Migration and sustainable development.

To understand the implications of migration for sustainable development requires a comprehensive consideration of a range of population movements and their feedback across space and time. This Perspective reviews emerging science at the interface of migration studies, demography, and sustainability, focusing on consequences of migration flows for nature-society interactions including on societal outcomes such as inequality; environmental causes and consequences of involuntary displacement; and processes of cultural convergence in sustainability practices in dynamic new populations. We advance a framework that demonstrates how migration outcomes result in identifiable consequences on resources, environmental burdens and well-being, and on innovation, adaptation, and challenges for sustainability governance. We elaborate the research frontiers of migration for sustainability science, explicitly integrating the full spectrum of regular migration decisions dominated by economic motives through to involuntary displacement due to social or environmental stresses. Migration can potentially contribute to sustainability transitions when it enhances well-being while not exacerbating structural inequalities or compound uneven burdens on environmental resources.

Study on agricultural water resource utilization efficiency under the constraint of carbon emission and water pollution.

Agricultural water resource utilization efficiency in China is facing significant challenges due to the dual constraints of carbon emissions and water pollution. The inefficiency in water usage in agriculture not only impacts the sustainability of water resources but also contributes to environmental degradation through increased carbon emissions and water pollution. Agricultural water resource utilization efficiency under the constraint of carbon emission and water pollution has been a critical issue in China from 2005 to 2022. This study employs the Quantile Autoregressive Distributed Lag (QARDL) method to comprehensively assess and analyze the complex relationship that exists between agricultural water usage, carbon emissions, and water pollution. By analyzing distinct quantiles of the data distribution, the research investigates how different levels of water resource utilization efficiency relate to carbon emissions and water pollution under various conditions. The findings reveal nuanced insights into the dynamic interactions among these components within the agricultural sector. This research project focuses on the efficiency of water resource utilization in agriculture while considering the constraints of carbon emission and water pollution. Given the dynamic and time-dependent character of these components, the QARDL methodology makes it possible to get a detailed knowledge of how they interact within the framework of agriculture. The study aims to give significant insights and policy suggestions to improve agricultural practices while minimizing environmental concerns linked to carbon emissions and water pollution.

Understanding uptake of community groundwater monitoring in rural Brazil.

Resource monitoring is often cited as important for effective common pool resources management. In practice, not all monitoring interventions are successful, particularly when the resource, such as groundwater, is challenging to monitor and measure. We conducted a field experiment on groundwater monitoring in Ceará, Brazil, where communities are increasingly reliant on groundwater yet do not engage in monitoring. Despite careful implementation, uptake of monitoring within the 80 treatment communities was low. To unpack this low uptake, we conduct multimethods exploratory research. We find that uptake is less likely in communities facing high coordination costs, either within the community leadership or across the broader community. Uptake is also less likely when there are physical barriers to monitoring, when there are more substitutes for groundwater, and when there is lower variability in water availability. Our findings can inform future monitoring interventions in similar contexts worldwide.

Role of supply chain digitalization and global supply chain in decarbonization of natural resources sector supply chain.

Environmental management and decarbonization are becoming increasingly critical as industries seek sustainable development paths that align with global climate targets. As businesses aim to reduce their carbon footprint, integrating effective environmental strategies with technological advancements is essential. This necessitates a clear understanding of digital technologies and environmental policies to drive decarbonization efforts. In this context, this study explores the role of digitalization in reducing carbon emissions in the natural resources sector supply chain. Furthermore, it examines the role of supply chain mapping as a mediator in the relationship between supply chain digitalization and supply chain decarbonization efforts, providing a novel perspective on how technology can intersect to foster environmental sustainability. This research targets the metal sector supply chain, a significant contributor to global carbon emissions. The data for the study was gathered through a questionnaire administered to 246 employees from various levels of the metal industry in China. We employed Covariance-based Structural Equation Modelling (CB-SEM) using AMOs for analysis. Our results show that level digitalization of supply chain processes in the metal sector has a profound and direct impact on its supply chain decarbonization. Digital technologies facilitate more efficient resource use, improved energy efficiency, and the adoption of cleaner production methods. Importantly, the study identifies supply chain mapping as a crucial mechanism through which digitalization exerts its positive influence on decarbonization. Through detailed mapping, organizations can gain visibility over their entire supply chain, identifying carbon hotspots and opportunities for improvement that digital solutions can address. The novelty of this study lies in its systematic exploration of how supply chain mapping serves not just as a tool for transparency and efficiency but as a strategic facilitator of the beneficial impacts of digitalization on decarbonization.

