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1.
Semin Diagn Pathol ; 37(4): 179-186, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32448592

RESUMO

Neurogenic tumors represent a broad ill-defined category of neoplasms that includes tumors of Schwann cell and/or neuroblastic derivation, as well as neoplasms that typically develop in the central nervous system, but rarely present in ectopic sites including the mediastinum. Neurogenic tumors may occur at many different anatomic sites, but the mediastinum represents a uniquely challenging site given the complex anatomy. Additionally, some of these neoplasms may present with multicentric involvement in the context of genetic syndromes, including NF1, NF2 and schwanomatosis. Most of these develop in posterior structures, often in association with paraspinal structures. Fine needle biopsy/small biopsies play an important role in the diagnosis of these neoplasms, given its record of safety and the increased applicability of ancillary testing to these smaller samples at the present time. In this review we focus on the major categories of neurogenic tumors that may be encountered in the mediastinum, including schwannoma, neurofibroma, malignant peripheral nerve sheath tumors, ganglioneuroma and ganglioneuroblastoma, as well as rarer members of this category. We discuss diagnostic approaches applicable to small cytologic and tissue samples and relevant differential diagnoses.


Assuntos
Neoplasias do Mediastino/diagnóstico , Neoplasias do Mediastino/patologia , Neoplasias de Tecido Nervoso/diagnóstico , Neoplasias de Tecido Nervoso/patologia , Humanos
2.
Ann Chir Plast Esthet ; 58(4): 336-41, 2013 Aug.
Artigo em Francês | MEDLINE | ID: mdl-23582620

RESUMO

The persistent sciatic artery is a rare cause of painful buttock mass with L5-S1 radicular signs. A 56-year-old man presents a right painful buttock mass with L5-S1 radicular symptoms for 3 years. The surgical exploration found a pulsatile vascular mass like a persistent sciatic artery aneurysm. This vascular pathology is a misunderstood embryogenesis anomaly. The treatment aims to avoid serious complications. This pathology must be known from plastic surgeon.


Assuntos
Aneurisma/diagnóstico , Aneurisma/cirurgia , Nádegas/irrigação sanguínea , Dor Crônica/etiologia , Artéria Ilíaca/anormalidades , Radiculopatia/etiologia , Nervo Isquiático/irrigação sanguínea , Implante de Prótese Vascular , Diagnóstico Diferencial , Artéria Femoral/anormalidades , Artéria Femoral/patologia , Humanos , Artéria Ilíaca/patologia , Angiografia por Ressonância Magnética , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade
3.
Cureus ; 13(1): e12584, 2021 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-33457146

RESUMO

Facial nerve tumors constitute about 5% of all facial nerve paralysis. As it is relatively uncommon, it could be misdiagnosed. We encountered an 18-year-old girl who had right facial weakness since the age of four, referred to otorhinolaryngology clinic for further evaluation only when her hearing deteriorated and the facial weakness worsened. Further investigation revealed facial nerve schwannoma. Facial nerve paralysis in the pediatric age group is uncommon and should be examined in detail to rule out other possible etiologies besides Bell's palsy.

4.
Artigo em Inglês | MEDLINE | ID: mdl-34535223

RESUMO

BACKGROUND AND OBJECTIVE: Vestibular schwannoma is a benign tumour that originates in the eighth cranial nerve. It is termed intralabyrinthine schwannoma (ILS) when it develops in the inner ear, this being a rare origin. We present our experience in the management of three patients with ILS. MATERIALS AND METHODS: The results of tumour excision and cochlear implantation were evaluated in three patients with ILS: two intracochlear schwannomas (ICS) and one intravestibular schwannoma (IVS). RESULTS: Prior to surgery, all patients presented progressive sensorineural hearing loss and tinnitus. Complete tumour resection and cochlear implantation was possible in all patients, with favourable hearing rehabilitation. CONCLUSIONS: The therapeutic approach will depend on tumour size, growth rate, degree of hearing loss and presence of vestibular symptoms. Cochlear implantation (CI) in patients with ILS is possible when the cochlear nerve is present and functional. CI in patients, whether or not preceded by tumour excision, is an option with good hearing results in selected patients.


Assuntos
Implante Coclear , Implantes Cocleares , Neurilemoma , Vestíbulo do Labirinto , Nervo Coclear , Humanos , Neurilemoma/cirurgia
5.
Neurocirugia (Astur : Engl Ed) ; 32(6): 268-277, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34743824

RESUMO

INTRODUCTION AND OBJECTIVES: To determine the safety and efficacy of endoscopic keyhole surgery in patients with cerebellopontine angle tumours. MATERIALS AND METHODS: This was a retrospective study of patients with cerebellopontine angled tumours treated by fully endoscopic retrosigmoid keyhole approach in a tertiary centre during a period of four years. Preoperative, transoperative and postoperative variables were analysed. RESULTS: A number of 40 patients were included. The age average was 49.4 years and male/female proportion was 0.4-1. We found 31 vestibular schwannomas (77.5%), five meningiomas (12.5%), two cholesteatomas (5.0%) and two metastases (5.0%). Vestibular schwannomas Hannover type IIIb, IVa and IVb predominated. The surgical resection was total or near-total 92.5% of patients. Hearing preservation rate was 62.5% and acceptable facial function nerve function rate was 80% after six months. Hospital stay was 7.5 days. The total or near total resection and functionally preservation rate was high. Complications were unusual. CONCLUSIONS: Endoscopic retrosigmoid keyhole approach represented a safe and efficient procedure in selected patients with cerebellopontine angle tumours.


Assuntos
Neoplasias Meníngeas , Neuroma Acústico , Craniotomia , Endoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neuroma Acústico/cirurgia , Estudos Retrospectivos
6.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33375997

RESUMO

INTRODUCTION AND OBJECTIVES: To determine the safety and efficacy of endoscopic keyhole surgery in patients with cerebellopontine angle tumors. MATERIALS AND METHODS: This was a retrospective study of patients with cerebellopontine angled tumors treated by fully endoscopic retrosigmoid keyhole approach in a tertiary center during a period of four years. Preoperative, transoperative and postoperative variables were analyzed. RESULTS: A number of 40 patients were included. The age average was 49.4 years and male/female proportion was 0.4-1. We found 31 vestibular schwannomas (77.5%), five meningiomas (12,5%), two cholesteatomas (5,0%) and two metastases (5.0%). Vestibular schwannomas Hannover type IIIb, IVa and IVb predominated. The surgical resection was total or near-total 92.5% of patients. Hearing preservation rate was 62.5% and acceptable facial function nerve function rate was 80% after six months. Hospital stay was 7.5 days. The total or near total resection and functionally preservation rate was high. Complications were unusual. CONCLUSIONS: Endoscopic retrosigmoid keyhole approach represented a safe and efficient procedure in selected patients with cerebellopontine angle tumors.

7.
Int. j interdiscip. dent. (Print) ; 16(1): 79-81, abr. 2023. ilus
Artigo em Espanhol | LILACS | ID: biblio-1440281

RESUMO

El schwanoma es un tumor neural que se origina en las células de Schwann presentes en la vaina nerviosa cuya localización más frecuente a nivel oral es el dorso de lengua, siendo mucho más frecuente en adultos. En población pediátrica la presentación es muy rara siendo lengua su ubicación más frecuente, mientras que a nivel palatino solo se conocen 11 reportes en menores de 16 años. El objetivo de este reporte es presentar un caso clínico inusual de schwanoma palatino en un niño chileno de 12 años de edad, quien fue derivado con diagnóstico clínico presuntivo de carcinoma mucoepidermoide. El caso se complementó con radiografía panorámica, Conebeam, y luego biopsia incisional. Finalmente, se diagnosticó schwanoma palatino variedad sólida. Es importante considerar al schwanoma como diagnóstico diferencial en casos de tumores palatinos, en especial en casos pediátricos ya que se pueden presentar similares características clínicas a tumores de glándula salival.


The Schwannoma or neurilemmoma tumor originates from Schwann cells present in nerve sheaths. At oral level, its most frequent location is at the back of the tongue, being much more frequent in adults. In the pediatric population, this occurrence is rare and most frequently found in the tongue. At palatal level, only 11 reports are known in children under 16 years of age. The aim of this report is to present an unusual clinical case of palatal schwannoma in a 12-year-old Chilean boy, referred with a clinical diagnosis of mucoepidermoid carcinoma. The case was complemented with panoramic radiography and Cone beam, for its subsequent incisional biopsy. Finally, a solid palatal schwannoma was diagnosed. It is important to consider schwannoma as a differential diagnosis in cases of palatal tumors, especially in pediatric cases, since they can present similar clinical characteristics to salivary gland tumors.


