Pesquisa | BVS IEC

1.

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.

Cappelletti, Valentina; Hauser, Thomas; Piazza, Ilaria; Pepelnjak, Monika; Malinovska, Liliana; Fuhrer, Tobias; Li, Yaozong; Dörig, Christian; Boersema, Paul; Gillet, Ludovic; Grossbach, Jan; Dugourd, Aurelien; Saez-Rodriguez, Julio; Beyer, Andreas; Zamboni, Nicola; Caflisch, Amedeo; de Souza, Natalie; Picotti, Paola.

Cell ; 184(2): 545-559.e22, 2021 01 21.

Artigo em Inglês | MEDLINE | ID: mdl-33357446

2.

In situ analysis of osmolyte mechanisms of proteome thermal stabilization.

Pepelnjak, Monika; Velten, Britta; Näpflin, Nicolas; von Rosen, Tatjana; Palmiero, Umberto Capasso; Ko, Jeong Hoon; Maynard, Heather D; Arosio, Paolo; Weber-Ban, Eilika; de Souza, Natalie; Huber, Wolfgang; Picotti, Paola.

Nat Chem Biol ; 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-38424171

3.

Systematic identification of structure-specific protein-protein interactions.

Holfeld, Ales; Schuster, Dina; Sesterhenn, Fabian; Gillingham, Alison K; Stalder, Patrick; Haenseler, Walther; Barrio-Hernandez, Inigo; Ghosh, Dhiman; Vowles, Jane; Cowley, Sally A; Nagel, Luise; Khanppnavar, Basavraj; Serdiuk, Tetiana; Beltrao, Pedro; Korkhov, Volodymyr M; Munro, Sean; Riek, Roland; de Souza, Natalie; Picotti, Paola.

Mol Syst Biol ; 2024 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-38702390

4.

The Relationship Between Decision-making Capacity and the Domains of Awareness in Alzheimer Disease.

de Souza, Natalie A P; de Oliveira, Felipe; de Carvalho, Raquel L S; Dourado, Marcia C N.

Alzheimer Dis Assoc Disord ; 36(1): 58-63, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35090160

5.

A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids.

Zanotelli, Vito Rt; Leutenegger, Matthias; Lun, Xiao-Kang; Georgi, Fanny; de Souza, Natalie; Bodenmiller, Bernd.

Mol Syst Biol ; 16(12): e9798, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33369114

6.

Detecting Protein-Small Molecule Interactions Using Limited Proteolysis-Mass Spectrometry (LiP-MS).

Pepelnjak, Monika; de Souza, Natalie; Picotti, Paola.

Trends Biochem Sci ; 45(10): 919-920, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32475682

7.

A model for tumor-immune interaction.

de Souza, Natalie.

Nat Methods ; 15(10): 762, 2018 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-30275589

8.

A model gut microbiome.

de Souza, Natalie.

Nat Methods ; 15(8): 572, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-30065386

9.

Watching neurotransmission in vitro.

de Souza, Natalie.

Nat Methods ; 8(9): 708-9, 2011 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-21985002

10.

The power of 'weak' interactions.

de Souza, Natalie.

Nat Methods ; 13(1): 14, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-27110627

11.

Simple tools for difficult imaging.

de Souza, Natalie.

Nat Methods ; 13(2): 112-3, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-27243094

12.

Multiplex protein imaging in tumour biology.

de Souza, Natalie; Zhao, Shan; Bodenmiller, Bernd.

Nat Rev Cancer ; 24(3): 171-191, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38316945

13.

Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer.

Cords, Lena; Engler, Stefanie; Haberecker, Martina; Rüschoff, Jan Hendrik; Moch, Holger; de Souza, Natalie; Bodenmiller, Bernd.

Cancer Cell ; 42(3): 396-412.e5, 2024 Mar 11.

Artigo em Inglês | MEDLINE | ID: mdl-38242124

14.

Genomic dark matter: the search goes extreme.

de Souza, Natalie.

Nat Methods ; 7(6): 424, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20524216

15.

Watching single lipids move.

de Souza, Natalie.

Nat Methods ; 7(6): 428, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20524219

16.

Gene expression. Many mini mind promoters.

de Souza, Natalie.

Nat Methods ; 7(11): 870-1, 2010 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21049577

17.

Genomics. Micro-C maps of genome structure.

de Souza, Natalie.

Nat Methods ; 12(9): 812, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26554092

18.

Systems biology: an expanded human interactome.

de Souza, Natalie.

Nat Methods ; 12(2): 107, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25798472

19.

Complex regulatory control with CRISPR.

de Souza, Natalie.

Nat Methods ; 12(3): 172, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25879101

20.

Systems biology: Learning from history.

de Souza, Natalie.

Nat Methods ; 7(9): 672-3, 2010 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-20827802

BVS IEC

Instituto Evandro Chagas

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Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.

In situ analysis of osmolyte mechanisms of proteome thermal stabilization.

Systematic identification of structure-specific protein-protein interactions.

The Relationship Between Decision-making Capacity and the Domains of Awareness in Alzheimer Disease.

A quantitative analysis of the interplay of environment, neighborhood, and cell state in 3D spheroids.

Detecting Protein-Small Molecule Interactions Using Limited Proteolysis-Mass Spectrometry (LiP-MS).

A model for tumor-immune interaction.

A model gut microbiome.

Watching neurotransmission in vitro.

The power of 'weak' interactions.

Simple tools for difficult imaging.

Multiplex protein imaging in tumour biology.

Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancer.

Genomic dark matter: the search goes extreme.

Watching single lipids move.

Gene expression. Many mini mind promoters.

Genomics. Micro-C maps of genome structure.

Systems biology: an expanded human interactome.

Complex regulatory control with CRISPR.

Systems biology: Learning from history.