Effect of niobium content on the microstructure and Young's modulus of Ti-xNb-7Zr alloys for medical implants.

New generation titanium alloys with low elastic moduli are promising materials for medical implants, particularly load-bearing orthopaedic implants. In this paper, the effect of niobium content on the microstructure and mechanical properties of new Ti alloys including Ti-23Nb-7Zr, Ti-28Nb-7Zr and Ti-33Nb-7Zr (wt%) is studied. Ti-23Nb-7Zr was found to mainly form α΄ and α″- phases, while both the Ti-28Nb-7Zr and Ti-33Nb-7Zr consisted of α″ and ß-phases with an increased amount of ß-phase in the alloy with 33 wt% of Nb. X-ray diffraction and microstructural analyses showed that the addition of Nb stabilises the ß-phase in the solution treated condition with the depleting amount of α΄ and α″- phases. The hardness and Young's modulus values were highest in Ti-23Nb-7Zr which is attributed to the high fraction of α΄- phase in this alloy. The Young's moduli achieved for the three alloys through nanoindentation were 35.9, 29.1 and 29.0 GPa, respectively. The new alloys are encouraging candidates for orthopaedic implants due to their low elastic modulus which can help inhibit stress shielding, although biocompatibility tests (in-vitro and in-vivo) are suggested for future work.

Development of Ti-Nb-Zr alloys with high elastic admissible strain for temporary orthopedic devices.

A new series of beta Ti-Nb-Zr (TNZ) alloys with considerable plastic deformation ability during compression test, high elastic admissible strain, and excellent cytocompatibility have been developed for removable bone tissue implant applications. TNZ alloys with nominal compositions of Ti-34Nb-25Zr, Ti-30Nb-32Zr, Ti-28Nb-35.4Zr and Ti-24.8Nb-40.7Zr (wt.% hereafter) were fabricated using the cold-crucible levitation technique, and the effects of alloying element content on their microstructures, mechanical properties (tensile strength, yield strength, compressive yield strength, Young's modulus, elastic energy, toughness, and micro-hardness), and cytocompatibilities were investigated and compared. Microstructural examinations revealed that the TNZ alloys consisted of ß phase. The alloy samples displayed excellent ductility with no cracking, or fracturing during compression tests. Their tensile strength, Young's modulus, elongation at rupture, and elastic admissible strain were measured in the ranges of 704-839 MPa, 62-65 GPa, 9.9-14.8% and 1.08-1.31%, respectively. The tensile strength, Young's modulus and elongation at rupture of the Ti-34Nb-25Zr alloy were measured as 839 ± 31.8 MPa, 62 ± 3.6 GPa, and 14.8 ± 1.6%, respectively; this alloy exhibited the elastic admissible strain of approximately 1.31%. Cytocompatibility tests indicated that the cell viability ratios (CVR) of the alloys are greater than those of the control group; thus the TNZ alloys possess excellent cytocompatibility.