Natural resources-environmental technology-ecological footprint nexus: Does natural resources rents diversification make a difference?

Researchers have shown a growing interest in investigating the environmental consequences of energy exploitation and green technologies, particularly in light of the escalating severity of climate change issues in recent times. However, these researches remain incomplete in terms of the various elements and mechanisms of impact. By assessing the novel facet of resource diversification, this study has assessed the direct and indirect effects of this feature on environmental quality. This study used the Moment quantile Regression technique to examine data from 31 OECD nations spanning the time frame of 2009-2019. The findings indicate that resource diversification has an adverse effect on environmental quality, however this effect is not homogeneously observed across all countries. Countries with favorable environmental conditions will encounter a more pronounced influence from the diversification of natural resources extraction. This study further demonstrates that expanding the variety of natural resource exploitation will amplify the negative effects of resource exploitation on environmental quality. Furthermore, the degree of environmental technology exerts a beneficial impact on environmental quality across various degrees of environmental quality. Our findings offer several insightful policies for natural resources management in the context of the ongoing industrial revolution.

Does interstate trade of agricultural products in the U.S. alleviate land and water stress?

Interregional free-trade of agricultural products is expected to transfer embodied (virtual) water from more to less water-productive regions. However, irrigation in semi-arid to arid regions may significantly push up agricultural productivity but cause local water scarcity. This may result in a puzzle: inter-regional trade may save overall water consumption but lead to more severe local water scarcity. An analogous puzzle may exist for farmland, for instance, trade may save farmland but not address farmland scarcity. To test the existence of these two important puzzles, we applied environmentally extended multi-regional input-output models to obtain the inter-regional virtual agricultural water and land transfer across 48 states of the conterminous U.S. and estimated their agricultural land and water footprints in 2017. Such a detailed analysis showed that while the land-abundant Midwestern states exported a sizable amount of virtual farmland to other densely populated areas and foreign nations, the water-stressed Western U.S. and Southwestern U.S. states, like California, Arizona, and New Mexico, exported considerable amounts of water-intensive crops such as fruits, vegetables and tree nuts to the Eastern U.S. and overseas, thus worsen the local water scarcity of those water scarce states. Our analysis highlights a critical dilemma inherent in an economic productivity-focused incentive regime: It frequently leads to increased withdrawal of scarce water. Therefore, resource scarcity rents need to be reflected in inter-regional trade with the support of local environmental policies.

How wealthy in natural resource leads environmental sustainability in developing economies? An empirical investigation.

This study investigates the impact of income generated from natural resources on environmental sustainability and analyses the moderating role of institutional quality in carbon emissions function. An extensive dataset from 61 developing nations covering the years 2000-2018 has been taken, which uses a dynamic heterogeneous panel data model. Our study follows a rigorous methodology by applying the pooled mean group estimator. An extensive examination of the impacts over the short run and long run is possible using this method. This study reveals multifaceted findings: in the short run, the effect of institutional quality and natural resources revenues on carbon emissions is insignificant, implying that such factors have a relatively minor impact. The long-term examination reveals that income derived from natural resources causes a spike in carbon emissions, which causes environmental deterioration and climate change. Strong institutional quality can significantly mitigate the adverse effects of correlation between revenues from natural resources and carbon emissions, which have been observed. The study's moderating effect of natural resources richness, which gradually reduces institutional quality's ability to reduce carbon emissions, is a crucial finding. Our study significantly advances the field of environmental economics, especially when discussing sustainable development in emerging nations with abundant natural resources. It emphasizes the delicate balance that must be struck between preserving efficient environmental governance and maximizing the richness of natural resources. Our findings underscore the crucial need for developing nations to strengthen their institutional frameworks and capacities and have substantial policy implications. These steps are essential to ensuring that the use of natural resources is in line with environmental sustainability objectives, turning resource curses into blessings for long-term development and environmental preservation. This research opens the door to sector-specific impacts and personalized policy interventions in resource-rich developing economies.

From black to green: Quantifying the impact of economic growth, resource management, and green technologies on CO2 emissions.