Assuntos
Humanos , Masculino , Criança , Células de Schwann , Neoplasias Bucais , Neurilemoma
8.
Rev. cuba. med. mil ; 52(4)dic. 2023. ilus, tab
Artigo em Inglês | LILACS-Express | LILACS, CUMED | ID: biblio-1559871

RESUMO

Introduction: Treatment options for hydrocephalus related to posterior fossa tumors have been extensively studied in the pediatric population, but the value of endoscopic third ventriculostomy in hydrocephalus secondary to vestibular schwannoma in adults, is controversial. A systematic search of the medical literature was carried out in Pubmed/Medline and SciElo for the identification and inclusion of articles, in addition to the preprint servers bioRxiv and medRxiv. The following descriptors were used: hydrocephalus and vestibular schwannomas or acoustic neuromas or acoustic neurinomas and endoscopic third ventriculostomy. The initial search found 195 articles. After selection, 5 articles were chosen for the study. Objective: To specify the role of the endoscopic third ventriculostomy in hydrocephalus secondary to vestibular schwannomas. Development: The articles included a total of 82 patients, in which an improvement of the symptoms was achieved in 86.6 percent of the cases. The decrease in ventricular diameter was reported in 82.9 percent of the cases and was only found explicit in 3 articles. Although the failure criteria used were varied, 2 of them predominated: the persistence of progressive symptomatic hydrocephalus and/or the need for shunt placement. Endoscopic third ventriculostomy failure only represented 14.6 percent. Conclusions: Third ventriculostomy is an acceptable technique with relative success for the treatment of symptomatic obstructive hydrocephalus secondary to vestibular schwannomas(AU)


Introducción: Las opciones de tratamiento para la hidrocefalia relacionada con tumores de fosa posterior han sido ampliamente estudiadas en la población pediátrica, pero es controvertido el valor de la tercer ventriculostomía endoscópica, en la hidrocefalia secundaria a schwanoma vestibular en adultos, previo a la resección del tumor. Se realizó una búsqueda sistemática de la literatura médica en Pubmed/Medline y SciElo para la identificación e inclusión de artículos, además de los servidores de preprint bioRxiv y medRxiv. Se utilizaron los siguientes descriptores: hydrocephalus y vestibular schwannomas o acoustic neuromas o acoustic neurinomas y endoscopic third ventriculostomy. La búsqueda inicial encontró 195 artículos. Después de la selección, se eligieron 5 artículos para el estudio. Objetivo: Especificar el papel de la tercer ventriculostomía endoscópica en la hidrocefalia secundaria a schwanomas vestibulares. Desarrollo: Los artículos incluyeron un total de 82 pacientes, en los que se logró una mejoría de los síntomas en el 86,6 por ciento de los casos. La disminución del diámetro ventricular se reportó en el 82,9 por ciento de los casos y solo se encontró explícita en 3 artículos. Aunque los criterios de fracaso utilizados fueron variados, predominaron dos de ellos: la persistencia de hidrocefalia sintomática progresiva o la necesidad de colocación de derivación. La falla de la tercer ventriculostomía endoscópica solo representó el 14,6 por ciento. Conclusiones: La tercera ventriculostomía endoscópica es una técnica aceptable y con relativo éxito para el tratamiento de la hidrocefalia obstructiva sintomática secundaria a schwanomas vestibulares(AU)


Assuntos
Humanos
9.
Rev. cuba. cir ; 62(3)sept. 2023.
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1550831

RESUMO

Introducción: Los schwanomas vestibulares son lesiones clasificadas como grado I por la Organización Mundial de la Salud. Las opciones conductuales incluyen la observación, la radiocirugía o la resección microquirúrgica endoscópica. Objetivo: Describir el rol del tratamiento multimodal en los schwanomas vestibulares. Métodos: Se realizó una búsqueda sistemática de literatura médica para la identificación e inclusión de artículos en las siguientes bases de datos: PubMed/Medline, SciELO y Google Scholar, además de los servidores de preprints BioRvix y MedRvix. Se usaron los siguientes descriptores: vestibular schwanoma OR acoustic neuroma AND nerve centered approach OR combined approach AND partial resection OR subtotal resection OR near total resection. Se excluyeron editoriales, cartas al editor, libros, revisiones, metaanálisis y aquellos artículos con método deficiente de más de 20 años de publicación o sin mención al tema de interés. Fueron incluidos 16 artículos. Desarrollo: Los artículos incluyeron un total de 699 pacientes, de los cuales solo 228 (32,6 porciento) recibieron radioterapia en el período posoperatorio. El período de seguimiento promedió 49,6 meses. La preservación de la función facial se logró en el 88,3 porciento de los casos y el control tumoral en el 80,7 porciento. El estado de la preservación auditiva solo fue informado en el 50 porciento de los estudios. El uso de la radioterapia adyuvante mostró gran variabilidad. Conclusiones: El tratamiento multimodal para los schwanomas vestibulares grandes -compuesto por la resección subtotal, vaciamiento intratumoral, seguido de radiocirugía- se ha convertido en una opción plausible. Se necesita la publicación de mayor cantidad de reportes para ofrecer recomendaciones y estratificar la conducta(AU)


