Detalhe da pesquisa
1.
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell
; 183(4): 1058-1069.e19, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058755
2.
A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell
; 177(5): 1136-1152.e18, 2019 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31100268
3.
Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity
; 56(8): 1927-1938.e8, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506693
4.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity
; 56(3): 669-686.e7, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36889306
5.
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity.
Immunity
; 53(6): 1272-1280.e5, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242394
6.
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry.
Proc Natl Acad Sci U S A
; 121(22): e2310677121, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753503
7.
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc Natl Acad Sci U S A
; 120(24): e2216612120, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37276407
8.
Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc Natl Acad Sci U S A
; 119(21): e2200821119, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594401
9.
A broad and potent neutralization epitope in SARS-related coronaviruses.
Proc Natl Acad Sci U S A
; 119(29): e2205784119, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35767670
10.
N-Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses.
J Virol
; 96(5): e0212021, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35044215
11.
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc Natl Acad Sci U S A
; 117(31): 18431-18438, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690700
12.
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
PLoS Pathog
; 16(12): e1009089, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33275640
13.
F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice.
Hepatology
; 70(6): 1942-1957, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30703849
14.
Tumor Progression Locus 2 in Hepatocytes Potentiates Both Liver and Systemic Metabolic Disorders in Mice.
Hepatology
; 69(2): 524-544, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381809
15.
Integrated Omics Reveals Tollip as an Regulator and Therapeutic Target for Hepatic Ischemia-Reperfusion Injury in Mice.
Hepatology
; 70(5): 1750-1769, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31077413
16.
Targeting Transmembrane BAX Inhibitor Motif Containing 1 Alleviates Pathological Cardiac Hypertrophy.
Circulation
; 137(14): 1486-1504, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229612
17.
Three mutations switch H7N9 influenza to human-type receptor specificity.
PLoS Pathog
; 13(6): e1006390, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28617868
18.
Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver.
Hepatology
; 67(4): 1320-1338, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29077210
19.
Ubiquitin-Specific Peptidase 10 (USP10) Inhibits Hepatic Steatosis, Insulin Resistance, and Inflammation Through Sirt6.
Hepatology
; 68(5): 1786-1803, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698567
20.
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.
Nat Chem Biol
; 13(8): 845-849, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28604693