In an exploration of environmental concerns, this groundbreaking research delves into the relationship between GDP per capita, coal rents, forest rents, mineral rents, oil rents, natural gas rents, fossil fuels, renewables, environmental tax and environment-related technologies on CO2 emissions in 30 highly emitting countries from 1995 to 2021 using instrumental-variables regression Two-Stage least squares (IV-2SLS) regression and two-step system generalized method of moments (GMM) estimates. Our results indicate a significant positive relationship between economic growth and CO2 emissions across all quantiles, showcasing an EKC with diminishing marginal effects. Coal rents exhibit a statistically significant negative relationship with emissions, particularly in higher quantiles, and mineral rents show a negative association with CO2 emissions in lower and middle quantiles, reinforcing the idea of resource management in emissions reduction. Fossil fuels exert a considerable adverse impact on emissions, with a rising effect in progressive quantiles. Conversely, renewable energy significantly curtails CO2 emissions, with higher impacts in lower quantiles. Environmental tax also mitigates CO2 emissions. Environment-related technologies play a pivotal role in emission reduction, particularly in lower and middle quantiles, emphasizing the need for innovative solutions. These findings provide valuable insights for policymakers, highlighting the importance of tailoring interventions to different emission levels and leveraging diverse strategies for sustainable development.

Unpacking the environmental quality through the effects of natural resources, renewable energy consumption, banking development and industrial value addition: An empirical evidence from BRICS countries.

This study explores the association between natural resources rent, industrial value addition, banking development, renewable energy consumption, total reserves and environmental quality in the dynamic context of BRICS nations from 1995 to 2019. BRICS economies are responsible for global greenhouse gas emissions and confront pressing environmental challenges, including biodiversity loss and pollution. For the dependent variable, the environmental quality, the study constructed a composite index using PCA for all environmental indicators where interdependencies among variables are prevalent. Besides this, the study incorporates two interaction terms to determine the indirect influence of natural resource rent and banking development on environmental quality through the mediating role of industrial value addition. By applying the CS-ARDL technique, the outcomes of the study reveal that natural resources rent, industrial value addition, and total reserves positively influence ENQ, indicating the adverse consequences of industrial sectors on environmental quality and continued environmental degradation due to resource-intensive industrial production, underscoring the urgency of sustainable resource management. In contrast, banking development and renewable energy consumption negatively influence ENQ, signifying the positive role of developed banking sectors in supporting eco-friendly projects and enhancing environmental quality. This study offers valuable insights for policy interventions to foster a more sustainable future.

Biochemical profiling and antioxidant activity analysis of commercially relevant seaweeds from northwest Europe.

BACKGROUND: The drive towards ensuring the sustainability of bioresources has been linked with better valorising primary materials and developing biorefinery pipelines. Seaweeds constitute valuable coastal resources with applications in the bioenergy, biofertiliser, nutrition, pharmaceutical and cosmetic sectors. Owing to the various sought-after metabolites they possess, several seaweed species are commercially exploited throughout Western Europe, including Ireland. Here, four commercially relevant brown (Fucus serratus and Fucus vesiculosus) and red (Chondrus crispus and Mastocarpus stellatus) seaweed species were sampled during a spring tide in July 2021 on moderately exposed shores across three coastal regions in the west of Ireland. RESULTS: Significant regional differences were identified when specimens were analysed for carbohydrates (max. 80.3 µg glucose eq mg-1 DW), proteins (max. 431.3 µg BSA eq. mg-1 DW), lipids (max. 158.6 mg g-1 DW), pigment signature and antioxidant potential. Protein content for F. serratus recorded a twofold difference between northern and southern specimens. The antioxidant potential of F. vesiculosus and M. stellatus returned greater activity compared to F. serratus and C. crispus, respectively. Multivariate analysis showed a clear latitudinal pattern across the three western coastal regions (north, west and south) for both F. vesiculosus and F. serratus. CONCLUSION: F. vesiculosus thalli from the northwest were richer in pigment content while the F. serratus thalli from the northwest were richer in antioxidants. Such biogeographic patterns in the biochemical make-up of seaweeds need consideration for the development of regional integrated aquaculture systems and the optimisation of the biomass content for targeted downstream applications. © 2024 Society of Chemical Industry.

Oviposition behaviour in Drosophila melanogaster: Genetic and behavioural decoupling between oviposition acceptance and preference for natural fruits.

