RESUMO
BACKGROUND: Although syringoma is a common benign tumour of the sudoriferous gland, there is also an extremely rare malignant form known as syringoid eccrine carcinoma (SEC). SEC usually exhibits slow growth with deep invasion and a frequent tendency to relapse. The treatment of choice is radical wide resection, which poses a difficult reconstructive problem, especially when the tumour is located in the centre of the face. CASE PRESENTATION: In this case, a 70-year-old man was diagnosed with an SEC at the same location as a benign syringoma of the upper lip and nasal base that had undergone primary excision 7 years prior. Primary radical resection was performed with immediate Abbé flap reconstruction. Nevertheless, histology revealed positive margins, and 3 additional re-excisions were needed to achieve clear margins. Four months after the initial resection, the patient had undergone an innovative reconstruction technique including not only the Abbé flap but also a turbinate flap harvested with functional endonasal surgery and a three-stage forehead flap. CONCLUSION: To the best of our knowledge, this is the first case report of a suspect malignant transformation of a benign syringoma after 7 years. In addition, from oncoplastic and reconstructive points of view, the bilateral use of the turbinate flap for reconstructing the intranasal lining of the alar base is unusual, and the use of functional endonasal surgery in nasal reconstruction for reducing the risk of damaging the vascular supply of the flap is innovative.
Assuntos
Carcinoma , Procedimentos de Cirurgia Plástica , Neoplasias das Glândulas Sudoríparas , Siringoma , Idoso , Carcinoma/cirurgia , Testa/cirurgia , Humanos , Lábio/cirurgia , Masculino , Recidiva Local de Neoplasia/cirurgia , Neoplasias de Anexos e de Apêndices Cutâneos , Procedimentos de Cirurgia Plástica/métodos , Neoplasias Cutâneas , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Conchas Nasais/cirurgiaRESUMO
Syringomatous adenoma of the nipple is a rare benign infiltrative neoplasm that was first described in 1983. At the time of this writing, a literature search revealed no cases of syringomatous adenoma of the nipple in association with invasive carcinoma of the breast. We report a case of syringomatous adenoma of the nipple in a 40-year old female who also had bilateral invasive ductal carcinoma and ductal carcinoma in situ of the breasts. Syringomatous adenomas of the nipple have been postulated to originate from eccrine structures of the nipple due to their microscopic similarity to other tumors of eccrine origin, such as syringomatous carcinoma. However, their exact origin is uncertain. Despite their benign behavior, they usually demonstrate an infiltrative and expansile proliferation into adjacent nipple and breast tissue. They have been confused with tubular carcinoma and low-grade adenosquamous carcinoma of the breast, both clinically and histologically. Complete excision is the therapy of choice, and only incompletely excised lesions have shown recurrence. We present this case to raise awareness that syringomatous adenoma of the nipple may present in patients with a simultaneous invasive carcinoma of the breast.
Assuntos
Adenocarcinoma , Adenoma , Neoplasias da Mama , Neoplasias das Glândulas Sudoríparas , Siringoma , Feminino , Humanos , Adulto , Mamilos/patologia , Siringoma/diagnóstico , Siringoma/cirurgia , Siringoma/patologia , Adenoma/diagnóstico , Adenoma/cirurgia , Adenocarcinoma/patologia , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/cirurgia , Neoplasias das Glândulas Sudoríparas/patologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologiaRESUMO
BACKGROUND: Syringoma is a common benign tumor with eccrine origin that typically occurs on the face of middle-aged women. Laser ablation with CO2 laser or Er:YAG laser has been widely used in the clinical field, often leading to scars due to its deep location. This study aimed to investigate clinical characteristics and pathological depths of the lesions in syringoma patients. MATERIALS AND METHODS: Syringoma patients, pathologically confirmed at Samsung medical center (Seoul, Korea) from January 1996 to March 2019, were analyzed. Clinical characteristics such as the location of lesion, age, and sex, and pathological depths of the lesions were investigated, and univariable and multivariable analyses were done for these factors. RESULTS: Of total 94 syringomas, 17.0% were located on periocular area, 10.6% on forehead, 34.0% on head and neck areas excluding periocular area and forehead, and 38.3% on trunk and extremities. The mean depth of syringoma from the surface including stratum corneum to the deepest stromal location was 1174.14 ± 1142.95 µm for periocular area, 1055.93 ± 247.76 µm for forehead, 1488.06 ± 1217.36 µm for other areas of head and neck including scalp, and 1169.53 ± 349.2 for the lesions located at trunk and extremities including external genitalia. No significant correlation was observed from univariable analysis and multivariable analysis by age, sex, and site of lesion. CONCLUSION: Our findings offer valuable information of the mean depth of syringoma at different sites, which can be taken into consideration for successful treatment without adverse events such as scarring.
