Disadvantaged group members are prouder of their group when using the language of the dominant group compared to their native language.

In ethnically and linguistically diverse societies, disadvantaged groups often face pressures to acquire and speak the advantaged group's language to achieve social inclusion and economic mobility. This work investigates how using the advantaged group's language affects disadvantaged group members' in-group pride and collective self-esteem, relative to using their native language. Across six experimental studies involving Palestinian citizens of Israel (total N = 1,348), we test two competing hypotheses: Disadvantaged group members may experience greater in-group pride when using a) their native language, due to its emotional significance (the nativity hypothesis), or b) the language of the advantaged group, due to activation of habituated compensatory responses to dominance relations (the identity enhancement hypothesis). We found that respondents reported significantly higher in-group pride when responding to a Hebrew survey when compared to performing the same activity in Arabic (Studies 1a and 1b), regardless of whether the researchers administering the survey were identified as Jewish or Arab (Studies 2a and 2b). Study 3 replicated this effect while employing the "bogus pipeline" technique, suggesting the pride expression was authentic, not merely driven by social desirability. Finally, Study 4 (pre-registered) examined additional measures of positive regard for the in-group, finding that participants described their group more positively in an attribute selection task, and reported greater collective self-esteem, when surveyed in Hebrew, rather than in Arabic. Taken together, these findings suggest that language use influences disadvantaged group members' perceptions and feelings concerning their group when those languages are associated with relative position in an intergroup hierarchy.

Tissue proteomics repositories for data reanalysis.

We are approaching the third decade since the establishment of the very first proteomics repositories back in the mid-'00s. New experimental approaches and technologies continuously enrich the field while producing vast amounts of mass spectrometry data. Together with initiatives to establish standard terminology and file formats, proteomics is rapidly transforming into a mature component of systems biology. Here we describe the ProteomeXchange consortium repositories. We specifically search, collect and evaluate public human tissue datasets (categorized as "complete" by the repository) submitted in 2015-2022, to both map the existing information and assess the data set reusability. Human tissue data are variably represented in the repositories reviewed, ranging between 10% and 25% of the total data submitted, with cancers being the most represented, followed by neuronal and cardiovascular diseases. About half of the retrieved data sets were found to lack annotations or metadata necessary to directly replicate the analysis. This poses a rough challenge to data reusability and highlights the need to increase awareness of the mage-tab file format for metadata in the community. Overall, proteomics repositories have evolved greatly over the past 7 years, as they have grown in size and become equipped with various powerful applications and tools that enable data searching and analytical tasks. However, to make the most of this potential, priority must be given to finding ways to secure detailed metadata for each submission, which is likely the next major milestone for proteomics repositories.

Pride: The Emotional Foundation of Social Rank Attainment.

Pride is a self-conscious emotion, comprised of two distinct facets known as authentic and hubristic pride, and associated with a cross-culturally recognized nonverbal expression. Authentic pride involves feelings of accomplishment and confidence and promotes prosocial behaviors, whereas hubristic pride involves feelings of arrogance and conceit and promotes antisociality. Each facet of pride, we argue, contributes to a distinct means of attaining social rank: Authentic pride seems to promote prestige-a rank based on earned respect-whereas hubristic pride seems to promote dominance-a rank based on aggression and coercion. Both prestige and dominance are effective routes to power and influence in human groups, so both facets of pride are likely to be functional adaptations. Overall, the reviewed research suggests that pride is likely to be a human universal, critical for social relationships and rank attainment across human societies.

How does it feel to be greedy? The role of pride in avaricious acquisition.