In phytophagous insects, oviposition behaviour is an important component of habitat selection and, given the multiplicity of genetic and environmental factors affecting its expression, is defined as a complex character resulting from the sum of interdependent traits. Here, we study two components of egg-laying behaviour: oviposition acceptance (OA) and oviposition preference (OP) in Drosophila melanogaster using three natural fruits as resources (grape, tomato and orange) by means of no-choice and two-choice experiments, respectively. This experimental design allowed us to show that the results obtained in two-choice assays (OP) cannot be accounted for by those resulting from no-choice assays (OA). Since the genomes of all lines used are completely sequenced, we perform a genome-wide association study to identify and characterize the genetic underpinnings of these oviposition behaviour traits. The analyses revealed different candidate genes affecting natural genetic variation of both OA and OP traits. Moreover, our results suggest behavioural and genetic decoupling between OA and OP and that egg-laying behaviour is plastic and context-dependent. Such independence in the genetic architectures of OA and OP variation may influence different aspects of oviposition behaviour, including plasticity, canalization, host shift and maintenance of genetic variability, which contributes to the adoption of adaptive strategies during habitat selection.

Integrating principles and tools of decision science into value-driven watershed planning for compensatory mitigation.

Several environmental policies strive to restore impaired ecosystems and could benefit from a consistent and transparent process-codeveloped with key stakeholders-to prioritize impaired ecosystems for restoration activities. The Clean Water Act, for example, establishes reallocation mechanisms to transfer ecosystem services from sites of disturbance to compensation sites to offset aquatic resource functions that are unavoidably lost through land development. However, planning for the prioritization of compensatory mitigation areas is often hampered by decision-making processes that fall into a myopic decision frame because they are not coproduced with stakeholders. In this study, we partnered with domain experts from the North Carolina Division of Mitigation Services to codevelop a real-world decision framework to prioritize catchments by potential for the development of mitigation projects following principles of a structured decision-making process and knowledge coproduction. Following an iterative decision analysis cycle, domain experts revised foundational components of the decision framework and progressively added complexity and realism as they gained additional insights or more information became available. Through the course of facilitated in-person and remote interactions, the codevelopment of a decision framework produced three main "breakthroughs" from the perspective of the stakeholder group: (a) recognition of the problem as a multiobjective decision driven by several values in addition to biogeophysical goals (e.g., functional uplift, restoring or enhancing lost functionality of ecosystems); (b) that the decision comprises a linked and sequential planning-to-implementation process; and (c) future risk associated with land-use and climate change must be considered. We also present an interactive tool for "on-the-fly" assessment of alternatives and tradeoff analysis, allowing domain experts to quickly test, react to, and revise prioritization strategies. The decision framework described in this study is not limited to the prioritization of compensatory mitigation activities across North Carolina but rather serves as a framework to prioritize a wide range of restoration, conservation, and resource allocation activities in similar environmental contexts across the nation.

Natural resources for sustainable synthesis of nanomaterials with anticancer applications: A move toward green nanomedicine.

Today, researchers have focused on the application of environmentally-benign and sustainable micro- and nanosystems for drug delivery and cancer therapy. Compared to conventional chemotherapeutics, advanced micro- and nanosystems designed by applying abundant, natural, and renewable feedstocks have shown biodegradability, biocompatibility, and low toxicity advantages. However, important aspects of toxicological assessments, clinical translational studies, and suitable functionalization/modification still need to be addressed. Herein, the benefits and challenges of green nanomedicine in cancer nanotherapy and targeted drug delivery are cogitated using nanomaterials designed by exploiting natural and renewable resources. The application of nanomaterials accessed from renewable natural resources, comprising metallic nanomaterials, carbon-based nanomaterials, metal-organic frameworks, natural-derived nanomaterials, etc. for targeted anticancer drug delivery and cancer nanotherapy are deliberated, with emphasis on important limitations/challenges and future perspectives.

Public participation and outgoing audit of natural resources: Evidence from tripartite evolutionary game in China.

Public participation is essential to the success of ecological civilization. Whether public participation can effectively play a role in the outgoing audit of natural resources (OANR) is an important issue that remains to be explored. This paper uses the tripartite evolutionary game to explore the mechanism of the audit subjects, the leading cadres, and the public in the OANR. The research finds that there is a two-way linkage relationship between the audit subjects and the leading cadres. The audit subjects and the leading cadres affect the behavior strategies of the public in the indirect way and direct way, respectively. However, the public lacks the path to directly affect the other two subjects. The tripartite ideal audit model of "the audit subjects conduct due diligence audits, leading cadres perform duties, the public participate" cannot be realized. The external effect of the public's strategic choice is not enough to make the profit or loss of leading cadres change structurally and then change their behaviors. This paper demonstrates the reasons why the public cannot effectively participate in the OANR at the current stage from three aspects, which are the interpretation of the equations for replication dynamics, the particularity of the audit system, and the effectiveness of public participation. Three suggestions are put forward which are encouraging citizens' indirect participation in the OANR, disclosing information about the OANR, and improving citizens' awareness of the OANR. This paper has important guiding significance for other developing countries to promote public participation in natural resource auditing.

