The Influence of Personality Disorder Symptoms on Treatment Outcomes in Bipolar Disorder: A Secondary Analysis of a Randomised Controlled Trial: L'influence des symptômes du trouble de la personnalité sur les résultats du traitement dans le trouble bipolaire : Une analyse secondaire d'un essai randomisé contrôlé.

OBJECTIVES: Many people who are diagnosed with bipolar disorder also have comorbid personality disorder. Few studies have explored how personality disorder may influence pharmacological treatment outcomes. The aim of this study was to conduct a secondary analysis of data from a clinical trial of adjunctive nutraceutical treatments for bipolar depression, to determine whether maladaptive personality traits influence treatment outcomes. METHODS: Scores on the Standardised Assessment of Personality - Abbreviated Scale screener were used to classify participants as having bipolar disorder with (n = 119) and without (n = 29) above threshold personality disorder symptoms (personality disorder). Outcome measures included: The Montgomery Åsberg Depression Rating Scale, Clinical Global Impressions and Improvement Severity Scales, Patient Global Impressions-Improvement scale, Bipolar Depression Rating Scale, Range of Impaired Functioning Tool, Social and Occupational Functioning Assessment Scale and Quality of Life and Enjoyment Scale (Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form). Generalised estimated equations examined the two-way interactions of personality disorder by time or treatment and investigated personality disorder as a non-specified predictor of outcomes. RESULTS: Over time, the Patient Global Impressions-Improvement scores were significantly higher in those in the personality disorder group. No other significant differences in the two-way interactions of personality disorder by treatment group or personality disorder by time were found. Personality disorder was a significant but non-specific predictor of poorer outcomes on the Bipolar Depression Rating Scale, Range of Impaired Functioning Tool, and Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form, regardless of time or treatment group. CONCLUSIONS: This study highlights the potential impact of maladaptive personality traits on treatment outcomes and suggests that the presence of comorbid personality disorder may confer additional burden and compromise treatment outcomes. This warrants further investigation as does the corroboration of these exploratory findings. This is important because understanding the impact of comorbid personality disorder on bipolar disorder may enable the development of effective psychological and pharmacotherapeutic options for personalised treatments.

[Impact of the diagnostic method for borderline personality disorder on the acute response and the risk of early relapse in major depressed individuals treated with ECT: A systematic literature review]. / Impact de la méthode diagnostique du trouble de personnalité borderline sur la réponse aiguë et le risque de rechute précoce chez les individus déprimés majeurs traités par ECT : une revue systématique de la littérature.

INTRODUCTION: Given the contradictory data available in the literature, the aim of this systematic review was to investigate the impact of the diagnostic method for borderline personality disorder (BPD) on the acute response and the risk of early relapse in major depressed individuals treated with electroconvulsive therapy (ECT). METHOD: After a systematic literature review performed during March 2023 in the PubMed-Medline database according to the PRISMA criteria, 47 articles were identified using the keyword algorithm ("Electroconvulsive Therapy" [Mesh] or electroconvulsive therapy) and ("Borderline Personality Disorder" [Mesh] or borderline personality disorder). The inclusion criteria applied for the selection of articles in this systematic review were: (1) articles investigating the impact of BPD on the acute response and/or the risk of early relapse in major depressed individuals (> 18 years old) treated with ECT, (2) diagnosis of BPD and major depressive disorder by validated screening tests and/or systematic psychiatric interviews based on diagnostic criteria of international classification, (3) any type of study (cross-sectional, longitudinal, prospective, retrospective, interventional and experimental), (4) articles written in English or French, and (5) articles published after January 2000. After assessment of the 47 articles based on these inclusion criteria by two authors, seven studies investigating the impact of BPD diagnosed by systematic psychiatric interview or screening tests on the acute response and the risk of early relapse in major depressed individuals treated with ECT were included in this systematic review. RESULTS: Unlike the three studies diagnosing BPD by screening tests, the four studies diagnosing BPD by systematic psychiatric interview demonstrated a negative impact of this personality disorder on the acute response or the risk of early relapse in major depressed individuals treated with ECT. However, all studies included in this systematic review presented a low level of scientific evidence (cross-sectional epidemiological studies and retrospective cohort studies). CONCLUSION: Despite the need for studies of better scientific quality, the results of this systematic review seem to indicate that screening for BPD by systematic psychiatric interview during the pre-ECT assessment and the establishment of adequate therapeutic strategies in case of comorbid BPD could be promising options to allow better acute response and better prevention of early relapses in major depressed individuals treated with ECT.

Reflective functioning and mother-infant relationships among mothers with Borderline Personality Disorder post-therapy.

The stressful nature of parenting infants exacerbates the characteristics of Borderline Personality Disorder (BPD). Consequently, mothers with BPD tend to be emotionally dysregulated, respond impulsively to their infants, and have poorer mother-infant relationships. Few parenting interventions target the specific skill deficits observed in mothers with BPD. This study explored the differences in parental reflective functioning (PRF) and mother-infant relationship quality at baseline and following a 24-week, group parenting intervention for mothers with BPD. PRF and mother-infant relationship quality were assessed from quantitative (N = 23) and qualitative (N = 32) perspectives. Quantitative data (Parental Reflective Functioning Questionnaire) showed a significant improvement in one of the three subscales, Interest and Curiosity, between baseline and post-intervention, and a significant moderate positive association between the subscale Certainty of Mental States and maternal-infant interaction quality post-intervention. Improvements in mother-infant relationship quality were not evident from the observational measure, Nursing Child Assessment Satellite Teaching scale. In contrast, semi-structured interview qualitative data found maternal improvements in parental reflection, coping strategies implemented post-intervention, and quality of mother-infant relationships. Overwhelmingly positive intervention feedback suggested perceived maternal benefits of group format and skills taught. Future studies with larger sample sizes would allow further clarification of such parenting interventions for mothers with BPD.

