Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Mais filtros

Base de dados
País/Região como assunto
Tipo de documento
Intervalo de ano de publicação
1.
Clin Infect Dis ; 65(9): 1504-1508, 2017 Oct 16.
Artigo em Inglês | MEDLINE | ID: mdl-29048510

RESUMO

BACKGROUND: Invasive and disseminated Mycoplasma hominis infections are well recognized but uncommon complications in solid organ transplant recipients. In a single center, a cluster of M. hominis infections were identified in lung transplant recipients from the same thoracic intensive care unit (ICU). We sought to determine the source(s) of these infections. METHODS: Medical records of the donor and infected transplant recipients were reviewed for clinical characteristics. Clinical specimens underwent routine processing with subculture on Mycoplasma-specific Hayflick agar. Mycoplasma hominis identification was confirmed using sequencing of the 16S ribosomal RNA gene. Mycoplasma hominis isolates were subjected to whole-genome sequencing on the Illumina NextSeq platform. RESULTS: Three lung transplant recipients presented with invasive M. hominis infections at multiple sites characterized by purulent infections without organisms detected by Gram staining. Each patient had a separate donor; however, pretransplant bronchoalveolar lavage fluid was only available from the donor for patient 1, which subsequently grew M. hominis. Phylo- and pangenomic analyses indicated that the isolates from the donor and the corresponding recipient (patient 1) were closely related and formed a distinct single clade. In contrast, isolates from patients 2 and 3 were unrelated and divergent from one another. CONCLUSIONS: Mycoplasma hominis should be considered a cause of donor-derived infection. Genomic data suggest donor-to-recipient transmission of M. hominis. Additional patients co-located in the ICU were found to have genetically unrelated M. hominis isolates, excluding patient-to-patient transmission.


Assuntos
Transplante de Pulmão/efeitos adversos , Infecções por Mycoplasma/etiologia , Infecções por Mycoplasma/microbiologia , Mycoplasma hominis/genética , Transplantados , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Filogenia , Doadores de Tecidos
2.
J Med Microbiol ; 52(Pt 9): 839-842, 2003 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-12909664

RESUMO

Francisella tularensis is found throughout the Northern Hemisphere, where it is associated with the disease of tularaemia in animals and humans. The isolation and identification is reported of a novicida-like subspecies of F. tularensis from a foot wound sustained in brackish water in the Northern Territory of Australia.


Assuntos
Francisella tularensis/classificação , Francisella tularensis/isolamento & purificação , Dedos do Pé/microbiologia , Tularemia/microbiologia , Infecção dos Ferimentos/microbiologia , Adulto , Técnicas de Tipagem Bacteriana , DNA Ribossômico/análise , Francisella tularensis/genética , Humanos , Masculino , Dados de Sequência Molecular , Northern Territory , RNA Ribossômico 16S/genética , Análise de Sequência de DNA
4.
Med J Aust ; 192(6): 348-50, 2010 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-20230355

RESUMO

Haemophilus ducreyi is a well recognised causative agent of genital ulcers and chancroid. We report two unusual cases of non-sexually transmitted H. ducreyi infection leading to chronic lower limb ulcers. Both patients were Australian expatriates visiting Australia from the Pacific Islands--one from Papua New Guinea and the other from Vanuatu.


Assuntos
Cancroide/complicações , Haemophilus ducreyi/isolamento & purificação , Úlcera Cutânea/etiologia , Antibacterianos/uso terapêutico , Biópsia , Cancroide/diagnóstico , Cancroide/microbiologia , Doença Crônica , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Pele/microbiologia , Pele/patologia , Úlcera Cutânea/diagnóstico , Úlcera Cutânea/tratamento farmacológico
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA