Detalhe da pesquisa
1.
1,2,3-Triazolo[4,5-b]aminoquinolines: Design, synthesis, structure, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity, and molecular docking of novel modified tacrines.
Bioorg Chem
; 139: 106704, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37453239
2.
Bromo-Substituted Diazenyl-pyrazolo[1,5-a]pyrimidin-2-amines: Sonogashira Cross-Coupling Reaction, Photophysical Properties, Bio-interaction and HSA Light-Up Sensor.
Chembiochem
; 23(14): e202200248, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570195
3.
Hybridized 4-Trifluoromethyl-(1,2,3-triazol-1-yl)quinoline System: Synthesis, Photophysics, Selective DNA/HSA Bio-interactions and Molecular Docking.
Chembiochem
; 23(4): e202100649, 2022 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34878702
4.
Substituent-Driven Selective N-/O-Alkylation of 4-(Trihalomethyl)pyrimidin-2(1H)-ones Using Brominated Enones.
J Org Chem
; 87(7): 4590-4602, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285227
5.
2,2,2-trifluoro-1-(1,4,5,6-tetrahydropyridin-3-yl)ethanone derivative as efflux pump inhibitor in Mycobacterium tuberculosis.
Bioorg Med Chem Lett
; 42: 128088, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964440
6.
7-Amine-spiro[chromeno[4,3-b]quinoline-6,1'-cycloalkanes]: Synthesis and cholinesterase inhibitory activity of structurally modified tacrines.
Bioorg Chem
; 108: 104649, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33517001
7.
Photophysical, photostability, and ROS generation properties of new trifluoromethylated quinoline-phenol Schiff bases.
Beilstein J Org Chem
; 17: 2799-2811, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34925619
8.
Synthesis of N-Pyrrolyl(furanyl)-Substituted Piperazines, 1,4-Dizepanes, and 1,4-Diazocanes.
J Org Chem
; 84(14): 8976-8983, 2019 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31259554
9.
Chemo- and regioselective reactions of 5-bromo enones/enaminones with pyrazoles.
Org Biomol Chem
; 17(9): 2384-2392, 2019 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30724957
10.
Tacrine derivatives stimulate human glioma SF295 cell death and alter important proteins related to disease development: An old drug for new targets.
Biochim Biophys Acta Gen Subj
; 1862(7): 1527-1536, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29704527
11.
Effect of slight structural changes on the gelation properties of N-phenylstearamide supramolecular gels.
Soft Matter
; 14(32): 6716-6727, 2018 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30062361
12.
Synthesis of novel trifluoromethyl-substituted spiro-[chromeno[4,3-d]pyrimidine-5,1'-cycloalkanes], and evaluation of their analgesic effects in a mouse pain model.
Bioorg Med Chem Lett
; 27(7): 1551-1556, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28259627
13.
Synthesis, Crystal Structure, and Supramolecular Understanding of 1,3,5-Tris(1-phenyl-1H-pyrazol-5-yl)benzenes.
Molecules
; 23(1)2017 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29271950
14.
Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines.
Beilstein J Org Chem
; 13: 2396-2407, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29181120
15.
Regiochemistry of cyclocondensation reactions in the synthesis of polyazaheterocycles.
Beilstein J Org Chem
; 13: 257-266, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28326135
16.
Regioselectively Controlled Synthesis of N-Substituted (Trifluoromethyl)pyrimidin-2(1H)-ones.
J Org Chem
; 81(9): 3727-34, 2016 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27070191
17.
Synthesis and antinociceptive activity of new 2-substituted 4-(trifluoromethyl)-5,6-dihydrobenzo[h]quinazolines.
Bioorg Med Chem Lett
; 26(19): 4808-4814, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27561714
18.
Chemoselective Synthesis of 1-Substituted 4-Amino-2-(trifluoromethyl)-1H-pyrroles through the Heterocyclization Reaction of 4-Methoxy-5-bromo-1,1,1-trifluoropent-3-en-2-ones with Amines.
J Org Chem
; 80(24): 12453-9, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26583706
19.
Antitumoral activity of a trichloromethyl pyrimidine analogue: molecular cross-talk between intrinsic and extrinsic apoptosis.
Chem Res Toxicol
; 27(6): 1040-9, 2014 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848672
20.
Regiocontrolled Synthesis of 1-Substituted-3(5)-carboxyalkyl-1H-pyrazoles Using Trichloromethyl Enones.
ACS Omega
; 8(19): 17274-17287, 2023 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214703