BACKGROUND: Psychologists define greed as a desire to acquire more and the dissatisfaction of never having enough, but studies have not examined the psychological processes that underlie and sustain this disposition. We propose that a desire to attain pride might be one emotional mechanism that promotes greedy acquisition. In this account, greedy people experience a boost of pride from acquisition but these feelings are short-lived, potentially leading to the perpetual acquisitiveness characteristic of dispositional greed. METHOD: Four studies (including one reported in the SOM due to space limitations) using correlational, longitudinal, and daily-diary methods (N = 1778) test hypotheses about how individuals high in dispositional greed respond emotionally to new acquisitions, both when they occur and several weeks later. RESULTS: Greedy people experience heightened feelings of authentic pride in response to new acquisitions, but these feelings quickly fade. This pattern is distinct to authentic pride and not attributable to shared variance with positive affect. Greedy people also feel elevated hubristic pride in response to acquisitions, but this seems to be part of a dispositional tendency observed in response to a range of events. CONCLUSIONS: These studies provide a new understanding of a psychological process that is associated with, and could partially explain, greedy acquisition.

Who expresses their pride when? The regulation of pride expressions as a function of self-monitoring and social context.

Pride expressions draw attention to one's achievement, and therefore can enhance one's status. However, such attention has been linked to negative interpersonal consequences (i.e. envy). Fortunately, people have been found to regulate their pride expressions accordingly. Specifically, pride expressions are lower when the domain of the achievement is of high relevance to observers. We set out to replicate this effect in a non-Western sample. Additionally, we extended the current finding by investigating the moderating role of self-monitoring, an individual's ability and willingness to adjust their behaviours under different social contexts to cultivate status. This allows us to explore the previously assumed underlying status motive in regulating pride expressions. Data from two preregistered studies (N1 = 913; N2 = 1081) replicated the effect that pride expressions are inhibited when the achievement domain is relevant. A significant main effect of self-monitoring was found, such that high self-monitors express more pride than low self-monitors, consistent with the conceptualisation of self-monitoring as rooted within a status-enhancement motive. The assumed interaction effect between domain relevance and self-monitoring was not significant. Our findings suggest that the effect of domain relevance on pride expression is robust and status driven.

The effects of nonverbal pride and skill on judgements of victory and social influence: a boxing study.

Displaying nonverbal pride after a boxing match leads to judgements of success. However, it is not clear the extent to which this effect generalises nor whether it can override competing information. An experimental design had 214 participants watch two boxing clips that were manipulated so that one was evenly matched and the other had a fighter with an advantage (i.e. demonstrating more skill). Nonverbal behaviour at the completion of the fight varied between fighters (pride versus neutral). When the fight was evenly matched, the fighters displaying nonverbal pride were judged as winning the fight, but the fighter did not garner increased social influence. In contrast, when fighters demonstrated superior skill, the more skilled fighters who displayed neutral postures rather than the less-skilled ones displaying pride were judged as winning the fight, and the skilled fighters garnered increased social influence. These results suggest that in a boxing context, a pride bias works in evenly matched scenarios, but when differences in skill are more clearly present, a skill bias is more pronounced and leads to more social influence. Furthermore, perceptions of skill were associated with judgments of victory across stimuli, suggesting the importance of skill perceptions in such judgments.

Pride and moral disengagement: associations among comparison-based pride, moral disengagement, and unethical decision-making.

Pride has rarely been explored in the context of moral disengagement and unethical decision-making. Although some research has examined the associations between "authentic" and "hubristic" pride and unethical behaviour, little attention has been paid to potential mechanisms. Across two correlational studies (N = 379), we explore the associations between two facets of pride rooted on comparisons - social comparison-based pride, and self-based pride, moral disengagement, and unethical decision-making. Results show that social comparison-based pride consistently (positively) relates to moral disengagement, and that moral disengagement accounts for the association between social comparison-based pride and unethical decision-making. In sum, our findings contribute in novel ways to the understanding of how pride based in different comparison frames may lead to antisocial decision-making.

Mexican-Origin Children's Trajectories of Ethnic-Racial Pride from Childhood through Emerging Adulthood: Associations with Mothers and Fathers' Trajectories.

