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1.
Acta Obstet Gynecol Scand ; 103(9): 1702-1713, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-38787368

RESUMO

INTRODUCTION: Despite increasing incidence of impacted fetal head at cesarean birth and associated injury, it is unclear which techniques are most effective for prevention and management. A high quality evidence review in accordance with international reporting standards is currently lacking. To address this gap, we aimed to identify, assess, and synthesize studies comparing techniques to prevent or manage impacted fetal head at cesarean birth prior to or at full cervical dilatation. MATERIAL AND METHODS: We searched MEDLINE, Emcare, Embase and Cochrane databases up to 1 January 2023 (PROSPERO: CRD420212750016). Included were randomized controlled trials (any size) and non-randomized comparative studies (n ≥ 30 in each arm) comparing techniques or adjunctive measures to prevent or manage impacted fetal head at cesarean birth. Following screening and data extraction, we assessed risk of bias for individual studies using RoB2 and ROBINS-I, and certainty of evidence using GRADE. We synthesized data using meta-analysis where appropriate, including sensitivity analyses excluding data published in potential predatory journals or at risk of retraction. RESULTS: We identified 24 eligible studies (11 randomized and 13 non-randomized) including 3558 women, that compared vaginal disimpaction, reverse breech extraction, the Patwardhan method and/or the Fetal Pillow®. GRADE certainty of evidence was low or very low for all 96 outcomes across seven reported comparisons. Pooled analysis mostly showed no or equivocal differences in outcomes across comparisons of techniques. Although some maternal outcomes suggested differences between techniques (eg risk ratio of 3.41 [95% CI: 2.50-4.66] for uterine incision extension with vaginal disimpaction vs. reverse breech extraction), these were based on unreliable pooled estimates given very low GRADE certainty and, in some cases, additional risk of bias introduced by data published in potential predatory journals or at risk of retraction. CONCLUSIONS: The current weaknesses in the evidence base mean that no firm recommendations can be made about the superiority of any one impacted fetal head technique over another, indicating that high quality training is needed across the range of techniques. Future studies to improve the evidence base are urgently required, using a standard definition of impacted fetal head, agreed maternal and neonatal outcome sets for impacted fetal head, and internationally recommended reporting standards.


Assuntos
Cesárea , Cabeça , Humanos , Feminino , Gravidez , Feto , Traumatismos do Nascimento/prevenção & controle
2.
BJOG ; 130(1): 70-77, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36052568

RESUMO

OBJECTIVE: To study the impact of shoulder dystocia (SD) simulation training on the management of SD and the incidence of permanent brachial plexus birth injury (BPBI). DESIGN: Retrospective observational study. SETTING: Helsinki University Women's Hospital, Finland. SAMPLE: Deliveries with SD. METHODS: Multi-professional, regular and systematic simulation training for obstetric emergencies began in 2015, and SD was one of the main themes. A study was conducted to assess changes in SD management and the incidence of permanent BPBI. The study period was from 2010 to 2019; years 2010-2014 were considered the pre-training period and years 2015-2019 were considered the post-training period. MAIN OUTCOME MEASURES: The primary outcome measure was the incidence of permanent BPBI after the implementation of systematic simulation training. Changes in the management of SD were also analysed. RESULTS: During the study period, 113 085 vertex deliveries were recorded. The incidence of major SD risk factors (gestational diabetes, induction of labour, vacuum extraction) increased and was significantly higher for each of these factors during the post-training period (p < 0.001). The incidence of SD also increased significantly (0.01% vs 0.3%, p < 0.001) during the study period, but the number of children with permanent BPBI decreased by 55% after the implementation of systematic simulation training (0.05% vs 0.02%, p < 0.001). The most significant change in the management of SD was the increased incidence of successful delivery of the posterior arm. CONCLUSIONS: Systematic simulation-based training of midwives and doctors can translate into improved individual and team performance and can significantly reduce the incidence of permanent BPBI.


