Detalhe da pesquisa
1.
Structure-activity relationship of dihydropyridines for rhabdomyosarcoma.
Biochem Biophys Res Commun
; 667: 138-145, 2023 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224633
2.
NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.
Breast Cancer Res Treat
; 189(1): 49-61, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34196902
3.
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
Int J Mol Sci
; 22(2)2021 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33429995
4.
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Anticancer Drugs
; 31(8): 759-775, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32796402
5.
Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines.
Bioorg Med Chem Lett
; 30(16): 127284, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631507
6.
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).
Molecules
; 25(7)2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32272798
7.
In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds.
Molecules
; 25(2)2020 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31941153
8.
Quinazoline-Based Antivirulence Compounds Selectively Target Salmonella PhoP/PhoQ Signal Transduction System.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611347
9.
Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK).
Bioorg Med Chem Lett
; 29(14): 1727-1731, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31129055
10.
Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines.
Bioorg Med Chem Lett
; 29(18): 2695-2699, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31378571
11.
New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors.
Biochem J
; 475(15): 2435-2455, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934490
12.
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors.
Biochem J
; 475(15): 2417-2433, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934491
13.
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Molecules
; 24(22)2019 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31698822
14.
A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA.
J Biol Chem
; 292(41): 17037-17045, 2017 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821610
15.
1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.
Molecules
; 23(5)2018 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783765
16.
Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling.
J Biol Chem
; 291(18): 9566-80, 2016 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26933036
17.
High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-translational modification.
J Gen Virol
; 98(4): 754-768, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100301
18.
EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen.
J Pathol
; 239(3): 320-34, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102572
19.
Transactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating Element.
J Biol Chem
; 290(28): 17611-27, 2015 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26028650
20.
Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.
J Immunol
; 192(4): 1796-805, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24431232