Pesquisa | BVS IEC

1.

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.

Neurohr, Gabriel E; Terry, Rachel L; Lengefeld, Jette; Bonney, Megan; Brittingham, Gregory P; Moretto, Fabien; Miettinen, Teemu P; Vaites, Laura Pontano; Soares, Luis M; Paulo, Joao A; Harper, J Wade; Buratowski, Stephen; Manalis, Scott; van Werven, Folkert J; Holt, Liam J; Amon, Angelika.

Cell ; 176(5): 1083-1097.e18, 2019 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-30739799

2.

Targeting the adaptability of heterogeneous aneuploids.

Chen, Guangbo; Mulla, Wahid A; Kucharavy, Andrei; Tsai, Hung-Ji; Rubinstein, Boris; Conkright, Juliana; McCroskey, Scott; Bradford, William D; Weems, Lauren; Haug, Jeff S; Seidel, Chris W; Berman, Judith; Li, Rong.

Cell ; 160(4): 771-784, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25679766

3.

Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.

Schwartz, Schraga; Bernstein, Douglas A; Mumbach, Maxwell R; Jovanovic, Marko; Herbst, Rebecca H; León-Ricardo, Brian X; Engreitz, Jesse M; Guttman, Mitchell; Satija, Rahul; Lander, Eric S; Fink, Gerald; Regev, Aviv.

Cell ; 159(1): 148-162, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25219674

4.

Genomic Approaches to Antifungal Drug Target Identification and Validation.

Robbins, Nicole; Cowen, Leah E.

Annu Rev Microbiol ; 76: 369-388, 2022 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-35650665

5.

A recently evolved transcriptional network controls biofilm development in Candida albicans.

Nobile, Clarissa J; Fox, Emily P; Nett, Jeniel E; Sorrells, Trevor R; Mitrovich, Quinn M; Hernday, Aaron D; Tuch, Brian B; Andes, David R; Johnson, Alexander D.

Cell ; 148(1-2): 126-38, 2012 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-22265407

6.

Identification of an active RNAi pathway in Candida albicans.

Iracane, Elise; Arias-Sardá, Cristina; Maufrais, Corinne; Ene, Iuliana V; d'Enfert, Christophe; Buscaino, Alessia.

Proc Natl Acad Sci U S A ; 121(17): e2315926121, 2024 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-38625945

7.

Biofilm-associated metabolism via ERG251 in Candida albicans.

Xiong, Liping; Pereira De Sa, Nivea; Zarnowski, Robert; Huang, Manning Y; Mota Fernandes, Caroline; Lanni, Frederick; Andes, David R; Del Poeta, Maurizio; Mitchell, Aaron P.

PLoS Pathog ; 20(5): e1012225, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38739655

8.

A gain-of-function mutation in zinc cluster transcription factor Rob1 drives Candida albicans adaptive growth in the cystic fibrosis lung environment.

Gnaien, Mayssa; Maufrais, Corinne; Rebai, Yasmine; Kallel, Aicha; Ma, Laurence; Hamouda, Samia; Khalsi, Fatma; Meftah, Khaoula; Smaoui, Hanen; Khemiri, Monia; Hadj Fredj, Sondes; Bachellier-Bassi, Sophie; Najjar, Imène; Messaoud, Taieb; Boussetta, Khadija; Kallel, Kalthoum; Mardassi, Helmi; d'Enfert, Christophe; Bougnoux, Marie-Elisabeth; Znaidi, Sadri.

PLoS Pathog ; 20(4): e1012154, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38603707

9.

Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease.

Anderson, Faith M; Visser, Noelle D; Amses, Kevin R; Hodgins-Davis, Andrea; Weber, Alexandra M; Metzner, Katura M; McFadden, Michael J; Mills, Ryan E; O'Meara, Matthew J; James, Timothy Y; O'Meara, Teresa R.

PLoS Biol ; 21(5): e3001822, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37205709

10.

Cell-type memory in a single-cell eukaryote requires the continuous presence of a specific transcription regulator.

Lee, Chien-Der; Ziv, Naomi; Johnson, Alexander D.

