Pesquisa | BVS IEC

1.

Silencing of Dok-7 in Adult Rat Muscle Increases Susceptibility to Passive Transfer Myasthenia Gravis.

Gomez, Alejandro M; Stevens, Jo A A; Mané-Damas, Marina; Molenaar, Peter; Duimel, Hans; Verheyen, Fons; Cossins, Judith; Beeson, David; De Baets, Marc H; Losen, Mario; Martinez-Martinez, Pilar.

Am J Pathol ; 186(10): 2559-68, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27658713

2.

IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients.

Koneczny, Inga; Stevens, Jo A A; De Rosa, Anna; Huda, Saif; Huijbers, Maartje G; Saxena, Abhishek; Maestri, Michelangelo; Lazaridis, Konstantinos; Zisimopoulou, Paraskevi; Tzartos, Socrates; Verschuuren, Jan; van der Maarel, Silvère M; van Damme, Philip; De Baets, Marc H; Molenaar, Peter C; Vincent, Angela; Ricciardi, Roberta; Martinez-Martinez, Pilar; Losen, Mario.

J Autoimmun ; 77: 104-115, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-27965060

3.

Complement activation by ceramide transporter proteins.

Bode, Gerard H; Losen, Mario; Buurman, Wim A; Veerhuis, Robert; Molenaar, Peter C; Steinbusch, Harry W M; De Baets, Marc H; Daha, Mohamed R; Martinez-Martinez, Pilar.

J Immunol ; 192(3): 1154-61, 2014 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-24395916

4.

Proteasome inhibition with bortezomib depletes plasma cells and specific autoantibody production in primary thymic cell cultures from early-onset myasthenia gravis patients.

Gomez, Alejandro M; Willcox, Nick; Vrolix, Kathleen; Hummel, Jonas; Nogales-Gadea, Gisela; Saxena, Abhishek; Duimel, Hans; Verheyen, Fons; Molenaar, Peter C; Buurman, Wim A; De Baets, Marc H; Martinez-Martinez, Pilar; Losen, Mario.

J Immunol ; 193(3): 1055-1063, 2014 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-24973445

5.

Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor.

Vrolix, Kathleen; Fraussen, Judith; Losen, Mario; Stevens, Jo; Lazaridis, Konstantinos; Molenaar, Peter C; Somers, Veerle; Bracho, Maria Alma; Le Panse, Rozen; Stinissen, Piet; Berrih-Aknin, Sonia; Maessen, Jos G; Van Garsse, Leen; Buurman, Wim A; Tzartos, Socrates J; De Baets, Marc H; Martinez-Martinez, Pilar.

J Autoimmun ; 52: 101-12, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24439114

6.

Implication of double-stranded RNA signaling in the etiology of autoimmune myasthenia gravis.

Cufi, Perrine; Dragin, Nadine; Weiss, Julia Miriam; Martinez-Martinez, Pilar; De Baets, Marc H; Roussin, Régine; Fadel, Elie; Berrih-Aknin, Sonia; Le Panse, Rozen.

Ann Neurol ; 73(2): 281-93, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23280437

7.

Fetal asphyxia induces acute and persisting changes in the ceramide metabolism in rat brain.

Vlassaks, Evi; Mencarelli, Chiara; Nikiforou, Maria; Strackx, Eveline; Ferraz, Maria J; Aerts, Johannes M; De Baets, Marc H; Martinez-Martinez, Pilar; Gavilanes, Antonio W D.

J Lipid Res ; 54(7): 1825-33, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23625371

8.

Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques.

Mencarelli, Chiara; Bode, Gerard H; Losen, Mario; Kulharia, Mahesh; Molenaar, Peter C; Veerhuis, Robert; Steinbusch, Harry W M; De Baets, Marc H; Nicolaes, Gerry A F; Martinez-Martinez, Pilar.

J Biol Chem ; 287(18): 14897-911, 2012 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-22396542

9.

Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis.

Gomez, Alejandro M; Vrolix, Kathleen; Martínez-Martínez, Pilar; Molenaar, Peter C; Phernambucq, Marko; van der Esch, Eline; Duimel, Hans; Verheyen, Fons; Voll, Reinhard E; Manz, Rudolf A; De Baets, Marc H; Losen, Mario.

J Immunol ; 186(4): 2503-13, 2011 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-21239719

10.

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice.

Klooster, Rinse; Plomp, Jaap J; Huijbers, Maartje G; Niks, Erik H; Straasheijm, Kirsten R; Detmers, Frank J; Hermans, Pim W; Sleijpen, Kevin; Verrips, Aad; Losen, Mario; Martinez-Martinez, Pilar; De Baets, Marc H; van der Maarel, Silvère M; Verschuuren, Jan J.

Brain ; 135(Pt 4): 1081-101, 2012 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-22396395

11.

Outcomes after robotic thymectomy in nonthymomatous versus thymomatous patients with acetylcholine-receptor-antibody-associated myasthenia gravis.

Marcuse, Florit; Hoeijmakers, Janneke G J; Hochstenbag, Monique; Hamid, Myrurgia Abdul; Keijzers, Marlies; Mané-Damas, Marina; Martinez-Martinez, Pilar; Verschuuren, Jan; Kuks, Jan; Beekman, Roy; van der Kooi, Anneke J; van Doorn, Pieter; van Es, Michael; Maessen, Jos J G; De Baets, Marc H V.

Neuromuscul Disord ; 33(5): 417-424, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37037051

12.

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.

Bosma, Madeleen; Minnaard, Ronnie; Sparks, Lauren M; Schaart, Gert; Losen, Mario; de Baets, Marc H; Duimel, Hans; Kersten, Sander; Bickel, Perry E; Schrauwen, Patrick; Hesselink, Matthijs K C.

Histochem Cell Biol ; 137(2): 205-16, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22127648

13.

Novel treatment strategies for acetylcholine receptor antibody-positive myasthenia gravis and related disorders.

Mané-Damas, Marina; Molenaar, Peter C; Ulrichts, Peter; Marcuse, Florit; De Baets, Marc H; Martinez-Martinez, Pilar; Losen, Mario.

Autoimmun Rev ; 21(7): 103104, 2022 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-35452851

14.

Robotic Thymectomy for Thymomas: A Retrospective Follow-up Study in the Netherlands.

Marcuse, Florit; Hochstenbag, Monique; De Baets, Marc H V; Bootsma, Gerben; Maat, Alexander P W M; Hoeijmakers, Janneke G J; Keijzers, Marlies; Abdul Hamid, Myrurgia; De Ruysscher, Dirk; Maessen, Jos G.

Ann Thorac Surg ; 114(5): 1886-1894, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-34736927

15.

Peripheral neuropathy in myotonic dystrophy type 1.

Hermans, Mieke C E; Faber, Catharina G; Vanhoutte, Els K; Bakkers, Mayienne; De Baets, Marc H; de Die-Smulders, Christine E M; Merkies, Ingemar S J.

J Peripher Nerv Syst ; 16(1): 24-9, 2011 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-21504499

16.

Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.

Luo, Jie; Taylor, Palmer; Losen, Mario; de Baets, Marc H; Shelton, G Diane; Lindstrom, Jon.

J Neurosci ; 29(44): 13898-908, 2009 Nov 04.

Artigo em Inglês | MEDLINE | ID: mdl-19890000

17.

The ceramide transporter and the Goodpasture antigen binding protein: one protein--one function?

Mencarelli, Chiara; Losen, Mario; Hammels, Caroline; De Vry, Jochen; Hesselink, Matthijs K C; Steinbusch, Harry W M; De Baets, Marc H; Martínez-Martínez, Pilar.

J Neurochem ; 113(6): 1369-86, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20236389

18.

IgG4-related disease.

Niks, Erik H; De Baets, Marc H; Verschuuren, Jan J G M.

N Engl J Med ; 366(17): 1644-5; author reply 1646-7, 2012 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-22533592

19.

The effect of plasma from muscle-specific tyrosine kinase myasthenia patients on regenerating endplates.

ter Beek, W Pascale; Martínez-Martínez, Pilar; Losen, Mario; de Baets, Marc H; Wintzen, Axel R; Verschuuren, Jan J G M; Niks, Erik H; van Duinen, Sjoerd G; Vincent, Angela; Molenaar, Peter C.

Am J Pathol ; 175(4): 1536-44, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-19745065

20.

Glycine receptor antibodies in PERM: a new channelopathy.

Martinez-Martinez, Pilar; Molenaar, Peter C; Losen, Mario; de Baets, Marc H.

Brain ; 137(Pt 8): 2115-6, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25057131

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Instituto Evandro Chagas

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