La naturaleza estresante de criar infantes agudiza las características del Trastorno Límite de la Personalidad (BPD). Por tanto, madres con BPD tienden a estar emocionalmente no reguladas, responder impulsivamente a sus infantes y tener relaciones madre-infante de menor calidad. Pocas intervenciones de crianza se centran en los específicos déficits de habilidades observados en madres con BPD. El presente estudio exploró diferencias en el funcionamiento con reflexión del progenitor y la calidad de la relación madre-infante al punto inicial y al del seguimiento a 24 semanas de la intervención de crianza en grupo para madres con BPD. Se evaluó el funcionamiento con reflexión del progenitor y la relación madre-infante desde la perspectiva cuantitativa (N=23) y cualitativa (N=32). Datos cuantitativos (Cuestionario del Funcionamiento con Reflexión del Progenitor) mostraron un significativo adelanto en una de tres subescalas, Interés y Curiosidad, entre el punto inicial y posterior a la intervención, y una significativa moderada asociación positiva entre la subescala Certeza de Estados Mentales y la calidad de la interacción materno-infantil al momento posterior a la intervención. Las mejoras en la calidad de la relación madre-infante no fueron evidentes con la medida de observación, la escala de la Enseñanza Satélite de Evaluación del Niño Lactante. En contraste, datos cualitativos de entrevista semiestructurada encontraron mejoras maternas en la reflexión del progenitor, estrategias de cómo arreglárselas puestas en práctica después de la intervención, y en la calidad de las relaciones madre-infante. La abrumadoramente positiva información sobre la intervención sugirió que había una percepción materna de beneficios del formato de grupo y las habilidades que se enseñaban. Estudios futuros con grupos mayores permitirán clarificaciones adicionales de tales intervenciones de crianza para madres con BPD.

La nature stressante du parentage des nourrissons exacerbe les caractéristiques du Trouble de la Personnalité Limite (TPL). Par conséquent les mères avec un TPL ont tendance à être émotionnellement dérégulées, réagissant de manière impulsive à leurs bébés et ont des relations mère-bébé moins bonnes. Peu d'interventions de parentage visent les déficits de compétence spécifiques qui sont observés chez les mères avec un TPL. Cette étude a exploré les différences qu'on trouve dans le fonctionnement de réflexion parental et la qualité de la relation mère-bébé au départ et après une intervention de groupe de parentage pour des mères avec un TPL, de 24 semaines. Le fonctionnement parental de réflexion et la qualité de la relation mère-bébé ont été évalués à partir de perspectives quantitatives (N=23) et qualitatives (N=32). Les données quantitatives (Questionnaire de Fonctionnement de Réflexion parental ont montré une amélioration importante dans l'une des trois sous-échelles, Intérêt et Curiosité, entre le départ de l'intervention et la post-intervention, ainsi qu'un lien positive modéré important entre la sous-échelles Certitude des Etats Mentaux et la qualité de l'interaction maternelle-bébé après l'intervention. On n'a pas trouvé d'améliorations de la qualité de la relation mère-bébé à partir de la mesure d'observation échelle d'Formation Satellite de l'Evaluation du Nourrisson. Par contre les données qualitatives de l'entretien semi-structuré a révélé des améliorations maternelles dans la réflexion parentale, dans des stratégies d'adaptation mises en place après l'intervention et dans la qualité des relations mère-bébé. Les retours de l'intervention extrêmement positifs ont suggéré que des bénéfices maternels perçus du format de groupe et des compétences enseignées. Des études avec des échantillons plus grands permettraient une clarification plus poussée sur de telles interventions avec des mères avec un TPL.

A reliable instrument for making use of an overly neglected source of information on personality: The French adaptation of the Big Five Inventory-2 (Bfi-2) informant-report form.

OBJECTIVES: The assessment of personality traits is most often based on self-report. However, a growing body of research has shown that informant-report is a valuable and too often overlooked source of unique information. The aim of this study was to validate the French version of the informant-report form of the Big Five Inventory-2 (BFI-2) which assesses 15 facet traits in addition to the five major trait domains. METHODS: We asked 699 psychology and sports science and technology students to describe a person they knew well using the BFI-2 and obtained 661 valid records with demographic information. The data were analyzed using a bi-factor exploratory structural equation model with five bifactors corresponding to the Big Five domains, and three group factors (facets) each. RESULTS: This model had an excellent overall fit. Cronbach's alpha coefficients for the five domains were very satisfactory and the McDonald's omega coefficients were even better. The scales that measured the five major factors were therefore highly reliable, although Extraversion was somewhat less so. The scales measuring facets all had high reliability as measures of the whole formed by the major factor and the group factor. In addition, ten of them were reliable measures of their specific factor, and the remaining five appeared to be pure measures of the five domains. CONCLUSIONS: The informant-report form of the BFI-2 is a reliable instrument which is easy and quick to administer. These qualities should enable clinicians and researchers to exploit the much-neglected source of original information provided by informant-reports.

[Borderline personality disorder: state of knowledge and attitudes among french-speaking mental health professionnals]. / Trouble de la personnalité borderline: état des connaissances et des représentations auprès de praticiens francophones en santé mentale.