Ethnic-racial pride (positive feelings about one's ethnic-racial group) is critical to healthy identity development across the lifespan. Research on ethnic-racial pride development among Latinx populations has focused exclusively on youth, without regard to pride development amongst parents and relations between pride within family units. Using multivariate Latent Growth Curve Modelling among 674 Mexican-origin youth and their parents (673 mothers; 437 fathers), the trajectory of youth's pride from 5th grade through emerging adulthood (14 years/12 waves of data) as well as relations with parental pride trajectories were examined. Respondents' pride generally decreased from waves 1 to 7 (~age 11-17 in youth) and increased after wave 7. Youth's and mothers' trajectories were unrelated, but complex associations emerged between youth's and fathers' trajectories. This study supports the dynamic nature of ethnic-racial pride across distinct life stages and underscores the complex interplay of youth and parental pride trajectories, emphasizing the pivotal role parents may play in co-shaping identity development alongside their children.

Adherence to prescription medication during pregnancy: Do pregnant women use pharmacological treatment as prescribed?

AIMS: Pregnant women are hypothesized to have low adherence to prescribed medication, because of concerns about harmful effects on the unborn child. However, very little is known about the actual adherence to prescribed medication during pregnancy. We determined to what extent women follow treatment recommendations regarding prescribed medication use in mid-pregnancy. METHODS: Dutch women participating in the PRIDE Study completed a 6-week diary on medication use. Additionally, pharmacy records were obtained. For each medication dispensed, we determined 3 measures of adherence: (i) whether use was reported in the diary (actual use); (ii) difference between dispensing date and date of first reported use (initiation time); and (iii) proportion of days with at least the correct number of doses taken (implementation adherence). RESULTS: During the 6-week study period, 235 of 816 women (29%) were dispensed medication. Actual use was highest for medications used for chronic conditions (88%; 95% confidence interval [95% CI] 81-93), followed by medication for pregnancy-related conditions (79%; 95% CI 71-86) and medication for occasional and short-time use (69%; 95% CI 60-77). We observed a ≥1-day delay in treatment initiation for 42% of medications dispensed for the first time in the study period. Mean implementation adherence was 74.2% (95% CI 69.3-79.2) for medications that were actually used. CONCLUSION: Although actual use of medications dispensed was high, many pregnant women did not adhere to treatment recommendations. This nonadherence may impact maternal and child health and lead to overestimation of medication use in studies in perinatal pharmacoepidemiology relying on administrative databases.

Self-other agreement and criterion-related validity of moral pride and hubris.

OBJECTIVES: This research investigates the moral implications of trait-level moral pride and hubris, addressing prior limitations by gathering data from multiple sources. We raise two interrelated questions: (1) Do well-acquainted peers agree with their friends on judgments of trait-level moral pride and hubris? (2) Are moral pride and hubris related to divergent (im)moral outcomes, regardless of measurement sources? METHOD: We collected data from a sample of university students and their friends (N = 173 dyads) in Hong Kong to examine self-other agreement and criterion-related validity of trait-level moral pride and hubris. RESULTS: Our findings reveal a medium-to-large level of self-other agreement for, as well as a moral divergence of, trait-level moral pride and hubris. Notably, self-reports of moral pride predict prosocial behavior, whereas self-reports of moral hubris predict virtue-signaling behavior, regardless of whether the outcomes are self- or other-reported. Moreover, self-reports trump other-reports in predicting some outcomes, but the reverse is true for other outcomes. CONCLUSIONS: Our findings suggest that individuals' proneness to experience morally specific pride and hubris constitutes "real" traits, evoking divergent (im)moral outcomes. Furthermore, self- and other-reports each contain some unique trait-relevant information, with their relative predictive power depending on the specific predictor and outcome.

(Extra) ordinary parenting: Parents of children with disabilities in the context of disability stigma and pride.

INTRODUCTION/BACKGROUND: The research focuses primarily on how parents construct images of themselves and their children that diverge from the narrative of disability as a life tragedy and focus on emphasizing dignity and self-esteem. METHODS: The research was qualitative. A technique of an unstructured interview conducted with parents of people with intellectual disabilities was used to collect data. The analysis and interpretation were based on the procedures of the grounded theory. RESULTS AND CONCLUSION: Parents talk about their children as a source of pride, pointing to positive social experiences, social relationships and interactions in the public sphere. At the same time, parents emphasized the painful and exhausting experience of dealing with various types of institutions, thus highlighting the negative role of stigma in their lives and those of their children. Parents resisted framing their children's 'deficits' and their own lives in terms of mere tragedy or misfortune.

Anton Boisen Reconsidered: Psychiatric Survivor and Mad Prophet.

Anton Boisen was a seminal figure in the psychology of religion and pastoral psychology, but scholars have remained skeptical about his theoretical contributions and have perpetuated the stigma surrounding his psychiatric diagnosis and incarceration. I argue that Boisen was a prophet, ahead of his time, and that the academy has been slow to hear his salient critiques of the psychiatric system, and his contention that "psychosis" and "mystical experience" are overlapping phenomena. Most significantly, scholars have ignored the kernel of prophetic truth in Boisen's own visionary experience, which, remarkably, in 1920, predicted the ecological crisis of our current age. Reclaiming Boisen's unique voice might help us reclaim the uniqueness of the disciplines he helped birth.

A Comprehensive Evaluation of Consensus Spectrum Generation Methods in Proteomics.

Spectrum clustering is a powerful strategy to minimize redundant mass spectra by grouping them based on similarity, with the aim of forming groups of mass spectra from the same repeatedly measured analytes. Each such group of near-identical spectra can be represented by its so-called consensus spectrum for downstream processing. Although several algorithms for spectrum clustering have been adequately benchmarked and tested, the influence of the consensus spectrum generation step is rarely evaluated. Here, we present an implementation and benchmark of common consensus spectrum algorithms, including spectrum averaging, spectrum binning, the most similar spectrum, and the best-identified spectrum. We have analyzed diverse public data sets using two different clustering algorithms (spectra-cluster and MaRaCluster) to evaluate how the consensus spectrum generation procedure influences downstream peptide identification. The BEST and BIN methods were found the most reliable methods for consensus spectrum generation, including for data sets with post-translational modifications (PTM) such as phosphorylation. All source code and data of the present study are freely available on GitHub at https://github.com/statisticalbiotechnology/representative-spectra-benchmark.

Comparing gratitude and pride: evidence from brain and behavior.

Gratitude and pride are both positive emotions. Yet gratitude motivates people to help others and build up relationships, whereas pride motivates people to pursue achievements and build on self-esteem. Although these social outcomes are crucial for humans to be evolutionarily adaptive, no study so far has systematically compared gratitude and pride to understand why and how they can motivate humans differently. In this review, we compared gratitude and pride from their etymologies, cognitive prerequisites, motivational functions, and brain regions involved. By integrating the evidence from brain and behavior, we suggest that gratitude and pride share a common reward basis, yet gratitude is more related to theory of mind, while pride is more related to self-referential processing. Moreover, we proposed a cognitive neuroscientific model to explain the dynamics in gratitude and pride under a reinforcement learning framework.

Your pride is my goal: How the exposure to others' positive emotional experience influences preschoolers' delay of gratification.

This research examined whether priming very young children with a specific positive emotion would enhance their pursuit of the goal associated with that emotion. Specifically, we focused on the influence of two distinct positive emotions-pride and joy, each of which is associated with a distinct type of goal (long-term and short-term goals, respectively)-on child delay of gratification (DoG). DoG is a specific form of self-regulation that requires forgoing an immediately desired goal for the sake of a larger delayed goal. We examined whether this influence exists among preschool-aged children, an age at which emotion-related and self-regulation abilities are still developing. Across two experiments, preschoolers heard a story about another child's emotional experience of either pride or joy and then completed a DoG task. Experiment 2 was a replication of Experiment 1 using a different set of emotional scenarios. As predicted, pride-primed children showed a greater preference for larger delayed rewards over smaller immediate rewards, demonstrating enhanced DoG abilities compared with joy-primed children. These findings imply that the motivational components underlying discrete positive emotions (as well as the associations between emotions and goal pursuits) are integral to children's emotional processes. Furthermore, our findings suggest that these emotional processes influence behavior even among very young children who have not yet fully developed the relevant abilities.

