Clinical analysis of eight cases of fetal intracranial hemorrhage in pregnancy.

OBJECTIVE: To explore the clinical characteristics, treatment and prognosis of fetal intracranial hemorrhage in pregnancy and to improve the level of diagnosis and treatment. METHODS: We retrospectively analyzed the clinical data of eight cases of fetal intracranial hemorrhage in our hospital from 2014 to 2017, including the clinical manifestations, etiology, imaging features, treatment and prognosis. RESULTS: All the cases were diagnosed by prenatal color ultrasound or magnetic resonance imaging (MRI); one of the cases had decreased fetal movements and abnormal fetal heart rate monitoring, and the remaining seven cases had no special clinical symptoms. No clear cause was found in all the cases. Two patients with grade I fetal intracranial hemorrhage and 1 patient with grade II had a cesarean delivery, and no neurological sequelae were found in these neonates after 6 months of follow-up. There was one patient with grade III and four patients with grade IV fetal intracranial hemorrhage; one of the patients with grade IV was stillborn at the time of the discovery, and cesarean section was selected due to scarring of the uterus; intra-amniotic injection of ethacridine lactate was selected to induce labor in three cases, and vaginal delivery was selected; one of the patients with grade IV chose vaginal delivery, and the neonatal cranial brain magnetic resonance imaging after delivery showed no increase in intracranial lesions but showed incomplete development of the remaining nervous system. CONCLUSION: Fetal intracranial hemorrhage can be diagnosed by prenatal color ultrasound and MRI, yet it is often impossible to determine the cause. The prognosis of fetal intracranial hemorrhage is related to grade, and the prognosis of cerebral hemorrhage in patients with grades III-IV is poor.

[Spectra study of a sodion triethylenetetramine-bisdithiocarbamate and its complexes with heavy metal ions].

A sodion triethylenetetramine-bisdithiocarbamate (DTC-TETA) and its complexes with heavy metal ions were investigated by FTIR, UV, FAAS and elemental analysis, respectively. The FTIR spectrum of DTC-TETA showed strong absorption peaks at 1 461-1 388 cm(-1) and 1 174-996 cm(-1) which were attributed to partly double bonds of C-N and C-S, respectively. The UV spectrum of DTC-TETA had two absorption peaks at 265 and 290 nm, assigned to pi-pi* transition of N...C...S radical and nonbonding electron n-pi* transition of S...C...S radical to conjugated system, respectively. The elemental analysis results demonstrated that the mol ratio of C, H, N and S in DTC-TETA was about 2 : 4 : 1 : 1. As for UV spectrum of its complexes with Cu(II), Cd(II), Zn(II) and Ni(II), there were four new absorption peaks at 321, 310, 311 and 325 nm, respectively. Coupled to flow-injection, FAAS determination showed that the complexation performance of Cu2+, Cd2+, Ni2+ and Zn2+ complexes of DTC-TETA was better than that of sodium diethyldithiocarbamate (DDTC).