OBJECTIVES: Patients suffering from borderline personality disorder are very prevalent in various settings (emergency rooms, psychiatric and general hospitals, ambulatory consultations). However, it remains one of the most stigmatized and neglected mental health conditions, albeit being an area that is responsible for very interesting advances in psychotherapy. Today, the prognosis of patients with borderline personality disorder is rather favorable, provided that they follow a dedicated psychotherapy. Conceptions about this condition therefore deserve to be updated as it is sufficiently described in the literature that negative attitudes towards these patients diminish the quality of care they receive as well as their prognosis, and that these attitudes change with training. We decided to study the state of knowledge and attitudes towards borderline personality disorder in a group of French-speaking caregivers interested in these patients. METHODS: Between 2019 and 2020, at the start of training sessions in psychotherapeutic approaches to borderline personality disorder, we provided two questionnaires to 126 caregivers from various professional backgrounds (psychiatrists or child psychiatrists, psychologists, mental health nurses, social workers). The first consisted of 13 questions with 3 choice answers aimed at testing knowledge about borderline personality disorder and the second of 11 questions in the form of a Likert scale aimed at evaluating attitudes towards these patients (e.g. degree of comfort, involvement, hope, avoidance with these patients) adapted frome a questionnaire of Blake and colleagues. RESULTS: The sample consisted of 126 caregivers (69 psychiatrists/pedopsychiatrists; 19 mental health nurses; 23 psychologists; 14 social workers). Fifty three of them (42.06 %) worked in an outpatient setting (either in a state facility or in private practice), 50 (39.68 %) worked in an inpatient psychiatric unit, 13 (10.32%) in both care systems, and 10 (7.94 %) worked in other facilities such as sheltered homes or workshops for persons with psychiatric disabilities. The average number of years in postgraduate training was 7.73 (SD=5.67; rank=0 to 31), and 35 (27.78%) had received at least one training course on borderline disorder in the past. The mean age of the sample was 37.89 (SD=10.08; rank=20 to 64) and there were 76 women (60.32%) and 50 men (39.68%). Concerning the first questionnaire (knowledge), the rate of correct responses among caregivers was relatively low (54%) considering that the vast majority of those assessed were caregivers already trained in mental health who were working with patients suffering from borderline personality disorder. The results showed a significant knowledge gap among professionals, in particular in the nursing profession, illustrating an ever more flagrant shortfall in formations in this sub-population. Concerning the second questionnaire (attitudes), the answers showed that attitudes of caregivers towards patients with borderline personality disorder were still tinged with fear and lack of confidence in taking charge of them. Thus, one participant out of five would have liked to avoid these patients, more than 12% of caregivers did not appreciate them, and 23% thought that they were manipulative. In addition, nearly half of the caregivers surveyed had low confidence in their ability to make a positive difference in the lives of borderline patients. However, there was a recognition of their distress as well as a demand for dedicated training. CONCLUSIONS: Stigmas and ignorance persist around patients with borderline personality disorder. Current training courses do not allow caregivers who are on the front lines (in particular nurses) and who wish to be trained to acquire sufficient knowledge and tools necessary for the care of patients suffering from this disorder. This calls for an improvement in training as well as a reflection on the most appropriate approaches possible to the various target audiences.

Evaluation of the level of training of French psychiatrists on borderline personality disorder: An online survey.

BACKGROUND: Borderline personality disorder is a common and treatable personality disorder that is often underdiagnosed and untreated, mainly due to a lack of training of psychiatrists and to a lack of accessibility to specialized therapies. However, no study has been conducted in France regarding this issue. Thus, we aimed to evaluate on a national scale the level of training, knowledge, and general attitude toward BPD diagnosis of French psychiatrists. METHODS: We conducted an online survey in an unselected population of residents and senior French psychiatrists between January and March 2022, the results of which are presented descriptively. RESULTS: 228 psychiatrists fully answered the questionnaire, and 21 more psychiatrists answered it partially. We found that most of the responders were unsatisfied with the residency training or the continuing medical education offered regarding BPD, a lack of training resulting in a low level of self-confidence regarding BPD management, in a low number of evidence-based therapies trained psychiatrists in issues regarding diagnostic disclosure, and in misconceptions regarding some aspects of the disorder. CONCLUSIONS: These results underlie a clear lack of training of French psychiatrists, as well as a request from the latter for more opportunities to learn. This calls for a rethinking of the teaching system to incorporate more knowledge and tools related to BPD.

A comprehensive review on the role of testosterone on the neurobehavioral systems implicated in the reinforcement sensitivity theory of personality.

OBJECTIVES: The Reinforcement Sensitivity Theory (RST) is a neuropsychological theory of personality emphasizing approach and avoidance as the two core behavioral aspects. Approach is represented by the behavioral approach system (BAS). Avoidance is represented by the behavioral inhibition system (BIS) and the fight-flight-freeze system (FFFS). Although the influence of testosterone on human behavior has been demonstrated, few studies have investigated the relation between testosterone and the RST. The aim of this narrative review was to decipher the possible role of testosterone on the biological systems involved in the RST in humans. METHODS: Google scholar, PubMed, PsycARTICLES, PsycINFO, Scopus and Cochrane library databases were interrogated using keywords such as testosterone, BIS, BAS, FFFS, personality, reinforcement sensitivity theory. RESULTS: Seven original articles, published between 2009 and 2022, assessing the relation between testosterone and the systems implicated in the RST, were included. The results of these studies suggested the presence of a possible positive relation between testosterone and the BAS. However, the impact of testosterone on the BIS and/or FFFS seems to be less clear. DISCUSSION: The consistency in the results supporting the presence of a positive relation between testosterone and the BAS might lead to the consideration of testosterone as a potential correlate in the clinical assessment of several psychopathologies. The inconsistency in the conclusions regarding the impact of testosterone on the BIS and/or the FFFS might be attributed to the different questionnaires used as measurement tools. Additional research remains needed.

