Detalhe da pesquisa
1.
Anticancer Activity of Chalcones and Its Derivatives: Review and In Silico Studies.
Molecules
; 28(10)2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37241750
2.
In vitro anti-Leishmania activity and molecular docking of spiro-acridine compounds as potential multitarget agents against Leishmania infantum.
Bioorg Med Chem Lett
; 49: 128289, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34311084
3.
Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
Bioorg Med Chem
; 26(22): 5911-5921, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420325
4.
Effect of antiprotozoal molecules on hypnospores of Perkinsus spp. parasite.
Exp Parasitol
; 192: 25-35, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30028986
5.
Synthesis, DNA Binding, and Antiproliferative Activity of Novel Acridine-Thiosemicarbazone Derivatives.
Int J Mol Sci
; 16(6): 13023-42, 2015 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068233
6.
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety.
Int J Biol Macromol
; 254(Pt 3): 127651, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37949265
7.
Would the Development of a Multitarget Inhibitor of 3CLpro and TMPRSS2 be Promising in the Fight Against SARS-CoV-2?
Med Chem
; 19(5): 405-412, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36221875
8.
Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases.
Eur J Med Chem
; 258: 115550, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37336067
9.
Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies.
Sci Rep
; 13(1): 7320, 2023 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37147323
10.
Overview of the New Bioactive Heterocycles as Targeting Topoisomerase Inhibitors Useful Against Colon Cancer.
Anticancer Agents Med Chem
; 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38038012
11.
The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors.
Mini Rev Med Chem
; 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37680157
12.
Anti-Inflammatory Activity of N'-(3-(1H-indol-3-yl)benzylidene)-2-cyanoacetohydrazide Derivative via sGC-NO/Cytokine Pathway.
Pharmaceuticals (Basel)
; 16(10)2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37895886
13.
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation.
Pharmaceuticals (Basel)
; 16(2)2023 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37259353
14.
Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses.
Curr Top Med Chem
; 22(29): 2435-2462, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36415099
15.
Topoisomerase Enzyme Inhibitors as Potential Drugs Against Cancer: What Makes Them Selective or Dual? - A Review.
Curr Pharm Des
; 28(34): 2800-2824, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35909281
16.
Application of Heterocycles as an Alternative for the Discovery of New Anti-ulcer Compounds: A Mini-Review.
Curr Pharm Des
; 28(17): 1373-1388, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35549862
17.
The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases.
Pharmaceutics
; 14(1)2022 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35057082
18.
Apoptotic and antioxidant effects in HCT-116 colorectal carcinoma cells by a spiro-acridine compound, AMTAC-06.
Pharmacol Rep
; 74(3): 545-554, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35297003
19.
Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders.
Int J Biol Macromol
; 170: 622-635, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359805
20.
Thiophene-Based Compounds with Potential Anti-Inflammatory Activity.
Pharmaceuticals (Basel)
; 14(7)2021 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34358118