Assuntos
Terapia a Laser , Lasers de Estado Sólido , Neoplasias das Glândulas Sudoríparas , Siringoma , Feminino , Humanos , Pessoa de Meia-Idade , República da Coreia/epidemiologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgiaRESUMO
BACKGROUND: Conventional treatment options for periorbital syringomas are often unsatisfactory because of inevitable surface damage from the procedure and frequent recurrence rate of the tumors. OBJECTIVES: The authors sought to ascertain the efficacy and safety of intralesional electrosurgery utilizing a monopolar radiofrequency device with a single insulated microneedle for the treatment of periorbital syringomas. METHODS: A retrospective analysis was performed employing data from medical records, routine questionnaires, and clinical photographs of 55 patients with periorbital syringoma who underwent intralesional electrosurgery. RESULTS: Approximately one-half of the patients (50.9%) experienced marked resolution after 1 treatment. The lesion clearance rate increased and lesion severity decreased each time the treatment was repeated. No persistent therapy-related adverse event was found except transient erythema or crusting. CONCLUSIONS: Intralesional electrosurgery with insulated microneedle is an effective and safe treatment option for periorbital syringomas.
Assuntos
Neoplasias das Glândulas Sudoríparas , Siringoma , Eletrocoagulação/efeitos adversos , Humanos , Recidiva Local de Neoplasia , Estudos Retrospectivos , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgiaRESUMO
Infiltrating syringomatous adenoma of the nipple (SAN) is a rare benign neoplasm of the breast that is often misdiagnosed. SAN may present with a subareolar lesion and clinical, mammographic, and ultrasonographic findings associated with malignancy. We present the case of a 60-year-old woman with a painful, firm, solid tumor in her left breast and deformation of the left nipple-areolar complex (NAC). Histopathological test results were conflicting. The tumor, including the NAC were locally excised. Postsurgical immuno-histochemical tests revealed squamous histology, whereas myoepithelial cells were present in the resected specimen, a feature consistent with SAN. The pathologist noted microscopically positive surgical margins. Three months after surgery, tumor recurrence occurred. The patient underwent revision surgery with wide excision of the skin and gland around the lesion, followed by immediate breast reconstruction, using a pedicled myocutaneous latissimus dorsi (pLD) flap. Extreme care should be taken when diagnosing SAN to ensure proper treatment and prevent recurrence.
Assuntos
Adenoma/cirurgia , Erros de Diagnóstico/efeitos adversos , Recidiva Local de Neoplasia/cirurgia , Mamilos/cirurgia , Siringoma/cirurgia , Adenoma/patologia , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Feminino , Humanos , Mamoplastia , Mamografia , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Mamilos/patologia , Papiloma/patologia , Papiloma/cirurgia , Siringoma/diagnóstico , Siringoma/patologia , Resultado do TratamentoRESUMO
Syringoma is a benign adnexal tumor originating from the intradermal eccrine ducts and predominantly occurs in women at puberty or later in life. We present a case of a 30-year-old woman with a 2-year history of syringoma on her neck and axillar region. She was treated with two devices in a split manner. The right-sided lesions of the neck were treated with one session of 10,600-nm carbon dioxide (CO2 ) laser ablation. The left-sided lesions were treated with microinsulated needle radiofrequency (RF) three times. After treatment, the lesions treated with CO2 showed hypertrophic scar formation, but the other side lesions treated with microinsulated needle RF showed a marked reduction in the size and number of lesions, without any adverse effects such as scarring and hyperpigmentation related to epidermal damage. The treatment of syringoma with microinsulated needle RF, which is insulated at the point of epidermal contact, results in good cosmetic outcomes. Syringoma, microinsulated needle RF, CO2 laser.