[Towards a pragmatic cohabitation of theoretical and clinical models: The example of "Good Psychiatric Management" in the treatment of borderline personality disorder]. / Pour une cohabitation pragmatique des modèles théoriques et cliniques : l'exemple du « Good Psychiatric Management ¼ dans le traitement du trouble de personnalité borderline.

Borderline personality disorder (BPD) is a common disorder in general and clinical populations and is related to potentially severe medical and socio-professional consequences. Treatment of BPD is based on evidence-based psychotherapies (such as Dialectical Behavioral Therapy, Mentalization-Based Therapy, Schema-Focused Therapy or Transference Focused Psychotherapy), which have been shown effective but are poorly available in France. Pharmacological treatments, which are more easily available, are not effective in treating symptoms of the disorder but can be useful in management of comorbidities. In this context, recently called "generalist" models have been developed, which every well-trained psychiatrist can implement in their daily practice, combining practical elements from evidence-based psychotherapies and elements of pharmacological management of symptoms and comorbidities. The purpose of this article is to present one of these models, the Good Psychiatric Management (GPM) and its basic principles and its applications, and to provide one of the first French-speaking resources about this model. In addition, beyond the practical elements proposed by the GPM, we discuss the deeper question that it raises, namely the question of a pragmatic integration of different theoretical and clinical models. Indeed, the treatment of BPD patients is at the junction of different conceptualizations of mental pathology (psychopathological, neurobiological) and different modalities of practice (psychotherapy, biological psychiatry). In a French context, that sometimes separates these two models, and in our opinion GPM constitutes an example of clinical collaboration which shows the interest of the combined role of psychiatrist-psychotherapist.

Does identity disturbance contribute to inhibition in borderline personality? A preliminary report.

A research protocol was developed to test a theoretical model regarding impulsivity in borderline personality (BP) disorder. It was hypothesized that the impact of identity disturbance of individuals with BP features on their response-inhibition functions could be explained by the disposition of their self-concept to increase the intensity of negative emotions. Participants with different levels of BP features were assigned to a self-description condition (N=29) that had the potential to manipulate the identity coherence, or a control condition (N=27) prior to a response inhibition task with high and low arousal emotional stimuli. We also explored the relationship between participants' self-description and their performance on the inhibition task. The results showed a significant interaction between condition, level of BP features, valence, and stimulus intensity on commission errors. Post-hoc analysis did not reveal significant differences. In addition, a moderate correlation was found between a lesser differentiated description of the self and a higher mean of errors of commission. This preliminary study highlights the relevance of studying the relationship between the self-concept and inhibition regarding borderline impulsivity. The findings should be replicated with a larger sample and with individuals who meet the diagnostic criteria.

[The alternative model of personality disorders among the French population: Assessment with brief tools]. / Le modèle alternatif des troubles de la personnalité en population française : évaluation avec des outils brefs.

OBJECTIVES: The aim of this work was to study whether the French versions of the brief tools available to clinicians within the framework of the Alternative Model of Personality Disorders (AMPD) can account for the risks of personality disorders in the general population. Tools are available to accurately investigate either the Level of Personality Functioning (LPF) or the Pathological Personality Dimensions (PPD) which in turn allow the validation of the relevance of the AMPD for its criteria A and B. As these tools, such as Morey's Level of Personality Functioning Scale Self Rated (LPFS-SR) for Criteria A or the Personality Inventory for DSM-5 (PID5) by Krueger et al. for Criteria B, are lengthy, the question arises as to the use of the short tools derived from them. METHOD: Data was collected from a sample of 433 people recruited on a volunteer basis with a complete protocol. The sample was predominantly female (83% female, 16% male, 2 people who did not wish to report their gender) and rather young (67% were 18-24 years old). The short version, the LPFS- BF of Hutsbaut et al., which we used in this work allows, as confirmed by several works, to consider on the basis of 12 items the global level of personality functioning. In order to assess the pathological dimensions of personality (PPD), we chose the short version of the Personality Inventory for DSM 5 (PID 5 BF) by Krueger et al. and used its validated French translation that satisfies the factor composition of the original version: Negative Affectivity, Antagonism, Detachment, Disinhibition and Psychoticism. To assess the intensity of personality disorders we used the dedicated subscale (Items 19 and 20) that the DSM 5 proposes in its Cross-Cutting Symptoms Measures of Level 1, in its French translation. A score higher than 2 was our Gold Standard when we tested the metric capacity of the two questionnaires to evaluate the A Criteria and then the B Criteria of the AMPD. RESULTS: The overall results (Table 1) show levels that place the group in a non-clinical level. In terms of the severity of personality disorders it can be seen that 27 % are at risk of personality disorder (PDs>2). Comparing these two sub-groups (Table 1), we observed significant differences for all the factors studied, pointing towards a higher score for people at risk of PDs. A logistic regression analysis of the evaluation of persons at risk lead us to find that gender and age do not have a significant influence (p=0.225 and p=0.065 respectively) in a valid model (chi square=157, df=4, p<0.001) including the overall score on the LPFS (z=5.76, p<0.001) and the PID 5 (z=2.26, p<0.001). The Area Under the Curve (AUC=0.859) of this translation (Table 3) is consistent with the original version (AUC=0.84). It has metrological qualities (Sn=73.91%, Sp=85.33%, LR+=5.1, LR-=0.3005) that allowed us to use a threshold of 24 as a discriminant of a risk of moderate or severe personality disorder. In addition, if we followed the AMPD and considered the threshold of 24 on the LFPS-BF to be a risk score for personality disorder, we could see (Fig. 2) that the scores on the PID 5 BF fairly well reflected the expected pattern with a large AUC (0.901). According to the AMPD, the cut-points for the dimensions that would evoke the presence of criteria B in the case of the presence of criterion A (LPFS-BF>24) could be either a score greater than 2 for Negative Affectivity, a score greater than 0.8 for Detachment, Antagonism and Disinhibition, or a score greater than 1.2 for Psychoticism (Table 4). DISCUSSION: The translation of the LPFS-BF that we used in this work has sufficient qualities to assess situations at risk of personality disorders when higher than 24. Its consistency was good (=0.84), and its factor composition in two factors (Self and Interpersonal Relations) was equivalent to the original version. The use of PID5-BF could therefore be used as a complement to the screening of AMPD A criteria, with a 25 for cut-point. The evaluation of the AMPD B criteria with the PID5-BF seemed relevant in view of our results; each of the subscales seemed to be able to correctly evaluate (AUC) persons with an LPFS-BF score at risk. However, the risk thresholds need to be confirmed in further work because of the essential role that the dimensions play in the diagnosis of types of personality disorders.

How to target disturbed identity in borderline patients? Self-identification program: A case study.

Borderline personality disorder (BPD) is a severe and relatively prevalent psychiatric disorder, responsible for high rates of suicidal behaviors. Disturbed identity appears as at the very core of this disorder, being inter-related with all other BPD features. Notably, from a dimensional perspective on mental disorders, one should realize that it is from our usual self-representation that we live all our daily experiences. Then, if the understanding of self-concept (or identity) is impaired, all the interventions implemented to decrease the self's suffering will subsequently be impaired. The purpose of the present case study was to illustrate the nine identity diffusion categories described by Jørgensen & Bøye (2022) and how the level of identity function can be improved in a third-wave cognitive and behavioral therapy targeting progressive correct self-identification.

Three clinical indicators of borderline personality disorder in anorexia nervosa: A pilot study.

OBJECTIVES: Co-occurrence of Anorexia Nervosa (AN) and borderline personality disorder (BPD) is frequent (8%-40%) and associated with specificities that impact the treatment process. Lifetime history of suicide attempt (HAS), substance use disorder (SUD) and the binge-purging subtype (B-P) might be good markers of such comorbidity. We made the hypothesis that in patients with AN, the presence of HAS, SUD and B-P have sufficient predictive power to efficiently detect an associated BPD comorbidity. METHODS: After a case report analysis on a pilot sample of 119 patients with AN, we performed a cross-sectional analysis on a confirmatory sample of 84 patients with AN in a single center specialized in eating disorders systematically assessing HAS, SUD, B-P and BPD using the Mini International Neuropsychiatric Interview for DSM-5 and the Diagnostic Interview for Borderline (DIB-R). RESULTS: B-P had a 100% negative predictive value, and the combination of SUD plus HAS had a 100% positive predictive value. On a quantitative level, B-P, HAS and SUD were independent explanatory factors of the DIB-R total score. CONCLUSIONS: The main limitations were the low number of patients, the single center analyses, the potential overlapping of assessments and the fact that data were exclusively declarative. In this study, every patient with B-P, SUD and HAS had been diagnosed with BPD.

[Is personality assessment with the French Big Five Inventory (BFI-Fr) invariant according to gender and activity of the respondents?] / La mesure de la personnalité à l'aide du Big Five Inventory français (BFI-Fr) est-elle invariante selon le genre et l'activité des répondants ?

OBJECTIVES: The BFI-Fr is an effective tool to assess the five dimensions of the five-factor model of personality. The psychometric qualities are excellent in several validation studies. However, because the inconsistency of certain items may be due to a lack of invariance between groups, we examined this invariance according to the gender and activity of the respondents. METHODS: The sample consists of 1904 participants (1232 women and 672 men; 1159 students and 745 professionals). Recruitment was done by "snowball" from different studies conducted over four years. Respondents completed the BFI-Fr. The 45 items were corrected for the acquiescence bias. The Item Response Theory methodology was used to test the invariance using the differential item functioning (DIF) test. The T scores were subject to ANCOVA and correlations to compare the differences between subgroups. RESULTS: Whatever the subsample, we found the same five-factor structure (similarities were especially high for C). The cumulative explained variances are comparable for all groups. The functioning of eight items varied between men and women; and six between activity groups, however, all but one DIF values were low. No item in domain A varied in its measure. ANCOVA results showed that women have higher A and N scores than men and that professionals have higher C and lower N scores than students. There is no interaction effect between gender and activity. When we removed the non-invariant items, the effect of gender became significant in favor of women on dimension C even if the difference remained minimal. The difference by activity on N became non-significant. There was a very strong link between activity and age and between gender and activity: in the sample, women were more often students and vice versa. CONCLUSIONS: Overall and once again, the structure and internal consistency of the Big Five as measured by the BFI-Fr was replicated in new samples. There was a differential functioning of 12 items out of 45 (about a quarter). These differences were small since only one was of moderate magnitude. The deletion of these items did not strongly change the mean comparisons between groups. Therefore, our results do not call into question the usefulness of the BFI-Fr but invite to control the extent of this differential functioning. In all cases (with or without the non-invariant items) the analyses showed significant gender differences for A and N, differences which are typically found in many studies. Students and professionals differ in their levels of C and E. Certain inconsistencies are probably due to the translation from American to French, since the BFI-Fr is based on the lexical approach (in this context, item content was somewhat dependent of languages peculiarities). Thus, the BFI-Fr allows a robust evaluation of the five dimensions but requires a prior control of the invariance of item functioning in order to ensure that the intergroup differences in E-A-C-N-O mean scores do not reflect a psychometric artifact but genuine personality differences.

[The attachment formed in addictive behaviors during the adolescent process]. / L'attachement noué dans les conduites addictives lors du processus adolescent.

