Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Mais filtros

Base de dados
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
Phys Med Biol ; 65(9): 095011, 2020 05 07.
Artigo em Inglês | MEDLINE | ID: mdl-32182598

RESUMO

The IAEA is currently coordinating a multi-year project to update the TRS-398 Code of Practice for the dosimetry of external beam radiotherapy based on standards of absorbed dose to water. One major aspect of the project is the determination of new beam quality correction factors, k Q , for megavoltage photon beams consistent with developments in radiotherapy dosimetry and technology since the publication of TRS-398 in 2000. Specifically, all values must be based on, or consistent with, the key data of ICRU Report 90. Data sets obtained from Monte Carlo (MC) calculations by advanced users and measurements at primary standards laboratories have been compiled for 23 cylindrical ionization chamber types, consisting of 725 MC-calculated and 179 experimental data points. These have been used to derive consensus k Q values as a function of the beam quality index TPR20,10 with a combined standard uncertainty of 0.6%. Mean values of MC-derived chamber-specific [Formula: see text] factors for cylindrical and plane-parallel chamber types in 60Co beams have also been obtained with an estimated uncertainty of 0.4%.


Assuntos
Radioisótopos de Cobalto/análise , Método de Monte Carlo , Fótons/uso terapêutico , Radiometria/métodos , Radiometria/normas , Consenso , Humanos , Planejamento da Radioterapia Assistida por Computador , Eficiência Biológica Relativa , Incerteza
2.
Med Phys ; 46(8): 3739-3745, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31131902

RESUMO

PURPOSE: Reference dosimetry in a strong magnetic field is made more complex due to (a) the change in dose deposition and (b) the change in sensitivity of the detector. Potentially it is also influenced by thin air layers, interfaces between media, relative orientations of field, chamber and radiation, and minor variations in ion chamber stem or electrode construction. The PTW30013 and IBA FC65-G detectors are waterproof Farmer-type ion chambers that are suitable for reference dosimetry. The magnetic field correction factors have previously been determined for these chamber types. The aim of this study was to assess the chamber-to-chamber variation and determine whether generic chamber type-specific magnetic field correction factors can be applied for each of the PTW30013 and FC65-G type ion chambers when they are oriented anti-parallel (ǁ) to, or perpendicular (⊥) to, the magnetic field. METHODS: The experiment was conducted with 12 PTW30013 and 13 FC65-G chambers. The magnetic field correction factors were measured using a practical method. In this study each chamber was cross-calibrated against the local standard chamber twice; with and without magnetic field. Measurements with 1.5 T magnetic field were performed with the 7 MV FFF beam of the MRI-linac. Measurements without magnetic field (0 T) were performed with the 6 MV conventional beam of an Elekta Agility linac. A prototype MR-compatible PTW MP1 phantom was used along with a prototype holder that facilitated measurements with the chamber aligned 90° counter-clockwise (⊥) and 180° (ǁ) to the direction of the magnetic field. A monitor chamber was also mounted on the holder and all measurements were normalized so that the effect of variations in the output of each linac was minimized. Measurements with the local standard chamber were repeated during the experiment to quantify the experimental uncertainty. Recombination was measured in the 6 MV beam. Beam quality correction factors were applied. Differences in recombination and beam quality between beams are constant within each chamber type. By comparing the results for the two cross calibrations the magnetic field correction factors can be determined for each chamber, and the variation within the chamber-type determined. RESULTS: The magnetic field correction factors within both PTW30013 and FC65-G chamber-types were found to be very consistent, with observed standard deviations for the PTW30013 of 0.19% (ǁ) and 0.13% (⊥), and for the FC65-G of 0.15% (ǁ) and 0.17% (⊥). These variations are comparable with the standard uncertainty (k = 1) of 0.24%. CONCLUSION: The consistency of the results for the PTW30013 and FC65-G chambers implies that it is not necessary to derive a new factor for every new PTW30013 or FC65-G chamber. Values for each chamber-type (with careful attention to beam energy, magnetic field strength and beam-field-chamber orientations) can be applied from the literature.


Assuntos
Campos Magnéticos , Radiometria/instrumentação , Calibragem , Aceleradores de Partículas , Imagens de Fantasmas
3.
Phys Med Biol ; 53(13): 3531-42, 2008 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-18552419

RESUMO

A new water calorimeter for orthovolt x-rays has been developed at NMi. The purpose of this calorimeter is to provide calibrations in terms of absorbed dose to water. Four internationally accepted CCRI qualities (100-250 kV) have been characterized. Correction factors have been determined with measurements, Monte Carlo calculations and heat transport models. The results of the calculations have been validated against measurements. The absorbed dose to water calibration coefficient, N(Dw,WCM), with the new calorimeter has been compared to the N(Dw,NCS) based on an air-kerma calibration coefficient, using the current NCS-10 dosimetry protocol. A good agreement is found for all beam qualities where the total uncertainty (1 SD) has decreased from 2.5% for N(Dw,NCS) to better than 1.5% for N(Dw,WCM), using the new water calorimeter.


Assuntos
Calorimetria/métodos , Água/química , Raios X , Absorção , Ar , Calibragem , Calorimetria/instrumentação , Calorimetria/normas , Doses de Radiação , Radiometria/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
4.
Phys Med Biol ; 60(24): 9313-27, 2015 Dec 21.
Artigo em Inglês | MEDLINE | ID: mdl-26580846

RESUMO

With the advent of MR guided radiotherapy the relevance of Monte Carlo radiation transport simulations in the presence of strong magnetic fields (B-fields) is increasing. While new tests are available to benchmark these simulation algorithms for internal consistency, their application to known codes such as EGSnrc, PENELOPE, and GEANT4 is yet to be provided. In this paper a method is provided to apply the Fano cavity test as a benchmark for a generic implementation of B-field effects in PENELOPE. In addition, it is investigated whether violation of the conditions for the Fano test can partially explain the change in the response of ionization chambers in the presence of strong B-fields. In the present paper it is shown that the condition of isotropy of the secondary particle field (Charged Particle Isotropy, CPI) is an essential requirement to apply the Fano test in the presence of B-fields. Simulations in PENELOPE are performed with (B = 0.0 T) and (B = 1.5 T) for cylindrical cavity geometry. The secondary particle field consists of electrons generated from a mono-energetic source (E = 0.5-4.0 MeV) with a uniform source density and different angular distributions; isotropic, mono-directional, and Compton. In realistic photon fields the secondary radiation field has a non-isotropic angular distribution due to the Compton process. Based on the simulations for the Compton angular distribution (non-CPI), the response change of the cavity model in a uniform radiation field in the presence of B-fields is investigated. For the angular distributions that violate the CPI condition and B = 1.5 T, the deviations from 1 are considerable, which emphasizes the requirement of CPI. For the isotropic angular distributions obeying this requirement, both the results for B = 0.0 T and B = 1.5 T shows deviations from the predictions for E ⩾ 1.5 MeV with values up to 1.0% for E = 4.0 MeV. Nevertheless, due to the high correlation in the deviation for B = 0.0 T and B = 1.5 T, the accuracy of the PENELOPE code for the simulation of the change in detector response in the presence of B-fields is within 0.3%. The effect of the B-field on the detector response for non-isotropic angular distributions suggests that violation of CPI is a major contribution to the response change of ionization chambers in the presence of B-fields.


Assuntos
Algoritmos , Elétrons , Método de Monte Carlo , Imagens de Fantasmas , Software , Radiação Eletromagnética , Humanos , Fótons
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA