Change of blue light hazard and circadian effect of LED backlight displayer with color temperature and age.

In order to provide a theoretical reference for the personalized design and color temperature adjustment of LED backlight displayer, the spectral distribution of the LED backlight displayer at different color temperatures (1200-6500K) was measured. According to the transmittance of human eye at different ages (1-100 years old), the effective spectral distribution of the LED backlight displayer on the retina of the human eye at different ages was calculated. Based on the fitting of the response function of the human eye, the correlation studies on the changes of the blue light hazard factor, the proportion of blue light in the range of wavelength 400-500 nm, the circadian rhythm factor, and the proportion of blue light in the range of wavelength 446-477 nm with color temperature and age were conducted respectively. The results showed that the blue light hazard and circadian rhythm increased with the increase of the color temperature while decreased with the increase of age. For one-year-old infants, when the color temperature increased from 1200K to 6500K, the blue light hazard factor and circadian rhythm factor of the effective spectrum of the retina increased by 12.2 and 9.5 times respectively. For a 6500K LED backlight displayer, when the age increased from 1-year-old to 100 years old, the corresponding value of the two factors decreased by 0.2 and 0.3 times respectively. The proportion of blue light in the range of wavelength 400-500 nm can be used to approximately replace the blue light hazard factor to demonstrate the degree of blue light hazard. This conclusion can provide a certain theoretical reference for the personalized design and use of LED backlight displayer from the perspective of blue light hazard and circadian rhythm.

Influence of dietary Salicornia europaea L. extract supplementation on feed efficiency of Altay sheep by modifying their gastrointestinal bacteria communities.

This experiment aimed to examine the impact of Salicornia europaea L. extract on sheep growth performance, rumen fermentation variables, nutrient apparent digestibility, and gastrointestinal microbial diversity. Forty-eight male Altay sheep, weighing 32.5 ± 2.8 kg and approximately 3.5 months old, were chosen. Four dietary treatments, each consisting of four replicates and three sheep per replicate, were distributed randomly to the sheep. The pelleted total mixed ration containing Salicornia europaea L. extract at 0.0, 0.2, 0.4, and 0.6% DM was freely available to the sheep in the four treatment groups. The 56-day experiment consisted of 45 days of measurements followed by 11 days of adaptation. The growth performance was not affected by nutrition Salicornia europaea L. extract (p ≤ 0.05), but the feed-to-gain ratio was reduced when the extract was given at 0.4% DM (p ≤ 0.05). Compared to the 0 and 0.2% treatments, the apparent digestibility of DM, OM, NDF, and ADF was substantially greater in the 0.4, and 0.6% treatments. Furthermore, compared to sheep in the 0 and 0.2% groups, sheep in the 0.6% group had a noticeably higher apparent digestibility of CP. As the amount of Salicornia europaea L. extract added to the rumen fluid rose, the molar ratio of acetic acid increased. In contrast, the molar ratio of propionic acid gradually decreased, and the total volatile fatty acid content gradually reduced. Thus, adding a suitable quantity of Salicornia europaea L. extract to the sheep ration is natural and secure, which may improve the environmental sustainability of small ruminant production systems.

The polymorphisms on Igkappa gene are related to susceptibility of breast cancer and gastric cancer.

The phenomenon of immunoglobulin (Ig) expression in cancer cells has been discovered recently; the Ig protein expressed and secreted in cancer cells was found to be in favor of tumor growth. Two single-nucleotide polymorphism (SNP) loci rs232230 (5658C/G) and rs232228 (3635T/C) were identified on Igkappa gene previously, and we have demonstrated that they were associated with nasopharyngeal carcinoma susceptibility. In the present study, we further performed the study focused on these two SNPs in gastric and breast cancer, trying to demonstrate the association between the genotypes of the two SNPs and the susceptibility of gastric cancer and breast cancer. Our results suggested that the 5658-G allele and 3635-C allele were risk factors for both gastric cancer (odds ratio [OR]: 1.64 and 1.67, respectively) and breast cancer (OR: 1.94 and 1.56, respectively). Further, we also identified that they were related to other risk factors, including Helicobacter pylori (Hp) infection in gastric cancer and age in breast cancer.