Seroprevalence of COVID-19 in Oran: Cross-Sectional Study.

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was introduced in Algeria in March 2020. This study aimed to estimate the seroprevalence of SARS-CoV-2 infection in Oran, Algeria, and to identify factors associated with seropositivity. This was a cross-sectional seroprevalence study conducted between 7 and 20 January 2021 across all 26 municipalities in the province of Oran. The study employed a random cluster sampling technique stratified by age and sex to select participants from households, who were then administered a rapid serological test. The overall seroprevalence and specific seroprevalences by municipality were calculated, and the number of COVID-19 cases in Oran was estimated. The correlation between population density and seroprevalence was also examined. Among the participants, 422 (35.6%; 95% confidence interval [CI], 32.9 to 38.4) had a positive serological test for SARS-CoV-2, and eight municipalities had seroprevalence rates above 73%. We found a strong positive correlation between population density and seroprevalence (r = 0.795, P < 0.001), indicating that areas with higher population density had higher numbers of positive COVID-19 cases. Our study provides evidence of a high seroprevalence of SARS-CoV-2 infection in Oran, Algeria. The estimated number of cases based on seroprevalence is much higher than the number of cases confirmed by PCR. Our findings suggest that a large proportion of the population has been infected with SARS-CoV-2, highlighting the need for continued surveillance and control measures to prevent further spread of the virus. IMPORTANCE This is the first and only seroprevalence study of COVID-19 conducted in the general population in Algeria prior to the national vaccination campaign against COVID-19. The significance of this study lies in its contribution to our understanding of the spread of the virus in the population before the implementation of the vaccination program.

Accidents exposing blood to the staff of a hospital and university establishment in Algeria: Assessment and risk factors.

Background: Accidents exposing to blood AEB represent real public health problem in healthcare establishments. The objective of our study was to estimate the frequency of AEB As at our establishment as well as the risk factors that determine their occurrence. Patients and Methods: A cross-sectional descriptive survey was conducted at a hospital university establishment over period from October 16 to December 3, 2018. The survey concerned accident exposing blood to the staff of our establishment. Data entry and analysis was carried out using Epi-Info software. Results: A clear predominance of women was noted (79.2%) among the study population with a Sex ratio equal to 0.26. The average age was 27.7 ± 6.2 years.The frequency of exposure to AEB among hospital staff was 48.5%. Needlestick injuries were the most common accident (88.3%), followed by splashing blood or body fluids (51.7%), and cutting with a sharp object (10.0%).Among the risk factors significantly associated with the occurrence of AEB, we can cite the medical profession (OR = 3.94; p <0.001), the surgical specialty (OR = 3.3; p <0.01), the male sex (OR = 3.7; p <0.01). Likewise, risk of AEB increased significantly with age (p <0.01) and professional seniority (p <0.02).