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1.
Philos Trans A Math Phys Eng Sci ; 379(2189): 20200022, 2021 Jan 25.
Artigo em Inglês | MEDLINE | ID: mdl-33280560

RESUMO

When high-energy and high-power lasers interact with matter, a significant part of the incoming laser energy is transformed into transient electromagnetic pulses (EMPs) in the range of radiofrequencies and microwaves. These fields can reach high intensities and can potentially represent a significative danger for the electronic devices placed near the interaction point. Thus, the comprehension of the origin of these electromagnetic fields and of their distribution is of primary importance for the safe operation of high-power and high-energy laser facilities, but also for the possible use of these high fields in several promising applications. A recognized main source of EMPs is the target positive charging caused by the fast-electron emission due to laser-plasma interactions. The fast charging induces high neutralization currents from the conductive walls of the vacuum chamber through the target holder. However, other mechanisms related to the laser-target interaction are also capable of generating intense electromagnetic fields. Several possible sources of EMPs are discussed here and compared for high-energy and high-intensity laser-matter interactions, typical for inertial confinement fusion and laser-plasma acceleration. The possible effects on the electromagnetic field distribution within the experimental chamber, due to particle beams and plasma emitted from the target, are also described. This article is part of a discussion meeting issue 'Prospects for high gain inertial fusion energy (part 2)'.

2.
Proc Natl Acad Sci U S A ; 115(25): 6335-6340, 2018 06 19.
Artigo em Inglês | MEDLINE | ID: mdl-29871946

RESUMO

In the field of X-ray microcomputed tomography (µCT) there is a growing need to reduce acquisition times at high spatial resolution (approximate micrometers) to facilitate in vivo and high-throughput operations. The state of the art represented by synchrotron light sources is not practical for certain applications, and therefore the development of high-brightness laboratory-scale sources is crucial. We present here imaging of a fixed embryonic mouse sample using a compact laser-plasma-based X-ray light source and compare the results to images obtained using a commercial X-ray µCT scanner. The radiation is generated by the betatron motion of electrons inside a dilute and transient plasma, which circumvents the flux limitations imposed by the solid or liquid anodes used in conventional electron-impact X-ray tubes. This X-ray source is pulsed (duration <30 fs), bright (>1010 photons per pulse), small (diameter <1 µm), and has a critical energy >15 keV. Stable X-ray performance enabled tomographic imaging of equivalent quality to that of the µCT scanner, an important confirmation of the suitability of the laser-driven source for applications. The X-ray flux achievable with this approach scales with the laser repetition rate without compromising the source size, which will allow the recording of high-resolution µCT scans in minutes.


Assuntos
Radiografia/métodos , Microtomografia por Raio-X/métodos , Animais , Desenho de Equipamento , Lasers , Luz , Camundongos/embriologia , Aceleradores de Partículas , Fótons , Espalhamento de Radiação , Raios X
3.
Philos Trans A Math Phys Eng Sci ; 377(2151): 20180419, 2019 Aug 12.
Artigo em Inglês | MEDLINE | ID: mdl-31230574

RESUMO

A linear electron-positron collider operating at TeV-scale energies will provide high precision measurements and allow, for example, precision studies of the Higgs boson as well as searches for physics beyond the standard model. A future linear collider should produce collisions at high energy, with high luminosity and with a good wall plug to beam power transfer efficiency. The luminosity per power consumed is a key metric that can be used to compare linear collider concepts. The plasma wakefield accelerator has demonstrated high-gradient, high-efficiency acceleration of an electron beam and is therefore a promising technology for a future linear collider. We will go through the opportunities of using plasma wakefield acceleration technology for a collider, as well as a few of the collider-specific challenges that must be addressed in order for a high-energy, high luminosity-per-power plasma wakefield collider to become a reality. This article is part of the Theo Murphy meeting issue 'Directions in particle beam-driven plasma wakefield acceleration'.

4.
Philos Trans A Math Phys Eng Sci ; 372(2010): 20130032, 2014 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-24470414

RESUMO

Advances in X-ray imaging techniques have been driven by advances in novel X-ray sources. The latest fourth-generation X-ray sources can boast large photon fluxes at unprecedented brightness. However, the large size of these facilities means that these sources are not available for everyday applications. With advances in laser plasma acceleration, electron beams can now be generated at energies comparable to those used in light sources, but in university-sized laboratories. By making use of the strong transverse focusing of plasma accelerators, bright sources of betatron radiation have been produced. Here, we demonstrate phase-contrast imaging of a biological sample for the first time by radiation generated by GeV electron beams produced by a laser accelerator. The work was performed using a greater than 300 TW laser, which allowed the energy of the synchrotron source to be extended to the 10-100 keV range.

5.
Med Phys ; 39(6Part17): 3813-3814, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28517464

RESUMO

PURPOSE: Progress in the development of compact high-energy pulsed laser- plasma wakefield accelerators is opening up the potential for using Very High Energy Electron (VHEEs) beams in the range of 150 - 250 MeV for biomedical studies. Initial experiments using VHEE for this purpose have been carried out using the ALPHA-X laser-plasma wakefield accelerator beam line at the University of Strathclyde, Glasgow, UK. The purpose of this investigation is to use Monte Carlo simulations to plan experiments and compare with characterization of the interaction of the VHEE beam using a dosimeter. METHODS: An experiment using the VHEE beam to irradiate a muscle-equivalent BANG polymer gel dosimeter has been carried out. Simulations have been used to prepare for the experiments. These were undertaken using the expected average energy for a pulse set and an energy spread approximated by Gaussian distribution. The model was implemented in FLUKA Monte Carlo code with follow up modeling using the Geant4 toolkit. The results have been compared with 1mm̂3 voxel laser CT based measurements of the dose deposited in the BANG dosimeter and with measurement of the induced radioactivity. RESULTS: The results of the measured dose from induced radioactivity have been compared with data from the FLUKA simulations. The beam model based on an average energy of particles in irradiation gives an acceptable estimate of the induced radioactivity and the dose deposited in the BANG dosimeter. Comparison with the dosimeter scanned profiles shows that the structure of the spectra of VHEE beams in the experiment and secondary scattered particles in the beam line should be accounted for in any model. Such model description of the VHEE beam for the ALPHA-X beam line has been developed. CONCLUSIONS: Monte Carlo simulations using the FLUKA code is an efficient way to plan a VHEE experiment and analyze data from measurements.

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