Introduction: Vestibular schwannomas are lesions classified as grade I by the World Health Organization. Behavioral options include observation, radiosurgery or endoscopic microsurgical resection. Objective: To describe the role of multimodal treatment for vestibular schwannomas. Methods: A systematic search of medical literature, for the identification and inclusion of articles, was carried out in the databases PubMed/Medline, SciELO and Google Scholar, as well as in the preprint servers BioRvix and MedRvix. The following descriptors were used: vestibular schwannoma OR acoustic neuroma AND nerve centered approach OR combined approach AND partial resection OR subtotal resection OR near total resection. Editorials, letters to the editor, books, reviews and metaanalyses were excluded, as well as articles with deficient method of more than 20 years of publication or not mentioning the topic of interest. Sixteen articles were included. Development: The articles included a total of 699 patients, of which only 228 (32.6 ) received radiotherapy in the postoperative period. The average follow-up period was 49.6 months. Preservation of facial function was achieved in 88.3 percent of cases; and tumor control, in 80.7 percent. Hearing preservation status was reported in only 50 percent of the studies. The usage of adjuvant radiotherapy showed great variability. Conclusions: Multimodal treatment for large vestibular schwannomas -composed of subtotal resection and intratumoral draining, followed by radiosurgery- has become a plausible option. The publication of a greater amount of reports is necessary to provide recommendations and stratify the behavior(AU)


Assuntos
Humanos , Neuroma Acústico/diagnóstico por imagem , Literatura de Revisão como Assunto , Bases de Dados Bibliográficas
10.
Artigo em Inglês, Português | LILACS | ID: biblio-1369475

RESUMO

Introdução: O schwanoma é um tumor pouco frequente que se origina das células de Schwann que recobrem os prolongamentos nervosos. A malignidade desses tumores é ainda mais rara, correspondendo a 5-10% de todos os sarcomas. O prognóstico é reservado, mesmo após completa ressecção cirúrgica. Relato do caso: Paciente do sexo masculino, 79 anos, apresentou-se com lesão crostosa em perna esquerda com dois meses de evolução. A biópsia da lesão inicialmente revelou sarcoma pleomórfico, mas seu padrão imuno-histoquímico confirmou tumor maligno da bainha do nervo periférico. O tumor desenvolveu metástase linfonodal, pulmonar e adrenal dentro de poucos anos após o diagnóstico inicial. A ressecção do tumor adrenal não foi possível. O paciente desenvolveu síndrome paraneoplásica e teve piora do estado clínico, evoluindo a óbito. Conclusão: Tendo em vista a forma inespecífica do aparecimento do tumor e sua agressividade, é importante ressaltar o papel da ressecção cirúrgica ampla no seu tratamento. Além disso, fica evidente a necessidade de novos relatos desse tipo de neoplasia para melhor definição de uma conduta mais apropriada, principalmente em casos de recorrência ou disseminação metastática


Introduction: Schwannoma is a rare type of tumor which grows from Schwann cells, that protect nerve extensions. The malignancy of these tumors is even rarer, corresponding to 5-10% of all sarcomas. The prognosis is dismal, even after complete surgical resection. Case report: A 79-year-old male patient presented with a crusted lesion in his left leg with two months of evolution. Initially, the biopsy of the lesion revealed pleomorphic sarcoma, but its immunohistochemical pattern was peripheral nerve sheath malignant tumor. The tumor developed lymph node, lung, and adrenal metastasis within a few years after the first diagnosis. Adrenal tumor resection was not possible. The patient developed paraneoplastic syndrome and his clinical status worsened, progressing to death. Conclusion: In view of the nonspecific form of tumor appearance and its aggressiveness, it is important to highlight the role of wide surgical resection in its treatment. In addition, it is clear that new case reports of this type of neoplasia are necessary for better definition of more appropriate conducts, especially in recurrence or metastatic cases