Assuntos
Ablação por Cateter/métodos , Lasers de Gás/uso terapêutico , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Adulto , Feminino , Humanos , Ondas de RádioRESUMO
BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare, locally aggressive cutaneous neoplasm that commonly occurs on the face. OBJECTIVE: The purpose of this article is to comprehensively review the current literature on MAC pertaining to epidemiology, pathogenesis, clinical presentation, histology, immunohistochemistry, prognosis, follow-up, and treatment. MATERIALS AND METHODS: An extensive literature review was conducted using OVID MEDLINE and PubMed to identify articles relating to MAC. RESULTS: Microcystic adnexal carcinoma typically presents as a skin-colored nodule on the face. The pathogenesis is mostly related to pilar and eccrine differentiation. Histologically, MAC can mimic syringoma, desmoplastic trichoepithelioma, and infiltrative basal cell carcinoma. Diagnosis is challenging because superficial shave biopsies may reveal only benign findings that do not warrant further management. A deep biopsy is mandatory for the correct diagnosis, and Mohs micrographic surgery provides the highest cure rate. CONCLUSION: Microcystic adnexal carcinoma is a locally aggressive disease with histological margins that often far surpass what is clinically suspected. Mohs micrographic surgery is the standard of care for removal of these lesions. Patients with a history of MAC should be examined at least every 6 months for recurrence, metastasis, and development of additional skin cancers.
Assuntos
Neoplasias Faciais , Neoplasias Cutâneas , Siringoma , Neoplasias Faciais/epidemiologia , Neoplasias Faciais/metabolismo , Neoplasias Faciais/patologia , Neoplasias Faciais/cirurgia , Humanos , Imuno-Histoquímica , Prognóstico , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/metabolismo , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Siringoma/epidemiologia , Siringoma/metabolismo , Siringoma/patologia , Siringoma/cirurgiaRESUMO
BACKGROUND: The 1,444 nm wavelength is also well absorbed in water making it a possible setting for treatment of cystic lesions such as eccrine hydrocystomas and syringomas. OBJECTIVE: The authors aimed to investigate the efficacy of an externally used 1,444 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for the treatment of periorbital syringomas. METHODS AND MATERIALS: Nineteen patients with periorbital syringomas were treated twice with the externally used 1,444 nm Nd:YAG laser at 2-month intervals. Laser fluences were delivered to each papule with pulse energy of 160 mJ, 1.6 W of power, and at a 10 Hz pulse rate. Clinical improvement and patient satisfaction were assessed at 2 and 6 months after each treatment. Side effects were also examined. RESULTS: Clinical improvement of >50% was observed in 68.4% of individuals at 2 months after first treatment (2FT) and in all patients at 6 months after second treatment (6ST). Patient satisfaction of no less than "satisfied" was recorded for 63.2% of patients at 2FT, and in 89.5% of patients at 6ST. Erythema was observed in 63.2% of patients but only at 2FT. CONCLUSION: Externally used 1,444 nm Nd:YAG laser treatment may represent an effective and safe approach for the treatment of periorbital syringomas, resulting in good satisfaction and minimal side effects.
Assuntos
Lasers de Estado Sólido/uso terapêutico , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Adulto , Alumínio , Feminino , Seguimentos , Humanos , Lasers de Estado Sólido/efeitos adversos , Pessoa de Meia-Idade , Satisfação do Paciente , Córtex Pré-Frontal/patologia , Córtex Pré-Frontal/cirurgia , Estudos Retrospectivos , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Resultado do Tratamento , ÍtrioRESUMO
Longitudinal splitting of the nails can occur as a result of any growth arising in the nail matrix. We present a case of a 50-year-old woman who presented with an 18-month history of longitudinal splitting of the nail on her right little finger, along with pain in the proximal nail fold region, which was extremely tender to touch. Magnetic resonance imaging revealed an intensely enhancing lesion, while colour Doppler imaging revealed hypervascularity within the mass. A provisional diagnosis of glomus tumour was considered. Histopathology demonstrated presence of a well-circumscribed tumour comprising a dual population of cells, which stained negatively with periodic-acid-Schiff. The histopathological features were consistent with those of eccrine spiradenoma (ES). In this case, glomus tumour was considered as the first differential diagnosis, but histopathology confirmed it as an ES.