Proud to help when i should: Children's positive emotions following sharing decisions with a needy versus not-needy other.

We examined children's distinct positive emotions (pride vs. joy) following sharing decisions while manipulating the recipient's neediness. Whereas both emotions are positive and desirable, pride is experienced when adhering to social goals and expectations. Therefore, we hypothesized that, with age, as children become more aware of their society's norms and internalize them, pride would be more positively related to sharing situations that highlight social norms and expectations (i.e., sharing with a poor child). We examined this hypothesis between two age groups (7-9 and 10-12 years) while assessing children's predictions of others' emotions following a decision to share in hypothetical scenarios (Study 1) and their self-reports following actual sharing decisions (Study 2). We found that older children (10-12 years), but not younger children (7-9 years), predicted more intense pride for protagonists who had decided to share their endowment with a needy other (recipient in poverty) than with a not-needy other. This effect was mediated by older children's perception of the motivation to share with a needy other (what one should do). A similar pattern was found for overall positive feelings (pride and joy) in children's self-reports following an actual sharing decision.

Prospective relationships between stigma, mental health, and resilience in a multi-city cohort of transgender and nonbinary individuals in the United States, 2016-2019.

PURPOSE: Gender-based stigma is a fundamental cause of mental health disparities among transgender and non-binary (TGNB) individuals, while resilience factors may be protective. We examined prospective relationships between gender-based enacted stigma, psychological distress, and resilience factors among TGNB individuals. METHODS: Between 2016 and 2017, we enrolled 330 TGNB individuals in three metropolitan areas in the U.S. in a prospective cohort study focused on gender identity development, risk, and resilience across the lifespan. Using multilevel regression, we examined prospective associations between enacted gender-based stigma and psychological distress (measured by the Global Severity Index/BSI-18), and examined transgender pride and social support as moderators, adjusting for age, sex assigned at birth, race/ethnicity, education, and income. RESULTS: Our sample was diverse in age (M = 34.4, range 16-87) and race/ethnicity (56.4% non-White). Over 2 years of follow-up, there was a decrease in reported gender-based stigma (b = - 0.61, p < 0.001) and transgender pride (b = - 0.14, p = 0.003), increase in social support (b = 0.21, p < 0.001), and no change in psychological distress. In adjusted analyses, gender-based stigma was positively associated with psychological distress (b = 1.10, p < 0.001) and social support was negatively associated with psychological distress (b = - 2.60, p < 0.001). Transgender pride moderated the relationship between stigma and psychological distress (p < 0.01), such that the association was stronger for lower levels of transgender pride. CONCLUSIONS: Our study provides longitudinal evidence for the deleterious role of gender-based stigma among TGNB individuals. Future interventions should consider fostering transgender pride and social support to promote mental health and mitigate negative effects of gender-based stigma.

Gefitinib induced Pemphigus Vulgaris with PRIDE complex.

Introduction: Pemphigus Vulgaris is a rare, noncommunicable, non-hereditary fatal autoimmune dermatological manifestation in which a painful blister initiates from the oral cavity. PRIDE complex stands for Papulopustules or paronychia, regulatory abnormality of hair and nails, itching, and dryness due to inhibition of EGFR. Both of these mucocutaneous manifestations are rare and are often caused by drugs. Case report: Our case reports 53-year-old patient presented with multiple crusted plaques, multiple hyperpigmented macules to patches, Solitary fluid-filled lesions on several parts of the body, and numerous erosions positive over buccal mucosa on initial follow up which was diagnosed as Pemphigus Vulgaris with PRIDE complex induced by Gefitinib. Management and outcome: The patient was treated with almost all possible treatment options, i.e., both steroids plus adjuvant therapy for pemphigus and antihistaminic, antibiotics, moisturizer, and lotions for PRIDE complex. The patient was initially admitted for infusion of the first dose of rituximab and later for management of flare-up condition and infusion of the second dose of rituximab infusion. Discussion: The complexity of the management of Pemphigus Vulgaris and PRIDE complex demands adequate monitoring of the patient's anti-cancerous therapy by clinical pharmacists, which can impact the clinical outcomes by providing pharmaceutical care and minimize the economic burden.

