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6.
Poult Sci ; 47(4): 1377-9, 1968 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-5749598
7.
Biochem J ; 104(2): 519-23, 1967 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-6048793

RESUMO

1. Starvation did not affect the rates of glucose utilization or lactate formation by guinea-pig cerebral cortex slices. 2. Palmitate (1mm), butyrate (5mm) or acetoacetate (5mm) did not affect glucose utilization or lactate formation by cerebral cortex slices from guinea pigs starved for 48hr. 3. dl-beta-Hydroxybutyrate (10mm) increased the formation of lactate without affecting glucose utilization by cerebral cortex slices from guinea pigs starved for 48hr. This implies that beta-hydroxybutyrate decreased the rate of glucose oxidation. 4. Metabolism of added ketone bodies can account for 20-40% of observed rates of oxygen consumption. 5. Lactate or pyruvate (5mm) decreased the rates of glucose utilization by guinea-pig cerebral cortex slices.


Assuntos
Córtex Cerebral/efeitos dos fármacos , Ácidos Graxos/farmacologia , Glucose/metabolismo , Corpos Cetônicos/farmacologia , Lactatos/farmacologia , Piruvatos/farmacologia , Acetoacetatos/farmacologia , Animais , Butiratos/farmacologia , Feminino , Cobaias , Masculino , Consumo de Oxigênio/instrumentação , Ácidos Palmíticos/farmacologia , Inanição/metabolismo
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