A Novel Approach for Screening Sericin-Derived Therapeutic Peptides Using Transcriptomics and Immunoprecipitation.

With the demand for more efficient and safer therapeutic drugs, targeted therapeutic peptides are well received due to their advantages of high targeting (specificity), low immunogenicity, and minimal side effects. However, the conventional methods of screening targeted therapeutic peptides in natural proteins are tedious, time-consuming, less efficient, and require too many validation experiments, which seriously restricts the innovation and clinical development of peptide drugs. In this study, we established a novel method of screening targeted therapeutic peptides in natural proteins. We also provide details for library construction, transcription assays, receptor selection, therapeutic peptide screening, and biological activity analysis of our proposed method. This method allows us to screen the therapeutic peptides TS263 and TS1000, which have the ability to specifically promote the synthesis of the extracellular matrix. We believe that this method provides a reference for screening other drugs in natural resources, including proteins, peptides, fats, nucleic acids, and small molecules.

The outgoing audit of natural resources assets and enterprise productivity: New evidence from difference-in-differences-in-differences in China.

Despite increasing evidence documenting the role of the outgoing audit of natural resources (OANRA) in environmental governance and enterprise innovation, little is known about its impact on enterprises' total factor productivity (TFP). To address this question, we treat the OANRA policy launched in 2014 in China as a quasi-natural experiment. We adopt a difference-in-differences-in-differences (DDD) method that exploits three-dimensional variations: city (i.e., OANRA cities versus non-OANRA cities), industry (i.e., more polluting industries versus less polluting ones), and year (i.e., before and after the OANRA policy). Employing a dataset of Chinese industrial listed companies from 2012 to 2019, we reveal that after the OANRA implementation, enterprises' TFP in more polluting industries of OANRA cities decreases by 4.0%. Our mechanism analysis shows that the OANRA restrains the TFP by reducing the financing scale of enterprises and increasing environmental investment of governments. Further, the heterogeneity analysis finds the inhibitory effect of the OANRA is more prominent in large-scale and state-owned enterprises, as well as enterprises located in eastern, low fiscal pressure, and high pollutant emission cities. Our findings provide support for the neoclassical economics hypothesis that the OANRA increases enterprises' compliance costs and decreases their productivity.

Mining and Sustainability in the Circumpolar North: The Role of Government in Advancing Corporate Social Responsibility.

Corporate Social Responsibility (CSR) is recognized as important to fostering sustainable natural resource development in the Circumpolar North. Governments are playing an increasingly active role in promoting and shaping CSR initiatives, often in collaboration with Indigenous communities and industry. This paper explores the role of CSR in mining for improving socio-economic and environmental management practice. The article argues that government instituted regulations can lead to the development and implementation of CSR practices by mining companies. To examine the relationship between government requirements and CSR, we use two Northern case studies: Cameco Corporation's uranium mining operations located in Saskatchewan, Canada and Northern Iron's iron mining operation located in Troms and Finnmark county, Norway. Through an in-depth review of scholarly literature, document analysis, and semi-structured interviews, our findings suggest that the role of the state in the initiation and implementation of CSR is of much greater importance than is currently acknowledged in the literature. In the case of Cameco, the Mine Surface Lease Agreements agreed to by the corporation and the provincial government provided motivation for the development and implementation of their world-renowned CSR practices, resulting in a community-based environmental monitoring program and benefits for both the company and surrounding communities. With Northern Iron's operations in Kirkenes, working hour requirements instituted by the Norwegian Government allowed for significantly higher levels of local employment. Our findings suggest a greater role exists for government to facilitate the adoption of CSR policies, contributing in turn to improved socio-economic and environmental outcomes for Northern communities.

Antimicrobial activities of nano-emulsion of virgin coconut oil.