At the heart of the knotting of an addiction during the adolescent process is the possibility of conceptualizing the dynamics of an addictive behavior through the prism of attachment theory. From the inheritance of a family gift, through the coloring of attachment objects, to the adolescent oedipal reactivation, the addictive behavior finds a functional echo in compensation for an inaugural lack. This lack, this deficiency from an insecure family space, conditions the appearance of a symptomatic defense embodied by the dependent attachment to external objects. The case of Mohamed illustrates these problems in the relationship to the Other while providing a clinical window on the identity issues palliated by addictive behaviors. Witha logic of having rather than being, shaped by a relationship to language oscillating between the unspeakable and the reification of his speech, Mohamed invites us, singularly, to glimpse an avenue of clinical reflection.

[Intrusive touch of borderline parenting and risk of disorganized attachment of children]. / Toucher intrusif de la parentalité borderline et risque d'attachement désorganisé des enfants.

The development of attachment in toddlers is linked to the quality of their early interactions with their mother and father. The impact of interactive dysfunctions, in relation to different parental circumstances, constitutes an important risk for the development of disorganized attachment. Although this aspect is fairly well known, few studies have been done on the children of people with borderline personality disorder.

Traduction et validation du questionnaire de dépistage Borderline Personality Questionnaire.

OBJECTIF: Disposer d'outils de dépistage valides pour évaluer le trouble de la personnalité limite est essentiel en pratique clinique et en recherche. Parmi les outils existants, le questionnaire sur la personnalité limite (BPQ) présente plusieurs qualités. Cependant, il n'existe pas de version française et il n'a pas été validé avec des adultes dans un échantillon clinique. Les objectifs de cette étude étaient : 1) traduire le BPQ en français; 2) mesurer la validité convergente, prédictive et discriminante, la cohérence interne et la fidélité test-retest. MÉTHODE: Les recommandations de Streiner, Norman et Cairney (2014) sur la traduction d'évaluations ont été suivies. Quarante adultes référés à un programme spécialisé en troubles de la personnalité ont participé à l'étude. Pour évaluer la validité du BPQ français, le questionnaire SCID-II (entrevue et auto-évaluation) fut administré et le diagnostic psychiatrique fut établi par un psychiatre à l'insu. RÉSULTATS: Aucune modification majeure n'a été apportée au BPQ français. Les analyses ont montré une cohérence interne élevée (α = 0,84), une bonne fidélité test-retest (r = 0,77), une discrimination significative avec le trouble de la personnalité schizotypique (r = -0,31; p < 0,05), une convergence significative avec le SCID-II (r = 0,72) et une validité prédictive significative du diagnostic psychiatrique (p < 0,01). CONCLUSIONS: La version française du BPQ présente des qualités psychométriques prometteuses à un usage auprès des personnes ayant un trouble de la personnalité limite.

Various mentalizing concepts in mothers with postpartum depression, comorbid anxiety, and personality disorders.

BACKGROUND: Mentalization is defined as the human capacity to reflect upon one's own or others' behaviors in terms of underlying mental states and intentions. Several concepts of mentalizing exist, which differ in content, assessment, and clinical prediction. AIMS: The present study examines the relationship between the three main concepts of mentalizing, namely, reflective functioning (RF), parental reflective functioning (PRF), and Mind-Mindedness (MM), in mothers with postpartum depression. It was hypothesized that mentalizing concepts differ in their convergent and divergent variance, as well as their clinical validity regarding comorbid anxiety and personality disorders (PDs). METHOD: Fifty clinically referred mothers with postpartum depression and infants aged 3-10 months were examined by means of the Reflective Functioning Scale, Parental Reflective Functioning Questionnaire, and Mind-Mindedness Coding-System. RESULTS: No significant associations were found between RF and PRF, or between PRF and MM; higher RF was associated with more MM-nonattuned mind-related comments. Increased depression and anxiety were linked to lower PRF in terms of higher PRF-prementalizing. Lower RF, but not PRF, was associated with comorbid PDs. Specifically, obsessive-compulsive PD was associated to considerably fewer MM-nonattuned mind-related comments. CONCLUSION: Distinct concepts of mentalizing represent divergent competencies, differentially linked to maternal postpartum psychopathology.

Trasfondo: La mentalización se define como la capacidad humana para reflexionar sobre las conductas propias y de otros en términos de estados mentales e intenciones subyacentes. Varios conceptos de mentalización existen, los cuales difieren en contenido, evaluación y predicción clínica. Propósitos: El presente estudio examina la relación entre los tres principales conceptos de mentalización, llamados Funcionamiento Reflexivo (RF), Funcionamiento Reflexivo del Progenitor (PRF), y el Estado de Conciencia de la Mente (MM) en madres con depresión postparto. La hipótesis es que los conceptos de mentalizar difieren en variantes convergentes y divergentes, así como también su validez clínica acerca de la ansiedad comórbida y trastornos de personalidad (PD). Método: Se examinaron cincuenta madres con referencia clínica por depresión de postparto e infantes con de tres a diez meses, usando la Escala de Funcionamiento Reflexivo, el Cuestionario de Funcionamiento Reflexivo del Progenitor y el Sistema de Codificación del Estado de Conciencia de la Mente. Resultados: No se encontraron significativas asociaciones entre RF y PRF, o entre PRF y MM; un más alto RF se asoció con más comentarios relacionados con la mente y un MM no en sintonía sensible. Se estableció una conexión entre el aumento en la depresión y la ansiedad con un más bajo PRF en términos de un más alto PRF de pre-mentalización. Se asoció un más bajo RF, aunque no así el PRF, con un PD comórbido. Específicamente, el PD obsesivo-compulsivo se asoció considerablemente con menos comentarios relacionados con la mente y un MM no en sintonía sensible. Conclusión: Distintos conceptos de mentalizar representan competencias divergentes, diferencialmente enlazadas a la sicopatología materna del postparto.

