors as novel therapeutic treatments for cholangiocarcinoma.
Front Oncol
; 13: 1184900, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38144528
8.
Inhibition of serine/arginine-rich protein kinase-1 (SRPK1) prevents cholangiocarcinoma cells induced angiogenesis.
Toxicol In Vitro
; 82: 105385, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568131
9.
Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts.
Cell Rep Med
; 3(6): 100541, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732148
10.
Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells.
Cancer Res Treat
; 53(2): 457-470, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33070556
11.
Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata.
Front Oncol
; 10: 547392, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33163396
12.
Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival.
Biosci Rep
; 37(4)2017 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28754805
13.
Preincubation of pituitary tumor cells with the epidrugs zebularine and trichostatin A are permissive for retinoic acid-augmented expression of the BMP-4 and D2R genes.
Endocrinology
; 154(5): 1711-21, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23539512
14.
Epigenomic silencing of the BMP-4 gene in pituitary adenomas: a potential target for epidrug-induced re-expression.
Endocrinology
; 153(8): 3603-12, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22700770
15.
The pituitary tumour epigenome: aberrations and prospects for targeted therapy.
Nat Rev Endocrinol
; 8(8): 486-94, 2012 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22525730
16.
Quantitative, genome-wide analysis of the DNA methylome in sporadic pituitary adenomas.
Endocr Relat Cancer
; 19(6): 805-16, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045325
17.
Reversal of endogenous dopamine receptor silencing in pituitary cells augments receptor-mediated apoptosis.
Endocrinology
; 152(2): 364-73, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21177832