Introducción: El schwannoma es un poco común, el cual se origina en las células de Schwann, que cubren las extensiones nerviosas. La malignidad de estos tumores es aún más rara, y representa 5-10% de todos los sarcomas. El pronóstico es reservado, incluso después de una resección quirúrgica completa. Relato del caso: Varón de 79 años que presenta una lesión costrosa en la pierna izquierda a los dos meses de evolución. La biopsia de la lesión reveló inicialmente un sarcoma pleomórfico, pero su patrón inmunohistoquímico era un tumor maligno de la vaina del nervio periférico. El tumor desarrolló metástasis en los ganglios linfáticos, pulmones y suprarrenales pocos años después del diagnóstico. La resección del tumor suprarrenal no fue posible. El paciente desarrolló síndrome paraneoplásico y empeoró el estado clínico, progresando hasta la muerte. Conclusión: Dada la forma inespecífica de aparición del tumor y su agresividad, es importante destacar el papel de la resección quirúrgica amplia en su tratamiento. Además, existe una clara necesidad de nuevos informes de este tipo de neoplasias para definir mejor un abordaje más adecuado, especialmente en casos de recurrencia o diseminación metastásica


Assuntos
Humanos , Masculino , Idoso , Neoplasias do Sistema Nervoso Periférico , Neurofibrossarcoma , Glândulas Suprarrenais , Pulmão , Metástase Neoplásica , Neurilemoma
11.
Clin Pract ; 6(4): 849, 2016 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-28028429

RESUMO

Schwannomas are generally benign, slow growing tumors. They are rarely observed in the gastrointestinal tract with the most common site being the stomach. These tumors are usually asymptomatic. The preoperative diagnosis via endoscopy is a challenging issue due to the difficulty of differentiation from other submucosal tumors. A 54-year-old woman presented with epigastric pain persisting for the last 10 months. Upper endoscopy revealed an elevated submucosal mass of the gastric antrum. The overlying mucosa was normal. Biopsy specimens yielded only unspecific signs of mild inactive chronic inflammation. Endoscopic ultrasound examination noted a hypoechoic homogeneous mass lesion located in the gastric antrum. The mass appeared to arise from the muscularis propria, and there was no perigastric lymphadenopathy. A contrast-enhanced computed tomography scan identified a homogeneous round mass and arising from the antrum of the stomach. Submucosal tumor was suspected and surgical intervention was recommended. The patient underwent an elective laparoscopic partial gastrectomy. The histopathologic features and immunohistochemical-staining pattern were consistent with a benign gastric schwannoma. Our patient shows no recurrence with a follow-up of one year. The definitive diagnosis of gastric schwannomas requires immunohistochemical studies. Complete margin negative surgical resection, as in this case, is the curative treatment of choice. The clinical course is generally benign.

12.
Oral Oncol ; 50(5): 421-30, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24589290

RESUMO

Parapharyngeal space tumours are rare and most clinicians will only see a small number during their career. We performed a systematic review of 1143 parapharyngeal space tumors published in the past 20 years to increase cumulative experience. A systematic literature review was performed and data on histological diagnosis, presentation, surgical approach and postoperative complications of cases published between 1989 and 2009 were compiled and reviewed. The systematic review identified a total of 1143 parapharyngeal space tumors presented in 17 studies. A majority (82%) were benign and 18% were malignant. The most common presentation was a cervical mass (50%) or an intraoral mass (47%). Approximately 70 different histologic subtypes of parapharyngeal space tumors were reported in the cumulative series. The most common primary lesion was a pleomorphic adenoma (34%). Ninety-five percent of patients underwent surgery. The most frequent approach and used to excise the lesions was the cervical approach (48%) and the commonest complication was the vagus nerve injury seen in 14% of the cases.


Assuntos
Neoplasias Faríngeas/patologia , Humanos
13.
Rev. Odontol. Araçatuba (Impr.) ; 39(2): 13-16, maio/ago. 2018. ilus
Artigo em Português | LILACS, BBO | ID: biblio-913458

