Detalhe da pesquisa
1.
SKLB-14b, a novel oral microtubule-destabilizing agent based on hydroxamic acid with potent anti-tumor and anti-multidrug resistance activities.
Bioorg Chem
; 128: 106053, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35964504
2.
Identification of the target protein and molecular mechanism of honokiol in anti-inflammatory action.
Phytomedicine
; 109: 154617, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36610140
3.
HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cells.
Bioact Mater
; 21: 483-498, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36185739
4.
Corrigendum: Honokiol ameliorates post-myocardial infarction heart failure through Ucp3-mediated reactive oxygen species inhibition.
Front Pharmacol
; 13: 1000887, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36238543
5.
Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.
Ann Med
; 54(1): 743-753, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35243950
6.
Honokiol Ameliorates Post-Myocardial Infarction Heart Failure Through Ucp3-Mediated Reactive Oxygen Species Inhibition.
Front Pharmacol
; 13: 811682, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35264952
7.
Structure-Based Design and Synthesis of N-Substituted 3-Amino-ß-Carboline Derivatives as Potent αß-Tubulin Degradation Agents.
J Med Chem
; 65(3): 2675-2693, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084853
8.
Identification of a Novel 2,8-Diazaspiro[4.5]decan-1-one Derivative as a Potent and Selective Dual TYK2/JAK1 Inhibitor for the Treatment of Inflammatory Bowel Disease.
J Med Chem
; 65(4): 3151-3172, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35113547
9.
A size-shrinkable matrix metallopeptidase-2-sensitive delivery nanosystem improves the penetration of human programmed death-ligand 1 siRNA into lung-tumor spheroids.
Drug Deliv
; 28(1): 1055-1066, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34078185
10.
Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity.
J Med Chem
; 64(20): 15379-15401, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34648295
11.
Antitumor Effects of Docetaxel in Truncated Basic Fibroblast Growth Factor- Functionalized Liposomes Delivered by d-α-tocopheryl Polyethylene Glycol 2000 Succinate.
Curr Pharm Des
; 26(34): 4338-4348, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32324508
12.
Anti-Tumor Study of H6, a 4-Substituted Coumarins Derivative, Loaded Biodegradable Self-Assembly Nano-Micelles In Vitro and In Vivo.
J Biomed Nanotechnol
; 15(7): 1515-1531, 2019 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31196355
13.
Purinostat Mesylate Is a Uniquely Potent and Selective Inhibitor of HDACs for the Treatment of BCR-ABL-Induced B-Cell Acute Lymphoblastic Leukemia.
Clin Cancer Res
; 25(24): 7527-7539, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439580
14.
Correction to "Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity".
J Med Chem
; 65(17): 11890, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998325