Detalhe da pesquisa
1.
In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate Chemicals.
Chem Res Toxicol
; 34(2): 507-513, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433197
2.
Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential.
Chem Res Toxicol
; 33(12): 3048-3053, 2020 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33283517
3.
Metabolic profiles for the pyrrolizidine alkaloid neopetasitenine and its metabolite petasitenine in humans extrapolated from rat in vivo and in vitro data sets using a simplified physiologically based pharmacokinetic model.
J Toxicol Sci
; 46(9): 391-399, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34470991
4.
Plasma, liver, and kidney exposures in rats after oral doses of industrial chemicals predicted using physiologically based pharmacokinetic models: A case study of perï¬uorooctane sulfonic acid.
J Toxicol Sci
; 45(12): 763-767, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268676