RESUMO

Introdução: O schwannoma é uma neoplasia benigna que se origina nas células de Schwann da bainha de mielina dos nervos periféricos motores, sensitivos, simpáticos e dos pares cranianos. Apresenta etiologia desconhecida, e raramente ocorre em região buco-maxilo-facial (aproximadamente 1% dos casos), necessitando de tratamento cirúrgico da lesão. Objetivo: Relatar o caso de uma paciente com schwannoma benigno em cavidade oral, com tratamento cirúrgico para remoção da lesão. Relato de Caso: Paciente do gênero feminino, 18 anos, compareceu ao ambulatório do Serviço de Cirurgia e Traumatologia Buco-Maxilo-Facial da Universidade Federal da Bahia com a seguinte queixa principal: "tem uma lesão na minha boca". Ao exame clínico foi possível observar aumento de volume de consistência firme, séssil, limites bem definidos, de coloração semelhante à mucosa, em região de palato duro. Após biópsia incisional, o laudo concluiu compatibilidade com schwannoma benigno. O plano de tratamento incluiu a abordagem cirúrgica da lesão e posterior análise histopatológica, confirmando o diagnóstico de schwannoma benigno. Considerações finais: A excisão cirúrgica do schwannoma benigno com margem de segurança favorece um bom prognóstico para o paciente, bem como menor chance de recidivas e de transformação maligna da lesão(AU)


Introduction: Schwannoma is a benign neoplasm that originates in the Schwann cells of the myelin sheath of peripheral motor, sensory, sympathetic nerves and cranial nerves. It presents unknown etiology, and rarely occurs in the maxillofacial region (approximately 1% of cases), requiring surgical treatment of the lesion. Objective: To report the case of a patient with benign schwannoma in the oral cavity, with surgical treatment to remove the lesion. Case Report: Patient V.M.S., female, 18 years old, attended the clinic of the Department of Oral and Maxillofacial Surgery and Traumatology of the Federal University of Bahia with the following main complaint: "there is a lesion in my mouth". At the clinical examination, it was possible to observe an increase in the volume of firm consistency, sessile, well-defined limits of mucosa-like staining in the hard palate region. Absence of painful complaints on palpation. After an incisional biopsy, the report concluded compatibility with benign schwannoma. The treatment plan included the surgical approach of the lesion under general anesthesia. The lesion was excised (with a safety margin) and histopathological analysis was performed, confirming the diagnosis of benign schwannoma. Final considerations: Surgical excision of the benign schwannoma with margin of safety favors a good prognosis for the patient, as well as a lower chance of relapse and malignant transformation of the lesion(AU)


Assuntos
Humanos , Feminino , Adolescente , Neoplasias Bucais , Neurilemoma , Patologia Bucal , Cirurgia Bucal
14.
Rev. bras. neurol ; 52(3): 29-33, jul.-set. 2016. ilus
Artigo em Português | LILACS | ID: biblio-2614

RESUMO

O schwanoma vestibular é uma neoplasia que se origina das células de Schwann da porção vestibular do VIII nervo craniano e que corres- ponde a cerca de 10% dos tumores intracranianos e a 80% a 90% daqueles localizados no ângulo pontocerebelar. Apesar do crescimento lento e evolução em geral benigna, estes tumores podem evoluir de maneira desfavorável devido à localização em compartimento anatômico relativamente reduzido no crânio (fossa posterior), o que pode levar a compressão de estruturas nobres (como o tronco encefálico) e a desenvolvimento de hidrocefalia obstrutiva, especialmente nos raros casos de schawanomas gigantes (> 40 mm). Apresentamos relato de caso de paciente com quadro de tinnitus e hipoacusia à esquerda que evoluiu de forma subaguda com alterações do humor, da cognição e da marcha cujo diagnóstico final foi de schwanoma gigante do VIII nervo craniano.


Vestibular schwannoma is a Schwann cells neoplasia of the vestibular branch of the VIII cranial nerve and it accounts for 10% of intracranial tumours and to 80%-90% of those located at the cerebellopontine angle. Despite slow growth and usual benign evolution, unfavourable outcomes may occur, especially in the rare cases of giant schwanno- mas (> 40mm). Owing the fact that this tumours are located in a relatively narrow space (posterior fossa), giant schwannomas may compress noble areas (as the brainstem), which can also cause obstructive hydrocephalus. We discuss a case report of a 48 years old woman complaining of left-sided hearing loss and tinnitus that developed a subacute cognitive impairment, mood disorder and gait disturbance, diagnosed with giant schwannoma of the VIII nerve.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Neuroma Acústico/cirurgia , Neuroma Acústico/complicações , Neuroma Acústico/diagnóstico , Neoplasias dos Nervos Cranianos/diagnóstico , Imageamento por Ressonância Magnética/métodos , Transtornos Cognitivos/etiologia , Progressão da Doença , Transtornos do Humor/etiologia , Perda Auditiva/etiologia
15.
J Maxillofac Oral Surg ; 9(2): 182-5, 2010 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22190783

RESUMO

The tumours of the parapharyngeal region account for only 0.5% of all the head and neck tumours. Interestingly schwanomas are much common in this region. Here a case of schwanoma of parapharyngeal space in a 24-year-old female is reported with an emphasis on surgical treatment.

