Detalhe da pesquisa
1.
Preclinical evidence using synthetic compounds and natural products indicates that AMPK represents a potential pharmacological target for the therapy of pulmonary diseases.
Med Res Rev
; 44(3): 1326-1369, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229486
2.
Artemisinin Confers Cytoprotection toward Hydrogen Peroxide-Induced Cell Apoptosis in Retinal Pigment Epithelial Cells in Correlation with the Increased Acetylation of Histone H4 at Lysine 8.
Molecules
; 29(8)2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675608
3.
Synthesis of a C2-Symmetric Chiral Borinic Acid and Its Application in Catalytic Desymmetrization of 2,2-Disubstituted-1,3-Propanediols.
J Am Chem Soc
; 2023 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37036443
4.
Dihydroartemisinin inhibits EMT of glioma via gene BASP1 in extrachromosomal DNA.
Biochem Biophys Res Commun
; 675: 130-138, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37473527
5.
Induced CPL-Active Materials Based on Chiral Supramolecular Co-Assemblies.
Chemistry
; 29(22): e202204039, 2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36691189
6.
Causal effect of gut-microbiota-derived metabolite trimethylamine N-oxide on Parkinson's disease: A Mendelian randomization study.
Eur J Neurol
; 30(11): 3451-3461, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36692876
7.
Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans.
BMC Biol
; 20(1): 71, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35317792
8.
Artemisia annua Extract Improves the Cognitive Deficits and Reverses the Pathological Changes of Alzheimer's Disease via Regulating YAP Signaling.
Int J Mol Sci
; 24(6)2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982332
9.
Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway.
Molecules
; 28(14)2023 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513399
10.
Planar Chiral Multiple Resonance Thermally Activated Delayed Fluorescence Materials for Efficient Circularly Polarized Electroluminescence.
Angew Chem Int Ed Engl
; 62(6): e202217045, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517419
11.
Enantioselective Construction of Tertiary α-Alkyl Fluoride via BTM-Catalyzed Fluorination of α-Alkynyl-Substituted Acetic Acids.
J Org Chem
; 87(1): 713-720, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34927437
12.
Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling.
Int J Mol Sci
; 23(11)2022 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35683033
13.
Quetiapine Shortens the Lifespan of Caenorhabditis elegans through DOP-2, DAF-2 and RSKS-1.
Int J Mol Sci
; 23(21)2022 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361717
14.
Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells.
Int J Mol Sci
; 23(22)2022 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430902
15.
The role of FOXOs and autophagy in cancer and metastasis-Implications in therapeutic development.
Med Res Rev
; 40(6): 2089-2113, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32474970
16.
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway.
J Cell Mol Med
; 24(11): 6208-6219, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32347651
17.
Computational Design of Enhanced Enantioselectivity in Chiral Phosphoric Acid-Catalyzed Oxidative Desymmetrization of 1,3-Diol Acetals.
J Am Chem Soc
; 142(18): 8506-8513, 2020 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283928
18.
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6.
Brain Behav Immun
; 88: 640-653, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32353516
19.
Artemisinin protects motoneurons against axotomy-induced apoptosis through activation of the PKA-Akt signaling pathway and promotes neural stem/progenitor cells differentiation into NeuN+ neurons.
Pharmacol Res
; 159: 105049, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32598944
20.
Metformin protects PC12 cells and hippocampal neurons from H2 O 2 -induced oxidative damage through activation of AMPK pathway.
J Cell Physiol
; 234(9): 16619-16629, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784077