[Function and regulation of long non-coding RNAs in tumorigenesis and host innate immunity-A review].

Long non-coding RNA(lncRNA) is a class of RNA transcripts with length over 200 nucleotides and absence of the ability to encode a functional protein. Although long non-coding RNAs were previously thought as transcriptional noises, increasing evidences have recently shown that they play important roles in a variety of cellular processes through regulating epigenetic modifications and thereby affecting gene transcription, post-transcriptional processing, and protein translation. Importantly, it has been found that abnormal expression or dysregulation of lncRNAs are closely associated with tumorigenesis and host innate immune response to various infections with pathogens. In this review, we will discuss the progresses in understanding the function of lncRNAs in these processes.

One-dimensional zinc-manganate oxide hollow nanostructures with enhanced supercapacitor performance.

Hollow electrode materials with structural advantages of large contact interface and sufficient cavity structures are significant for electrochemical energy storage. Herein, ultra-long one-dimensional zinc-manganese oxide (ZnMn2O4) hollow nanofibers were successfully prepared by electrospinning at an appropriate temperature (500 °C). The optimal electrode of ZnMn2O4 exhibited a larger specific capacitance (1026 F g-1) as compared to ZnMn2O4 powder (125 F g-1) at a current density of 2 A g-1 in three-electrode configuration. Moreover, the optimal electrode of the ZnMn2O4 hollow nanofibers also possessed long-term cycling stability with a slight upward capacitance (100.8%) after 5000 cycles. Their higher specific capacitance and the outstanding cycle stability may be attributed to the unique 1D hollow nanostructure, which enhanced the charge transfer and improved the diffusion of the electrolyte ions at the surface. Thus, this work designed a high-performance electrode with unique hollow nanostructure that can be applied to the field of energy storage.