16.
J. vasc. bras ; 12(4): 312-314, Oct-Dec/2013. graf
Artigo em Inglês | LILACS | ID: lil-699142

RESUMO

Schwannoma is a rare cause of benign tumors of the larynx. The first-choice treatment is surgical resection. The objective of this paper is to report on a rare case of a young female patient who suffered severe intraoperative hemorrhaging during surgical resection of a laryngeal Schwannoma and needed emergency embolization.


O schwanoma representa etiologia rara de tumor benigno de laringe, tendo como principal tratamento a ressecção cirúrgica. O objetivo deste trabalho é relatar um caso raro de paciente jovem submetido à ressecção cirúrgica de schwanoma laríngeo, evoluindo, no transperatório, para complicação hemorrágica grave e necessitando de embolização de urgência.


Assuntos
Humanos , Feminino , Adulto , Excisão de Linfonodo/reabilitação , Lesões das Artérias Carótidas/complicações , Neurilemoma/diagnóstico , Pescoço , Tomografia Computadorizada Quadridimensional/métodos
17.
Int. j. odontostomatol. (Print) ; 7(2): 199-201, Aug. 2013. ilus
Artigo em Espanhol | LILACS | ID: lil-690503

RESUMO

El Schwanoma corresponde a un tumor neurogénico benigno, derivado de las células de la cresta neural, específicamente de las células de la vaina periférica nerviosa llamadas schwannocitos. El 25% de éstos, se presentan en cabeza y cuello, y sólo un 1% se presentan en la cavidad oral, principalmente en la lengua. Presentamos un caso de una niña de 13 años de edad con diagnóstico de Schwannoma de lengua. El propósito de este reporte es enfatizar que el schwanoma lingual es un diagnóstico diferencial a considerar, pese a su baja prevalencia, entre todas las otras lesiones linguales en niños o adolescentes.


A schwannoma is a benign neurogenic tumour originating from schwannocyte of the nerve sheat. A 25% of all schwannomas are seen in the tissues of the head and neck and only a 1% of them are located in oral cavity, especially in tongue. We report the case of a 13 year old girl diagnosed with a schwannoma of the tongue. The purpose of this report is to empathize that schwannoma of the tongue is a differential diagnostic to consider among all other lingual lesions in children or adolescents.

18.
Rev. habanera cienc. méd ; 11(4): 505-510, sep.-dic. 2012.
Artigo em Espanhol | LILACS | ID: lil-658899

RESUMO

Introducción:el Schwanoma forma parte de los tumores que derivan de la vaina nerviosa, de crecimiento lento, asintomático en una parte de los casos, raro en la cavidad bucal y de etiología desconocida, con lo que su diagnóstico definitivo es anatomopatológico. No encontramos ningún reporte en las revistas electrónicas cubanas ni yemenitas sobre esta afección, lo cual sumado a su comportamiento no patognomónico y su rareza, nos motivó a reportar el caso. Objetivo: presentar un caso de un tumor bucal raro, con localización lingual poco frecuente. Presentación del caso: paciente masculino de 26 años de edad, procedente de Yemen, quien acude al Servicio de Cirugía Maxilofacial de la Universidad de Adén, por presentar aumento de volumen en la lengua de un año de evolución, asintomático hasta 10 días antes que se lo traumatizó y comenzó con molestias; se interpretó inicialmente como un granuloma piógeno; se decidió su escisión y biopsia para el diagnóstico definitivo, la cual se realizó bajo anestesia local sin complicaciones, con una evolución postoperatoria favorable. El resultado del examen histopatológico fue Schwanoma lingual. Discusión: se analizan los diferentes tumores benignos y malignos que en la lengua pueden confundir el diagnóstico, se valora el comportamiento no patognomónico de la entidad y a diferencia de la localización posterior reportada por muchos autores, la punta lingual fue la afectada en nuestro caso. Conclusiones: el Schwanoma es una rara afección de la cavidad bucal, que requiere el análisis histopatológico para su diagnóstico definitivo y con un buen pronóstico postquirúrgico.