Contexte: La mentalisation est définie comme la capacité humaine de refléchir à ses propres comportements et les comportements des autres en terme d'états mentaux sous-jacents et les intentions. Plusieurs concepts de mentalisation existent, qui diffèrent en contenu, évaluation et la prédiction clinique. Buts: Cette étude examine la relation entre les trois concepts principaux de la mentalisation, soit le Fonctionnement Réfléchi (FR), Fonctionnement Réfléchi Parental (FRP), et l'Esprit-Qualité Mentale (en anglais mind-mindedness, abrégé ici par EQM), chez des mères avec une dépression postpartum. On a posé comme hypothèse que les concepts de mentalisation diffèrent dans leur variance convergente et divergente, ainsi que leur validité clinique concernant l'anxiété comorbide et les troubles de la personnalité (TP). Méthode: Cinquante mères cliniquement envoyées consulter avec une dépression postpartum et des nourrissons âgés de trois à 10 mois ont été examinés au moyen de l'Echelle de Fonctionnement Réfléchi, du Questionnaire de Fonctionnement Réfléchi Parental, et le Système d'Evaluation de l'Esprit-Qualité Mentale; un FR plus élevé était lié à plus de commentaires EQM. Résultats: Aucun lien important n'a été trouvé entre le FR et le FRP, ou entre le PRF et l'EQM; un FR plus élevé était lié à des commentaires EQM-nonadapté. Une dépression et de l'anxiété accentuées étaient liées à une FRP plus bas en termes de FRP-prémentalisation plus élevée. Un FR plus bas, mais pas un FRP plus bas, était lié à un TP comorbide. Plus particulièrement un TP obsessionnel compulsif était lié à beaucoup moins de commentaires EQM-nonadaptés. Conclusion: Des concepts distincts de mentalisation représentent des compétences divergentes, liées de manière différentielle à la psychopathologie maternelle postpartum.

[Hysteria: history of a concept and its clinical reality]. / L'hystérie : histoire d'un concept et de sa réalité clinique.

Hysteria is one of the oldest and best known clinical terms. Its history reveals the extent to which pathological entities, some more than others, are the fruit of successive conceptions of experts, themselves undoubtedly influenced by the prevailing currents of thought of their time. From its uterine origin to its psychogenic etiology, here is the history of hysteria and its controversies. A history that belongs to that of medicine, neurology, psychiatry, psychology and psychoanalysis.

Associations between prenatal maternal mental health indices and mother-infant relationship quality 6 to 18 months' postpartum: A systematic review.

Maternal mental disorders can significantly impact on children's psychosocial and psychological development, incurring substantial ongoing economic and personal costs. A key mediating mechanism is mother-infant relationship quality (MIRQ). Research studies and perinatal mental health screening initiatives have predominantly focused on depressive symptoms and perinatal depression as predictors of MIRQ. While maternal depression is associated with suboptimal MIRQ, the findings have not been consistent. Personality characteristics are associated with parenting and proneness to depression, presenting a potential addition to prenatal mental health assessment. We conducted a systematic review of studies that have examined the link between prenatal depressive symptoms and/or personality characteristics with postnatal MIRQ. Our findings suggest that both maternal personality traits and depressive symptoms measured in early pregnancy are associated with postnatal MIRQ. A measure of personality characteristics may enhance prenatal mental health assessment, affording opportunities for targeted intervention commencing in pregnancy to improve MIRQ, parenting, maternal mental health outcomes, and infant psychosocial and psychological development, and thereby contributing to the reduction of human and economic cost burdens.

Los trastornos mentales maternos pueden impactar significativamente el desarrollo sicosocial y sicológico de los niños lo cual conlleva considerables continuos costos económicos y personales. Un mecanismo mediador clave es la calidad de la relación madre-infante (MIRQ). Los estudios investigativos y las iniciativas de exámenes de salud mental perinatales predominantemente se enfocan en los síntomas depresivos y la depresión perinatal como factores de predicción de MIRQ. Mientras que la depresión materna se asocia con una MIRQ inferior al nivel óptimo, los resultados no son consistentes. Las características de la personalidad se asocian con la crianza y la tendencia a la depresión, lo cual presenta un posible punto adicional a la evaluación de salud mental prenatal. Llevamos a cabo una revisión sistemática de estudios que examinaron la conexión entre síntomas depresivos prenatales y/o características de la personalidad con MIRQ postnatal. Nuestros resultados sugieren que tanto las características maternas de la personalidad como los síntomas depresivos medidos durante el temprano embarazo se asocian con MIRQ postnatal. Una medición de las características de la personalidad pudiera mejorar la evaluación de salud mental prenatal lo cual permitiría oportunidades para la intervención enfocada a partir del embarazo con miras a mejorar MIRQ, la crianza, los resultados de salud mental maternos, así como el desarrollo sicosocial y sicológico del infante, contribuyendo así a reducir la carga humana y económica.

