Detalhe da pesquisa
1.
Female C57BL/6N mice are a viable model of aortic aging in women.
Am J Physiol Heart Circ Physiol
; 324(6): H893-H904, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37115626
2.
Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice.
J Physiol
; 599(3): 911-925, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33103241
3.
Suppression of the gut microbiome ameliorates age-related arterial dysfunction and oxidative stress in mice.
J Physiol
; 597(9): 2361-2378, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30714619
4.
Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice.
J Physiol
; 592(12): 2549-61, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24665093
5.
The plasma metabolome is associated with preservation of physiological function following lifelong aerobic exercise in mice.
Geroscience
; 46(3): 3311-3324, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265578
6.
Lifelong physical activity attenuates age- and Western-style diet-related declines in physical function and adverse changes in skeletal muscle mass and inflammation.
Exp Gerontol
; 157: 111632, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822971
7.
Late-life voluntary wheel running reverses age-related aortic stiffness in mice: a translational model for studying mechanisms of exercise-mediated arterial de-stiffening.
Geroscience
; 43(1): 423-432, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32529594
8.
Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans.
Hypertension
; 78(2): 499-511, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33966451
9.
Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans.
Hypertension
; 76(1): 101-112, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32520619
10.
Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Aging Cell
; 19(1): e13074, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31755162
11.
Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways.
Aging Cell
; 16(1): 17-26, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27660040
12.
Voluntary aerobic exercise increases arterial resilience and mitochondrial health with aging in mice.
Aging (Albany NY)
; 8(11): 2897-2914, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875805
13.
Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism.
Mech Ageing Dev
; 133(5): 368-71, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22484146