Introduction: schwannoma is one of the tumors derivates from neural sheet, characterized by a slow growing, symptomless in some cases, rare in the oral cavity, unknown etiology which definitive diagnosis should be made by the anatomopathologic analysis. Not any reports at the Cubans or Yemenis electronic journals were founded. This observation in conjunction with the not patognomonic way of presentation and rareness of the lingual Schwannoma, motivated us to report this case. Objective: to present a case of rare oral tumor, with uncommon tongue location. Case presentation: a 26 years old male patient, from Yemen was attended at the Maxillofacial Service of Aden University, complaining about a mass on the tongue since one year ago which was asymptomatic, but about ten days ago the patient suffered from a masticatory trauma that produced some discomfort. Initial diagnosis was as pyogenic granuloma; excision and biopsy were made under local anesthesia to achieve the final diagnosis. Not any complications and a favorable postsurgical evolution were observed. The conclusion of the histopathological study was lingual Schwannoma. Discussion: different benign and malignant tumors of the tongue that make confusion in the diagnosis of this disease were analyzed and the not patognomonic behavior of this affection was taking into account. Many authors report about the posterior localization of this tumor, but in our case was localized at the tip of the tongue. Conclusions: Schwannoma is a rare disease of the oral cavity that requires histopathological analysis for the final diagnosis and has a good postsurgical prognosis.

19.
Artigo em Espanhol | LILACS | ID: lil-598145

RESUMO

Se reporta el caso de un schwanoma del nervio facial que compromete el nervio desde la porción laberíntica hasta la intraparotídea, con erosión de la cápsula ótica a nivel de la cóclea y función facial normal. Mediante decompresión nerviosa se logró preservación de las funciones facial y auditiva y a los 20 meses posoperatorios no hay evidencia de crecimiento tumoral. Se discuten las diferentes alternativas terapéuticas para aquellos casos con función facial y coclear normales.


This report describes a patient with a large facial nerve schwannoma, which involves the facial nerve from its labyrinthine portion until its intra parotid portion with normal facial function. There was also a mild erosion of the otic capsule. It was treated with nerve decompression with facial function andhearing preservation after two years of follow up.


Assuntos
Nervo Facial/anormalidades , Nervo Facial/cirurgia
20.
Acta odontol. venez ; 49(1)2011. tab
Artigo em Espanhol | LILACS | ID: lil-678851

RESUMO

Los tumores neurales son lesiones oriundas de los nervios periféricos, siendo raros en la cavidad bucal. Estas lesiones incluyen el neurofibroma, neuroma traumático, schwanoma tumor de células granulares y el neuroma encapsulado. Objetivo: El presente trabajo se propuso a estudiar la prevalencia de estos tumores en dos servicios de diagnostico oral. Material y Método: fue realizado, a través de análisis de informes histopatológicos, un estudio retrospectivo de los casos de tumores neurales solitarios en la cavidad bucal diagnosticados en el laboratorio de Patología de la Universidad de Pernambuco, en el período de 1.992 a 2.007, y en el servicio de Patología de la Universidad Federal de Sergipe, en el periodo de 2.000 a 2.007. Resultados: Fueron encontrados 28 tumores neurales benignos, de un total de 4,485 informes analizados. De una manera general, el género femenino fue el más afectado y la lengua el sitio de mayor predilección. Hubo una discreta tendencia del surgimiento de las lesiones en la 1ª, 2ª e 3ª Décadas de vida. Conclusión: el conocimiento de estas lesiones, aunque raras en la cavidad bucal, se torna imprescindible para los profesionales del área odontológica, visto que las estrategias de diagnostico y tratamiento son dependientes de los datos epidemiológicos encontrados en la literatura especializada


Peripheral nerve sheath tumors rarely occur in the oral cavity and include neurofibroma, traumatic neuroma, schwannoma, granular cell tumor and palisaded encapsulated neuroma. Aim: The purpose of the present study was to determine the prevalence of these tumors in patients referred in two oral diagnostic services. Material and Method: Specimens diagnosed as oral peripheral nerve sheath tumors archived in the oral pathology services of Universidade de Pernambuco, from 1992 to 2007, and Universidade Federal de Sergipe, from 2000 to 2007, were evaluated. Results: Twentyeight peripheral nerve sheath tumors were diagnosed. Neurofibroma was the tumor more prevalent, including 40% of the cases. In general, females were more affected than males and the most frequent oral site was the tongue. Children and young people were more prevalent. Conclusion: The knowledge of these lesions, even though rare in oral cavity, it is essential for dentistry professionals, since that diagnosis and treatment strategies are dependents to epidemiological data founded in the literature


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Adulto Jovem , Pessoa de Meia-Idade , Neoplasias de Cabeça e Pescoço/patologia , Nervos Periféricos , Neoplasias Bucais/diagnóstico
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