Detalhe da pesquisa
1.
High performance plasma amyloid-ß biomarkers for Alzheimer's disease.
Nature
; 554(7691): 249-254, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420472
2.
Size and Shape of Amyloid Fibrils Induced by Ganglioside Nanoclusters: Role of Sialyl Oligosaccharide in Fibril Formation.
Langmuir
; 33(48): 13874-13881, 2017 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29148800
3.
Retromer and Rab2-dependent trafficking mediate PS1 degradation by proteasomes in endocytic disturbance.
J Neurochem
; 137(4): 647-58, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26896628
4.
GM1 ganglioside and Alzheimer's disease.
Glycoconj J
; 32(3-4): 87-91, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25903682
5.
Influence of APOE genotype and the presence of Alzheimer's pathology on synaptic membrane lipids of human brains.
J Neurosci Res
; 92(5): 641-50, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24446209
6.
Novel plasma biomarker surrogating cerebral amyloid deposition.
Proc Jpn Acad Ser B Phys Biol Sci
; 90(9): 353-64, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391320
7.
Prevention of amyloid ß fibril deposition on the synaptic membrane in the precuneus by ganglioside nanocluster-targeting inhibitors.
RSC Chem Biol
; 5(5): 459-466, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38725912
8.
Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-ß peptide.
J Neurosci
; 32(15): 5223-36, 2012 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496568
9.
Density of GM1 in nanoclusters is a critical factor in the formation of a spherical assembly of amyloid ß-protein on synaptic plasma membranes.
Langmuir
; 29(7): 2258-64, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23294326
10.
The Double-Layered Structure of Amyloid-ß Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization.
ACS Chem Neurosci
; 14(15): 2648-2657, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37482658
11.
[Searching for biomarkers to diagnose dementia].
Nihon Rinsho
; 70(5): 785-9, 2012 May.
Artigo
em Japonês
| MEDLINE | ID: mdl-22620001
12.
[Strategy and perspectives for development of Alzheimer disease-modifying drugs].
Seishin Shinkeigaku Zasshi
; 114(3): 262-7, 2012.
Artigo
em Japonês
| MEDLINE | ID: mdl-22568060
13.
Abeta polymerization through interaction with membrane gangliosides.
Biochim Biophys Acta
; 1801(8): 868-77, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20117237
14.
Surface-induced phase separation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Abeta oligomerization.
Biochim Biophys Acta
; 1798(6): 1090-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20226163
15.
Pathological significance of ganglioside clusters in Alzheimer's disease.
J Neurochem
; 116(5): 806-12, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21214549
16.
Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease.
J Biol Chem
; 284(48): 33400-8, 2009 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679659
17.
Plasma Amyloid-ß Biomarker Associated with Cognitive Decline in Preclinical Alzheimer's Disease.
J Alzheimers Dis
; 77(3): 1057-1065, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32925048
18.
Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid beta-protein fibrillogenesis.
Biochim Biophys Acta
; 1778(12): 2717-26, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18727916
19.
Late endocytic dysfunction as a putative cause of amyloid fibril formation in Alzheimer's disease.
J Neurochem
; 109(5): 1250-60, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19317854
20.
Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3.
J Neurochem
; 110(4): 1254-62, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19549280