Detalhe da pesquisa
1.
Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema.
PLoS Genet
; 19(8): e1010609, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37585454
2.
Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.
Cell
; 143(5): 826-36, 2010 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21111240
3.
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain.
PLoS Genet
; 6(5): e1000952, 2010 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485568
4.
Kinesin-associated protein 3 (KIFAP3) has no effect on survival in a population-based cohort of ALS patients.
Proc Natl Acad Sci U S A
; 107(27): 12335-8, 2010 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20566859
5.
Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions.
J Biol Chem
; 285(51): 39922-34, 2010 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20889981
6.
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Proc Natl Acad Sci U S A
; 105(29): 10244-9, 2008 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18626009
7.
Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation.
Cell Rep
; 31(13): 107843, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610143
8.
Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease.
Neurosci Lett
; 452(1): 8-11, 2009 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19146923
9.
Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression.
Sci Rep
; 8(1): 16725, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425303
10.
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Cell Rep
; 22(3): 832-847, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29346778
11.
Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.
Nat Commun
; 7: 11295, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097852
12.
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization.
Brain Res Mol Brain Res
; 134(1): 76-83, 2005 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15790532
13.
Parkinson's disease: From human genetics to clinical trials.
Sci Transl Med
; 7(305): 205ps20, 2015 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26378242
14.
Missense variant in TREML2 protects against Alzheimer's disease.
Neurobiol Aging
; 35(6): 1510.e19-26, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24439484
15.
Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.
PLoS One
; 7(2): e31152, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22355340
16.
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation.
Nat Biotechnol
; 30(5): 453-9, 2012 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22446693
17.
Ser1292 autophosphorylation is an indicator of LRRK2 kinase activity and contributes to the cellular effects of PD mutations.
Sci Transl Med
; 4(164): 164ra161, 2012 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23241745
18.
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.
PLoS One
; 6(7): e22489, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21799870
19.
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
Nat Genet
; 43(7): 699-705, 2011 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21685912
20.
Evidence for natural antisense transcript-mediated inhibition of microRNA function.
Genome Biol
; 11(5): R56, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20507594