Assuntos
Doenças da Unha/etiologia , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Doenças da Unha/patologia , Doenças da Unha/cirurgia , Neoplasias das Glândulas Sudoríparas/diagnóstico por imagem , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/diagnóstico por imagem , Siringoma/cirurgiaRESUMO
BACKGROUND: Although various destructive methods have been described for treating syringomas, they are often associated with significant scarring and recurrence. In 2007, multiple-drilling method using carbon dioxide (CO2) laser was introduced as an alternative modality to gain good cosmetic results. OBJECTIVE: To retrospectively evaluate the effectiveness of CO2 laser combined with botulinum toxin A (BTXA) as treatment for syringomas. MATERIAL AND METHODS: Forty-eight patients with periorbital syringomas were treated with topical application of BTXA immediately after CO2 laser treatment. Forty-four patients were treated with CO2 laser only. RESULTS: Patients who were treated with CO2 laser combined with BTXA required significantly (p = 0.038) fewer treatment sessions compared with those treated with CO2 laser only. When the clinical improvements of the two treatment sessions were compared, the combined therapy (CO2 laser and BTXA) had significantly (p = 0.044) higher rate of results showing good (disappearance of 60-80% of lesion) or excellent (80-100%) than the CO2 laser only therapy (87.5% vs. 70.5%). CONCLUSIONS: CO2 laser combined with BTXA showed better effect than CO2 laser only.
Assuntos
Toxinas Botulínicas Tipo A/administração & dosagem , Neoplasias Palpebrais/terapia , Terapia a Laser/métodos , Fármacos Neuromusculares/administração & dosagem , Neoplasias das Glândulas Sudoríparas/terapia , Siringoma/terapia , Terapia Combinada , Neoplasias Palpebrais/cirurgia , Feminino , Humanos , Masculino , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgiaRESUMO
Penile syringomas are benign adnexal tumors that are usually asymptomatic but can be cosmetically distressing. Because of the delicate nature of skin in this region, treatment is difficult, and there are few case reports of procedural destruction of these tumors. We report a case of successful surgical excision using Castroviejo ophthalmic scissors followed by primary closure with fast-absorbing plain gut suture and a cyanoacrylate adhesive application. This procedure was well tolerated and had an impressive cosmetic outcome.
Assuntos
Neoplasias Penianas/cirurgia , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Adesivos , Adolescente , Humanos , Masculino , Microcirurgia , Neoplasias Penianas/patologia , Suturas , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , CicatrizaçãoRESUMO
Syringomatous tumor of the nipple is a benign, locally infiltrative tumor. There are reports in the literature of tumor recurrence in cases of incomplete excision. Clinical and mammographic findings in syringomatous tumors are like those of breast carcinoma and the pathologist has a fundamental role in final tumor diagnosis. Therefore, the aim of this study was to report a case of syringoma located in the areolar region. A 33-year-old woman reported that she had noticed a nodule in her left areolar region 4 years previously (February 2019). A breast ultrasound was performed, detecting intraparenchymatous breast cysts. Surgical resection of the nodule was indicated although it was not performed. Two years later, in August 2021, the patient underwent a mastopexy with prosthesis inclusion. Histopathology study of the surgical specimen revealed a syringomatous tumor with positive margins. Thirteen (13) months after diagnosis (September 3, 2021 - October 16, 2022), the patient is doing well and receives clinical follow-up.
