Detalhe da pesquisa
1.
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes.
Cell
; 161(7): 1592-605, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26052046
2.
Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring.
Bioorg Med Chem Lett
; 23(10): 2912-5, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562056
3.
Conformational restriction approach to ß-secretase (BACE1) inhibitors III: effective investigation of the binding mode by combinational use of X-ray analysis, isothermal titration calorimetry and theoretical calculations.
Bioorg Med Chem
; 21(21): 6506-22, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24051074
4.
beta-Secretase inhibitor potency is decreased by aberrant beta-cleavage location of the "Swedish mutant" amyloid precursor protein.
J Biol Chem
; 285(3): 1634-42, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19926793
5.
Histone Deacetylase 2 Knockdown Ameliorates Morphological Abnormalities of Dendritic Branches and Spines to Improve Synaptic Plasticity in an APP/PS1 Transgenic Mouse Model.
Front Mol Neurosci
; 14: 782375, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34899185
6.
The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons.
Cell Rep
; 20(6): 1319-1334, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28793257
7.
Conformational restriction approach to ß-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode.
J Med Chem
; 55(20): 8838-58, 2012 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22998419
8.
Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner.
PLoS One
; 4(1): e4199, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19142223
9.
Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.
Biochem Biophys Res Commun
; 355(1): 41-6, 2007 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17292328