This study aimed to determine the nano-emulsion of virgin coconut oil (n-VCO) formula that can produce the best size and zone inhibition of antimicrobial activity. The VCO was formulated with the different percentages of Tween 80 (P1: 24%, P2: 25%, P3: 26%) and sorbitol (P1: 36%, P2: 35%, P3: 34%). The particle size of the n-VCO emulsion was observed under transmission electron microscopy (TEM). The antimicrobial activity test of the n-VCO was determined by a challenge test using Salmonella Typhi (S. Typhi), Staphylococcus aureus (S. aureus), and Escherichia coli (E. coli) bacteria. The data were analysed by a one-way ANOVA (P < 0.05). The significant data were furthermore tested by Duncan's multiple ranges (SPSS v26.0). This study showed that the P3 formulation (26% Tween 80 and 34% sorbitol) produced the best n-VCO among all the treatments showing a particle size of 5-100 nm. Formulas P1 and P2 produced particle sizes of about 500-1 000 nm. The antimicrobial test showed that the P3 formula had a strong inhibitory effect on S. Typhi (7.442 ± 0.52 mm), S. aureus (8.380 ± 0.49 mm), and E. coli (6.490 ± 0.82 mm). This study concluded that the formula of the detergent strongly influences the particle size of the n-VCO. The n-VCO has enormous potential to be used as an alternative antimicrobial.

One hundred-seventy years of stressors erode salmon fishery climate resilience in California's warming landscape.

People seek reliable natural resources despite climate change. Diverse habitats and biologies stabilize productivity against disturbances like climate, prompting arguments to promote climate-resilient resources by prioritizing complex, less-modified ecosystems. These arguments hinge on the hypothesis that simplifying and degrading ecosystems will reduce resources' climate resilience, a process liable to be cryptically evolving across landscapes and human generations, but rarely documented. Here, we examined the industrial era (post 1848) of California's Central Valley, chronicling the decline of a diversified, functional portfolio of salmon habitats and life histories and investigating for empirical evidence of lost climate resilience in its fishery. Present perspectives indicate that California's dynamic, warming climate overlaid onto its truncated, degraded habitat mosaic severely constrains its salmon fishery. We indeed found substantial climate constraints on today's fishery, but this reflected a shifted ecological baseline. During the early stages of a stressor legacy that transformed the landscape and -- often consequently -- compressed salmon life history expression, the fishery diffused impacts of dry years across a greater number of fishing years and depended less on cool spring-summer transitions. The latter are important given today's salmon habitats, salmon life histories, and resource management practices, but are vanishing with climate change while year-to-year variation in fishery performance is rising. These findings give empirical weight to the idea that human legacies influence ecosystems' climate resilience across landscapes and boundaries (e.g., land/sea). They also raise the question of whether some contemporary climate effects are recent and attributable not only to increasing climate stress, but to past and present human actions that erode resilience. In general, it is thus worth considering that management approaches that prioritize complex, less-modified ecosystems may stabilize productivity despite increasing climate stress and such protective actions may be required for some ecological services to persist into uncertain climate futures.

Exploring Marine as a Rich Source of Bioactive Peptides: Challenges and Opportunities from Marine Pharmacology.

This review highlights the underexplored potential and promises of marine bioactive peptides (MBPs) with unique structural, physicochemical, and biological activities to fight against the current and future human pathologies. A particular focus is given to the marine environment as a significant source to obtain or extract high-value MBPs from touched/untouched sources. For instance, marine microorganisms, including microalgae, bacteria, fungi, and marine polysaccharides, are considered prolific sources of amino acids at large, and peptides/polypeptides in particular, with fundamental structural sequence and functional entities of a carboxyl group, amine, hydrogen, and a variety of R groups. Thus, MBPs with tunable features, both structural and functional entities, along with bioactive traits of clinical and therapeutic value, are of ultimate interest to reinforce biomedical settings in the 21st century. On the other front, as the largest biome globally, the marine biome is the so-called "epitome of untouched or underexploited natural resources" and a considerable source with significant potentialities. Therefore, considering their biological and biomedical importance, researchers around the globe are redirecting and/or regaining their interests in valorizing the marine biome-based MBPs. This review focuses on the widespread bioactivities of MBPs, FDA-approved MBPs in the market, sustainable development goals (SDGs), and legislation to valorize marine biome to underlying the impact role of bioactive elements with the related pathways. Finally, a detailed overview of current challenges, conclusions, and future perspectives is also given to satisfy the stimulating demands of the pharmaceutical sector of the modern world.