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J Am Vet Med Assoc ; 259(11): 1332-1336, 2021 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-34727063

RESUMO

CASE DESCRIPTION: An 11-year-old sexually intact male Shih Tzu diagnosed with acute kidney injury and left-sided congestive heart failure that had nonelective mitral valve surgery. CLINICAL FINDINGS: Metabolic alkalosis developed postoperatively, and plasma bicarbonate concentration peaked 2 days after surgery (40.2 mmol/L; pH, 7.550). TREATMENT AND OUTCOME: Acetazolamide administration increased the urinary excretion of bicarbonate and contributed to the improvement of the dog's acid-base status and oxygenation capacity. Metabolic alkalosis persisted for 4 days after surgery, and no treatment was required after resolution. Plasma urea nitrogen and creatinine concentrations normalized 2 days after surgery. CLINICAL RELEVANCE: Severe metabolic alkalosis can occur as a complication following mitral valve surgery. Acetazolamide may be suitable for the treatment of severe metabolic alkalosis.


Assuntos
Injúria Renal Aguda , Alcalose , Doenças do Cão , Acetazolamida/uso terapêutico , Injúria Renal Aguda/etiologia , Injúria Renal Aguda/terapia , Injúria Renal Aguda/veterinária , Alcalose/etiologia , Alcalose/veterinária , Animais , Bicarbonatos/uso terapêutico , Doenças do Cão/tratamento farmacológico , Doenças do Cão/etiologia , Cães , Concentração de Íons de Hidrogênio , Masculino
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