Detalhe da pesquisa
1.
APOE3ch alters microglial response and suppresses Aß-induced tau seeding and spread.
Cell
; 187(2): 428-445.e20, 2024 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086389
2.
TREM2 drives microglia response to amyloid-ß via SYK-dependent and -independent pathways.
Cell
; 185(22): 4153-4169.e19, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36306735
3.
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Immunity
; 56(5): 1027-1045.e8, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36791722
4.
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Nature
; 615(7953): 668-677, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890231
5.
Transcriptomic mapping uncovers Purkinje neuron plasticity driving learning.
Nature
; 605(7911): 722-727, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545673
6.
Sex-dependent effects of acute stress on amyloid-ß in male and female mice.
Brain
; 146(6): 2268-2274, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37127299
7.
Aqp4 stop codon readthrough facilitates amyloid-ß clearance from the brain.
Brain
; 145(9): 2982-2990, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36001414
8.
Targeting primary and metastatic uveal melanoma with a G protein inhibitor.
J Biol Chem
; 296: 100403, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577798
9.
Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aß production and related pathology in a mouse model of Alzheimer's disease.
J Neurochem
; 156(5): 658-673, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33278025
10.
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification.
Alzheimers Dement
; 17(8): 1365-1382, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33559354
11.
Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopment.
Neurobiol Learn Mem
; 165: 106834, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29550366
12.
A spectrum of exercise training reduces soluble Aß in a dose-dependent manner in a mouse model of Alzheimer's disease.
Neurobiol Dis
; 85: 218-224, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26563933
13.
TREM2 regulates microglial cell activation in response to demyelination in vivo.
Acta Neuropathol
; 129(3): 429-47, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631124
14.
A role for δ subunit-containing GABA A receptors on parvalbumin positive neurons in maintaining electrocortical signatures of sleep states.
bioRxiv
; 2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585911
15.
Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB.
J Neurodev Disord
; 16(1): 16, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38632525
16.
Functional network disorganization and cognitive decline following fractionated whole-brain radiation in mice.
Geroscience
; 46(1): 543-562, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37749370
17.
The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.
bioRxiv
; 2024 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961719
18.
Effects of Complete and Partial Loss of the 24S-Hydroxycholesterol-Generating Enzyme Cyp46a1 on Behavior and Hippocampal Transcription in Mouse.
Biomolecules
; 14(3)2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38540675
19.
Kir6.2-K ATP channels alter glycolytic flux to modulate cortical activity, arousal, and sleep-wake homeostasis.
bioRxiv
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464274
20.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Neuron
; 112(3): 384-403.e8, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995685