Detalhe da pesquisa
1.
Administration of oxathridine, a first-in-class histamine-3 receptor partial agonist in healthy male volunteers: Central nervous system depression and pseudo-hallucinations.
Br J Clin Pharmacol
; 90(1): 321-335, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37724688
2.
Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers.
J Pharmacol Exp Ther
; 386(2): 129-137, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316329
3.
A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers.
Exp Dermatol
; 32(7): 1028-1041, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37051698
4.
A Biomarker Study in Patients with GBA1-Parkinson's Disease and Healthy Controls.
Mov Disord
; 38(5): 783-795, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36916660
5.
Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial.
Int J Mol Sci
; 24(18)2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37762625
6.
Clinical validation of digital biomarkers for paediatric patients with asthma and cystic fibrosis: potential for clinical trials and clinical care.
Eur Respir J
; 59(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887326
7.
Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers.
Br J Clin Pharmacol
; 88(6): 2909-2925, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014069
8.
Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer's disease.
Br J Clin Pharmacol
; 88(6): 2814-2829, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34964149
9.
Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.
Br J Clin Pharmacol
; 88(2): 680-690, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293819
10.
Topical antimicrobial peptide omiganan recovers cutaneous dysbiosis but does not improve clinical symptoms in patients with mild to moderate atopic dermatitis in a phase 2 randomized controlled trial.
J Am Acad Dermatol
; 86(4): 854-862, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33010325
11.
Proof of pharmacology of Org 48775-0, a p38 MAP kinase inhibitor, in healthy volunteers.
Br J Clin Pharmacol
; 87(5): 2321-2332, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33201520
12.
Safety, tolerability and pharmacokinetic characterisation of DACRA KBP-042 in healthy male subjects.
Br J Clin Pharmacol
; 87(12): 4786-4796, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019711
13.
A randomized single and multiple ascending dose study in healthy volunteers of LTI-291, a centrally penetrant glucocerebrosidase activator.
Br J Clin Pharmacol
; 87(9): 3561-3573, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576113
14.
Comprehensive evaluation of microneedle-based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial.
Br J Clin Pharmacol
; 87(8): 3162-3176, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33403697
15.
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a Highly Selective NaV1.8 Inhibitor, in Healthy Male Adults.
Pain Med
; 22(8): 1814-1826, 2021 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33543763
16.
Guselkumab induction therapy demonstrates long-lasting efficacy in patients with mild psoriasis, results from a randomized, placebo-controlled exploratory clinical trial.
J Am Acad Dermatol
; 90(2): 395-397, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37804933
17.
Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?
Int J Mol Sci
; 20(19)2019 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31547590
18.
Reversal of mecamylamine-induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses.
Br J Clin Pharmacol
; 84(5): 888-899, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29319910
19.
No effect of topical digoxin and furosemide for patients with actinic keratosis.
J Eur Acad Dermatol Venereol
; 37(2): e172-e174, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36177541
20.
Pharmacodynamic response profiles of anxiolytic and sedative drugs.
Br J Clin Pharmacol
; 83(5): 1028-1038, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27922194