Associations between maternal awakening salivary cortisol levels in mid-pregnancy and adverse birth outcomes.

PURPOSE: Elevated levels of maternal cortisol have been hypothesized as the intermediate process between symptoms of depression and psychosocial stress during pregnancy and adverse birth outcomes. Therefore, we examined associations between cortisol levels in the second trimester of pregnancy and risks of three common birth outcomes in a nested case-control study. METHODS: This study was embedded in the PRIDE Study (n = 3,019), from which we selected all cases with preterm birth (n = 64), low birth weight (n = 49), and small-for-gestational age (SGA; n = 65), and 260 randomly selected controls, among the participants who provided a single awakening saliva sample in approximately gestational week 19 in 2012-2016. Multivariable linear and logistic regression was performed to assess the associations between continuous and categorized cortisol levels and the selected outcomes. RESULTS: We did not observe any associations between maternal cortisol levels and preterm birth and low birth weight. However, high cortisol levels (≥ 90th percentile) seemed to be associated with SGA (adjusted odds ratio 2.1, 95% confidence interval 0.9-4.8), in particular among girls (adjusted odds ratio 3.7, 95% confidence interval 1.1-11.9, based on eight exposed cases) in an exploratory analysis. CONCLUSION: The results of this study showed no suggestions of associations between maternal awakening cortisol levels in mid-pregnancy and adverse birth outcomes, except for an increased risk of SGA.

Examining Pride Cups as a health promotion resource to address homophobia in Australian men's sport.

Effective interventions are needed to stop homophobic behaviours in sport settings as these behaviours are associated with negative health and social outcomes for individuals who identify as Lesbian, Gay, Bisexual, Transgender, Queer or other diverse genders and sexualities. This paper reports the results of a quasi-experimental study commissioned by a public health agency to explore the benefits of a novel intervention that has been widely adopted by Australian community sport clubs. The 'Pride Cup' intervention includes education for club leaders, sport participants and the hosting of a rainbow-themed 'pride game'. Survey responses of male participants from six randomly selected sport clubs which had received the intervention (n = 148) were compared to responses (n = 137) from six randomly selected comparison clubs (Australian Football, cricket, field hockey, roller derby). Employing a post-test-only design, the study explored differences in homophobic attitudes, behaviours and individual efficacy to react negatively to homophobic behaviours. The study found significant differences (p < 0.001) in self-reported use of homophobic slurs (e.g. fag) in the last 2 weeks by participants in the treatment (11%) versus comparison (31.8%) clubs, and significant differences in the perceived use of these slurs by teammates (25.9% vs. 56.6%) or coaches (7.8% vs. 23.3%). There were also significant differences in efficacy scores, but no differences in homophobic attitudes. These results, combined with evidence of community-driven adoption, support the allocation of public health resources to conduct larger scale trials using pre/post designs to confirm these findings.

Homophobic behaviours are harmful to Lesbian, Gay, Bisexual, Transgender, Queer or other diverse genders and sexualities (LGBTQ+) people. United Nations agencies have called for research to identify ways to protect this population from discrimination in community settings. Little research has been conducted to understand how to address this problem in male sport. This study explored the value of an intervention developed by Pride Cup Australia, widely adopted by Australian community sport clubs. The charity provides education and helps clubs host a rainbow-themed 'pride game'. The study compared the homophobic language used by male participants at six clubs that had implemented a Pride Cup, with participants at six clubs which had not. Homophobic attitudes and confidence to react negatively to homophobia were also compared. Participants at clubs that adopted the intervention used less homophobic language in the previous 2 weeks than at the comparison clubs (11% vs. 31.8%) and were half as likely to report their teammates had used this language (25.9% vs. 56.6%). It is unclear if differences were caused by the Pride Cup intervention or some other factor (i.e. teams that agreed to host Pride Cup were already more supportive of LGBTQ+). Given grassroots support for this potentially promising intervention, larger scale studies are needed to confirm these findings.