Les troubles mentaux maternels peuvent avoir un impact important sur le développement psychosocial et psychologique des enfants menant à des coûts personnels et économiques continus et importants. Un mécanisme de médiation clé est la qualité de la relation mère-nourrisson (ici abrégé en français QRMN). Les études de recherché et les initiatives de dépistage en santé mentale périnatale ont surtout porté sur les symptômes dépressifs et la dépression périnatale en tant que prédicteurs de la QRMN. Mais alors que la dépression maternelle est liée à une QRMN sous-optimale, les résultats ne sont pas uniformes et constants. Les caractéristiques de personnalité sont liées au parentage et à la propension à la dépression, présentant un ajout potentiel à l'évaluation de santé mentale prénatale. Nous avons passé en revue systématiquement toutes les études ayant examiné le lien entre les symptômes dépressifs périnataux et / ou les caractéristiques de personnalité avec une QRMN postnatale. Nos recherches suggèrent que les traits de personnalité maternelle et les symptômes dépressifs mesurés durant le début de la grossesse sont à la fois liés à la QRMN postnatale. Une mesure de caractéristiques de personnalité pourrait améliorer l'évaluation de la santé mentale prénatale et offrir des possibilités d'intervention ciblée commençant durant la grossesse, afin d'améliorer la QRMN, le parentage et les résultats de santé mentale maternelle, ainsi que le développement psychosocial et psychologique du nourrisson, contribuant donc à la réduction de la charge du coût humain et économique.

Evaluation of early relational disturbance in high-risk populations: Borderline personality disorder features, maternal mental state, and observed interaction.

Despite the longstanding theoretical association in the attachment literature between maternal trauma history and disturbances in the mother-infant interaction, few studies have investigated mechanisms of transmission of traumatogenic relational patterns in high-risk mother-infant dyads. This study investigated interrelationships among maternal trauma history, distorted maternal representations (DMRs, i.e. disturbed thoughts and feelings about the infant and self-as-parent), maternal mentalisation (i.e. capacity to conceive of self and other's intentions in terms of mental states including thoughts, feelings, and desires), and quality of interaction in a clinical sample of mothers with Borderline Personality Disorder (BPD) features and their infants (N = 61). Measures used included the Childhood Trauma Questionnaire, Parent Development Interview, Mother-Infant Relationship Scale, Borderline Symptom Checklist-23, and the Emotional Availability Scales. The results indicated BPD features mediated the relationship between maternal trauma history and DMRs predicting disturbance in interaction. In addition, analyses showed that maternal mentalisation had a buffering effect between DMRs and maternal non-hostility and yet the severity of BPD features moderated the relationship between mentalisation and DMRs. The findings suggest postpartum borderline pathology may adversely impact the experience of being a parent for women with a relational trauma history including deficits in mentalisation (i.e. hypermentalising) and disturbances in the mother-infant interaction. Implications for research and clinical practice are discussed.

A pesar de la larga asociación teorética en la literatura de la afectividad entre el historial de trauma materno y perturbaciones en la interacción madre-infante, pocos estudios han investigado mecanismos de transmisión de patrones de relación traumatogénicos en díadas madre-infante de alto riesgo. Este estudio investigó interrelaciones entre el historial de trauma materno, las distorsionadas representaciones maternas (DMR, v.g. pensamientos y sentimientos perturbados acerca del infante y de sí misma como madre), la mentalización materna (v.g. capacidad para concebir las intenciones propias y de otros en términos de estados mentales), y la calidad de interacción en un grupo muestra clínico de madres con características de Trastornos de Personalidad Limítrofe (BPD) y sus infantes (N = 61). Entre las medidas usadas están el Cuestionario de Trauma de Niñez, la Entrevista de Desarrollo de la Progenitora, la Escala de Relación Madre-Infante, la Lista de Verificación de Síntomas de Personalidad Limítrofe - 23, y las Escalas de Disponibilidad Emocional. Los resultados indicaron que las características BPD mediaron la relación entre el historial de trauma materno y las DMR prediciendo perturbaciones en la interacción. Es más, los análisis mostraron que la mentalización materna tenía un efecto amortiguador entre las DMR y la no hostilidad materna y aun así la severidad de las características BPD moderaron la relación entre la mentalización y las DMR. Los resultados sugieren que la patología limítrofe posterior al parto pudiera impactar adversamente la experiencia de ser madre para mujeres con historial de trauma, incluyendo déficits en la mentalización (v.g. la hipermentalización) y las perturbaciones en la interacción madre-infante. Se discuten las implicaciones para la investigación y la práctica clínica.

En dépit de la longue association théorique dans les recherches sur l'attachement entre le passé de trauma de la mère et les perturbations dans l'interaction mère-bébé, il existe peu d'études portant sur les mécanismes de transmission de patterns relationnels traumagénétiques chez les dyades mère-bébé à haut risque. Cette étude s'est penchée sur les interrelations entre le passé de trauma de la mère, des représentations maternelles déformées (des DMR, c'est-à-dire des pensées déformées ainsi que des sentiments déformés sur le bébé et soi-même en tant que parent), la mentalisation maternelle (c'est-à-dire la capacité de concevoir ses propres intentions ainsi que celles des autres en termes d'états mentaux), et la qualité de l'interaction chez un échantillon clinique de mères ayant les caractéristiques du trouble de la personnalité limite et leurs bébé (N = 61). Les mesures utilisées ont inclus le Questionnaire de Trauma de l'Enfance, l'Entretien du Développement du Parent, l'Echelle de Relation Mère-Bébé, la Checklist de Symptômes de la Personnalité Limite-23, ainsi que les Echelles de Disponibilité Emotionnelle. Les résultats ont indiqué que les traits de TPL affectaient la relation entre l'histoire de trauma de la mère et les DMS = R prédisant une perturbation dans l'interaction. De plus les analyses ont montré que la mentalisation maternelle faisait effet de tampon entre les DMR et la non-hostilité maternelle et pourtant la sévérité des traits TPL modérait la relation entre la mentalisation et les DMR. Les résultats suggèrent qu'une pathologie limite postpartum pourrait avoir un impact adverse sur l'expérience de parentage pour les femmes ayant un passé de trauma, y compris des déficits dans la mentalisation (par exemple, une hyper-mentalisation) et des perturbations dans l'interaction mère-bébé. Les implications pour les recherches et la pratique clinique sont discutées.