Detalhe da pesquisa
1.
Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
J Biol Chem
; 291(10): 5185-98, 2016 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26702054
2.
Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial.
Lancet
; 387(10024): 1178-86, 2016 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26803443
3.
Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality.
Circ Res
; 114(1): 101-8, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24065463
4.
Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.
Circulation
; 128(5): 512-23, 2013 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804254
5.
Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells.
Circ Res
; 111(11): 1434-45, 2012 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22931954
6.
Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts.
Mol Ther
; 20(3): 565-71, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22215018
7.
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure.
Circulation
; 124(3): 304-13, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21709064
8.
Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model.
J Vis Exp
; (189)2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36440832
9.
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.
J Card Fail
; 15(3): 171-81, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19327618
10.
Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.
J Card Fail
; 14(5): 355-67, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18514926
11.
Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension: A Large Animal Model.
J Am Coll Cardiol
; 67(17): 2032-46, 2016 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27126531
12.
Stem cell factor gene transfer improves cardiac function after myocardial infarction in swine.
Circ Heart Fail
; 8(1): 167-74, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342737
13.
Effect of Recombinant Human c-kit Receptor Ligand on Mediator Release from Human Skin Mast Cells.
Int Arch Allergy Immunol
; 99(2-4): 323-325, 1992.
Artigo
em Inglês
| MEDLINE | ID: mdl-34167212
14.
Design of a phase 2b trial of intracoronary administration of AAV1/SERCA2a in patients with advanced heart failure: the CUPID 2 trial (calcium up-regulation by percutaneous administration of gene therapy in cardiac disease phase 2b).
JACC Heart Fail
; 2(1): 84-92, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24622121
15.
Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.
J Biomol Screen
; 19(2): 215-22, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24436077
16.
High-throughput FRET assay yields allosteric SERCA activators.
J Biomol Screen
; 18(1): 97-107, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22923787
17.
Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure.
J Am Coll Cardiol
; 51(11): 1112-9, 2008 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18342232
18.
Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins.
J Mol Cell Cardiol
; 42(4): 852-61, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17300800
19.
Measurement of human and murine stem cell factor (c-kit ligand).
Curr Protoc Immunol
; Chapter 6: 6.17.1-6.17.11, 2001 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18432808