Proc Natl Acad Sci U S A ; 120(21): e2220568120, 2023 05 23.

Artigo em Inglês | MEDLINE | ID: mdl-37186823

11.

The Ypk1 protein kinase signaling pathway is rewired and not essential for viability in Candida albicans.

Ramírez-Zavala, Bernardo; Krüger, Ines; Wollner, Andreas; Schwanfelder, Sonja; Morschhäuser, Joachim.

PLoS Genet ; 19(8): e1010890, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37561787

12.

The glycerophosphocholine acyltransferase Gpc1 contributes to phosphatidylcholine biosynthesis, long-term viability, and embedded hyphal growth in Candida albicans.

King, William R; Singer, Justin; Warman, Mitchell; Wilson, Duncan; Hube, Bernard; Lager, Ida; Patton-Vogt, Jana.

J Biol Chem ; 300(1): 105543, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38072057

13.

The transcription factor Ofi1 is critical for white-opaque switching in natural MTLa/α isolates of Candida albicans.

Cui, Hao; Yang, Dandan; Gong, Shengwei; Zhang, Yaling; Dong, Bin; Su, Chang; Yang, Lianjuan; Lu, Yang.

Mol Microbiol ; 121(2): 275-290, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-38167837

14.

RFX transcription factor in the human-associated yeast Candida albicans regulates adhesion to oral epithelium.

Rodríguez, Diana L; Lindemann-Perez, Elena; Perez, J Christian.

Mol Microbiol ; 121(4): 727-741, 2024 04.

Artigo em Inglês | MEDLINE | ID: mdl-38183361

15.

Integrated post-genomic cell wall analysis reveals floating biofilm formation associated with high expression of flocculins in the pathogen Pichia kudriavzevii.

Alvarado, María; Gómez-Navajas, Jesús Alberto; Blázquez-Muñoz, María Teresa; Gómez-Molero, Emilia; Berbegal, Carmen; Eraso, Elena; Kramer, Gertjan; De Groot, Piet W J.

PLoS Pathog ; 19(5): e1011158, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37196016

16.

Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network.

Cravener, Max V; Do, Eunsoo; May, Gemma; Zarnowski, Robert; Andes, David R; McManus, C Joel; Mitchell, Aaron P.

PLoS Pathog ; 19(1): e1011109, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36696432

17.

Structural analysis of the Candida albicans mitochondrial DNA maintenance factor Gcf1p reveals a dynamic DNA-bridging mechanism.

Tarrés-Solé, Aleix; Battistini, Federica; Gerhold, Joachim M; Piétrement, Olivier; Martínez-García, Belén; Ruiz-López, Elena; Lyonnais, Sébastien; Bernadó, Pau; Roca, Joaquim; Orozco, Modesto; Le Cam, Eric; Sedman, Juhan; Solà, Maria.

Nucleic Acids Res ; 51(11): 5864-5882, 2023 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-37207342

18.

Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process.

Rizzo, Marzia; Soisangwan, Natthapon; Vega-Estevez, Samuel; Price, Robert Jordan; Uyl, Chloe; Iracane, Elise; Shaw, Matt; Soetaert, Jan; Selmecki, Anna; Buscaino, Alessia.

PLoS Genet ; 18(12): e1010576, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36574460

19.

A common vesicle proteome drives fungal biofilm development.

Zarnowski, Robert; Sanchez, Hiram; Jaromin, Anna; Zarnowska, Urszula J; Nett, Jeniel E; Mitchell, Aaron P; Andes, David.

Proc Natl Acad Sci U S A ; 119(38): e2211424119, 2022 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-36095193

20.

Cek1 regulates ß(1,3)-glucan exposure through calcineurin effectors in Candida albicans.

Wagner, Andrew S; Lumsdaine, Stephen W; Mangrum, Mikayla M; King, Ainsley E; Hancock, Trevor J; Sparer, Timothy E; Reynolds, Todd B.

PLoS Genet ; 18(9): e1010405, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36121853

BVS IEC

Instituto Evandro Chagas

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