Assuntos
Neoplasias da Mama , Mamilos , Siringoma , Ultrassonografia Mamária , Humanos , Feminino , Adulto , Neoplasias da Mama/patologia , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/cirurgia , Mamilos/patologia , Siringoma/patologia , Siringoma/diagnóstico , Siringoma/cirurgia , Neoplasias das Glândulas Sudoríparas/patologia , Neoplasias das Glândulas Sudoríparas/diagnóstico , Neoplasias das Glândulas Sudoríparas/cirurgia , Seguimentos , Mamoplastia/métodosAssuntos
Carcinoma Basocelular/patologia , Carcinoma Basocelular/cirurgia , Neoplasias Labiais/patologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Neoplasias das Glândulas Sudoríparas/patologia , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/patologia , Siringoma/cirurgia , Adulto , Biópsia , Diagnóstico Diferencial , Humanos , Neoplasias Labiais/cirurgia , Masculino , Cirurgia de MohsRESUMO
Combined tumours are often a serendipitous finding. Among the spectrum of melanocytic tumours, the co-existence of different cell populations of the same lineage is a well-recognised phenomenon. Less commonly documented, but still well documented is the event of a melanocytic tumour in collision with an epithelial benign or malignant neoplasm. Exceptionally infrequent is however the collision of a Spitz naevus with an epithelial tumour. Here we report the clinical-dermoscopic and histopathological findings of a Spitz naevus occurring in collision with a syringoma.
Assuntos
Neoplasias Complexas Mistas/patologia , Nevo de Células Epitelioides e Fusiformes/patologia , Neoplasias Cutâneas/patologia , Siringoma/patologia , Adulto , Humanos , Masculino , Neoplasias Complexas Mistas/cirurgia , Nevo de Células Epitelioides e Fusiformes/cirurgia , Neoplasias Cutâneas/cirurgia , Siringoma/cirurgiaRESUMO
Syringocystadenocarcinoma papilliferum is the rare malignant counterpart of a more common, benign adnexal neoplasm known as syringocystadenoma papilliferum. Review of the literature identified 21 cases of syringocystadenocarcinoma papilliferum. Most reported SCACP seem to represent examples of in situ adenocarcinoma or invasive adenocarcinomas, whereas to our knowledge, only 3 cases were described as SCACP with squamous cell carcinoma. In the present series of 2 cases, we report of SCACP with squamous differentiation and 1 case of SCACP with regional lymph node metastasis. The risk of regional lymph node metastasis is low with SCACP, but it should be kept in mind for the risk of regional metastasis of its morphological type of invasive squamous cell carcinoma.
Assuntos
Carcinoma de Células Escamosas/patologia , Carcinoma de Células Escamosas/cirurgia , Cistadenocarcinoma Papilar/patologia , Cistadenocarcinoma Papilar/cirurgia , Testa/patologia , Couro Cabeludo/patologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgia , Siringoma/patologia , Siringoma/cirurgia , Idoso , Feminino , Humanos , Metástase Linfática , MasculinoRESUMO
Syringoma is a common but refractory benign skin tumor. Conventional treatment, such as ultra-pulsed carbon dioxide (CO2 ) laser or cryotherapy, often requires multiple treatment and can easily cause prolonged erythema, scarring, or depression, which are frustrating, so there is an urgent need to seek a safer and more effective method. In this article, we tried to demonstrate the Er:YAG laser combined with botulinum toxin A (BTXA) as a safer and more efficacious method for treating syringomas. MATERIALS AND METHODS: Twenty-one patients with local syringomas were treated with erbium laser ablation. Immediately after laser treatment, approximately 10 units of BTXA were sprayed on the wound for 10 min. RESULT: In total, 21 patients underwent 1.62 ± 0.74 treatments; their Periorbital Syringoma Severity Index (PSSI) score declined from 4.19 (before treatment) to 1.10 (after treatment), and the number of treatments was significantly lower than those reported in previous literature using the erbium laser alone. CONCLUSION: The Er:YAG laser combined with botulinum toxin A for the treatment of syringoma is a safer and more effective treatment than traditional treatment methods.
Assuntos
Toxinas Botulínicas Tipo A , Terapia a Laser , Lasers de Estado Sólido , Neoplasias das Glândulas Sudoríparas , Siringoma , Humanos , Siringoma/cirurgia , Toxinas Botulínicas Tipo A/efeitos adversos , Lasers de Estado Sólido/efeitos adversos , Érbio , Terapia a Laser/métodos , Neoplasias das Glândulas Sudoríparas/terapiaRESUMO
Syringomas are common benign eccrine ductal adnexial tumors, commonly found in periorbital area. Periorbital syringomas are aesthetically disturbing difficult to treat. Many treatment modalities are described in the literature, including topical and surgical methods, with potential problems such as postinflammatory hyper- and hypopigmentation, low efficacy, or scar formation. We present 5 patients with syringoma treated with the combination of radiofrequency ablation and carbon dioxide (CO2) lasers. Using low-energy parameters on the CO2 laser, and low energy on the radiofrequency, we could complement both treatments maximizing the destruction of the tumors and minimizing the adverse effects in only two sessions. This is a relatively easy, safe, and less painful treatment, with good cosmetic results on periorbital syringomas.
