Detalhe da pesquisa
1.
High-Throughput, Fluorescence-Based Esterase Activity Assay for Assessing Polysorbate Degradation Risk during Biopharmaceutical Development.
Pharm Res
; 38(3): 397-413, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33655394
2.
Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody.
MAbs
; 16(1): 2304282, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38269489
3.
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
MAbs
; 16(1): 2309685, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38356181
4.
High concentration formulation developability approaches and considerations.
MAbs
; 15(1): 2211185, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191233
5.
Gene editing of human embryonic stem cells via an engineered baculoviral vector carrying zinc-finger nucleases.
Mol Ther
; 19(5): 942-50, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21326219
6.
Deciphering deamidation and isomerization in therapeutic proteins: Effect of neighboring residue.
MAbs
; 14(1): 2143006, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36377085
7.
Targeting lentiviral vector to specific cell types through surface displayed single chain antibody and fusogenic molecule.
Virol J
; 7: 35, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20149250
8.
Impact of polymer geometry on the interactions of protein-PEG conjugates.
Biophys Chem
; 236: 22-30, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29331201
9.
Effect of Hierarchical Cluster Formation on the Viscosity of Concentrated Monoclonal Antibody Formulations Studied by Neutron Scattering.
J Phys Chem B
; 120(2): 278-91, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26707135
10.
High shear rheology and anisotropy in concentrated solutions of monoclonal antibodies.
J Pharm Sci
; 102(8): 2538-49, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873347