Assuntos
Ablação por Cateter/métodos , Lasers de Gás/uso terapêutico , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Ablação por Cateter/efeitos adversos , Cicatriz/etiologia , Terapia Combinada , Feminino , Humanos , Lasers de Gás/efeitos adversos , Masculino , Pessoa de Meia-Idade , Órbita , Resultado do TratamentoRESUMO
Syringomas are benign adnexal neoplasms that may induce psychological stress when they are large or disfiguring or present in delicate regions such as the periorbital area. Despite the availability of various lasers for syringomas, no consensus has been established on the optimal laser setting and side effects of these therapies. The current review aims at understanding the efficacy and safety of various laser therapies available for the treatment of syringomas. A literature search was carried out using PubMed and Ovid databases for articles published from Jan 2000 through Mar 2022. Screening the eligible articles yielded 27 studies, comprising clinical studies, case series, and case reports, which were included in this review. The CO2 laser is the most widely used ablative laser therapy but is usually associated with adverse events. Pinhole and multiple drilling methods using CO2 laser yielded excellent cosmetic results with minimal adverse effects. Fractional lasers reduced the downtime and complications compared to non-fractionated ones. Non-ablative fractional lasers could be advantageous in terms of easy operation, minimal side effects and moderate recovery period compared with ablative lasers. Large clinical trials are needed to generate strong evidence to guide clinicians in choosing the most appropriate laser therapy for syringoma treatment.
Assuntos
Terapia a Laser , Lasers de Gás , Neoplasias das Glândulas Sudoríparas , Siringoma , Humanos , Siringoma/cirurgia , Siringoma/etiologia , Neoplasias das Glândulas Sudoríparas/radioterapia , Neoplasias das Glândulas Sudoríparas/cirurgia , Dióxido de Carbono , Terapia a Laser/efeitos adversos , Terapia a Laser/métodos , Lasers de Gás/efeitos adversos , Resultado do TratamentoRESUMO
BACKGROUND: Treatment of syringoma aims to destroy the dermal tumor using methods that can include surgical excision, electrodessication, cryosurgery, chemical peeling, and laser ablation, but complete removal of syringomas is often unsuccessful, and recurrence occurs frequently. OBJECTIVE: To investigate the therapeutic efficacy of an ablative 10,600-nm carbon dioxide fractional laser system (CO(2) FS) for the treatment of periorbital syringomas. METHODS: Thirty-five patients with periorbital syringomas were treated with two sessions of CO(2) FS at 1-month intervals. Laser fluences were delivered in two or three passes over the lower eyelids, using a pulse energy of 100 mJ and a density of 100 spots/cm(2) . Clinical improvement was assessed by comparing pre- and post-treatment clinical photographs and patient satisfaction rates. We examined the histological features of human periorbital syringomas treated with CO(2) FS. RESULTS: Evaluation of clinical results 2 months after treatment showed that 15 of the 35 patients (42.9%) demonstrated marked (51-75%) clinical improvement, 12 (34.3%) had moderate (26-50%) clinical improvement, five (14.3%) showed minimal (0-25%) improvement, and three (8.6%) showed near total (≥75%) improvement. Clinical improvement scores were less 4 months after the second CO(2) FS treatment (not statistically significant). The mean maximal depth of the necrotic column was 1,236.3 µm. A specimen obtained from the infraorbital area immediately after treatment showed formation of necrotic columns on the interfollicular skin. CONCLUSION: The use of CO(2) FS can have a positive therapeutic effect on periorbital syringomas.
Assuntos
Terapia a Laser/métodos , Lasers de Gás/uso terapêutico , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Adulto , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento , Adulto JovemRESUMO
Syringocystadenoma papilliferum is a rare benign adnexal skin tumor of apocrine or eccrine glands. We report here an 18-year-old girl who had linear syringocystadenoma papilliferum in the pubic region, which is very rare.