Assuntos
Traumatismos do Nascimento , Plexo Braquial , Distocia , Distocia do Ombro , Treinamento por Simulação , Gravidez , Criança , Feminino , Humanos , Distocia do Ombro/epidemiologia , Distocia do Ombro/terapia , Distocia/epidemiologia , Distocia/terapia , Distocia/etiologia , Traumatismos do Nascimento/epidemiologia , Traumatismos do Nascimento/prevenção & controle , Incidência , Plexo Braquial/lesões , Parto Obstétrico/efeitos adversos , Parto Obstétrico/educação , Fatores de Risco , Ombro
3.
Am J Perinatol ; 40(9): 929-936, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-36848935

RESUMO

OBJECTIVE: We estimated the association between diabetes and shoulder dystocia by infant birth weight subgroups (<4,000, 4,000-4,500, and >4,500 g) in an era of prophylactic cesarean delivery for suspected macrosomia. STUDY DESIGN: A secondary analysis from the National Institute of Child Health and Human Development U.S. Consortium for Safe Labor of deliveries at ≥24 weeks with a nonanomalous, singleton fetus with vertex presentation undergoing a trial of labor. The exposure was either pregestational or gestational diabetes compared with no diabetes. The primary outcome was shoulder dystocia and secondarily, birth trauma with a shoulder dystocia. We calculated adjusted risk ratios (aRRs) with modified Poison's regression between diabetes and shoulder dystocia and the number needed to treat (NNT) to prevent a shoulder dystocia with cesarean delivery. RESULTS: Among 167,589 assessed deliveries (6% with diabetes), pregnant individuals with diabetes had a higher risk of shoulder dystocia at birth weight <4,000 g (aRR: 1.95; 95% confidence interval [CI]: 1.66-2.31) and 4,000 to 4,500 g (aRR: 1.57; 95% CI: 1.24-1.99), albeit not significantly at birth weight >4,500 g (aRR: 1.26; 95% CI: 0.87-1.82) versus those without diabetes. The risk of birth trauma with shoulder dystocia was higher with diabetes (aRR: 2.29; 95% CI: 1.54-3.45). The NNT to prevent a shoulder dystocia with diabetes was 11 and 6 at ≥4,000 and >4,500 g, versus without diabetes, 17 and 8 at ≥4,000 and >4,500 g, respectively. CONCLUSION: Diabetes increased the risk of shoulder dystocia, even at lower birth weight thresholds than at which cesarean delivery is currently offered. Guidelines providing the option of cesarean delivery for suspected macrosomia may have decreased the risk of shoulder dystocia at higher birth weights. KEY POINTS: · >Diabetes increased the risk of shoulder dystocia, even at lower birth weight thresholds than at which cesarean delivery is currently offered.. · Cesarean delivery for suspected macrosomia may have decreased the risk of shoulder dystocia at higher birth weights.. · These findings can inform delivery planning for providers and pregnant individuals with diabetes..


Assuntos
Traumatismos do Nascimento , Diabetes Mellitus , Distocia , Trabalho de Parto , Distocia do Ombro , Criança , Feminino , Humanos , Lactente , Recém-Nascido , Gravidez , Traumatismos do Nascimento/epidemiologia , Traumatismos do Nascimento/prevenção & controle , Peso ao Nascer , Distocia/epidemiologia , Distocia/terapia , Macrossomia Fetal/epidemiologia , Macrossomia Fetal/prevenção & controle , Macrossomia Fetal/complicações , Ombro , Distocia do Ombro/epidemiologia
4.
Aust N Z J Obstet Gynaecol ; 63(1): 13-18, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-35587573

RESUMO

BACKGROUND: Vacuum-assisted delivery (VAD) is a common and safe obstetric procedure. However, occasionally serious complications may occur. Clinical guidelines and College Statements have been developed to reduce the risk of serious adverse events. The Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) College Statement C-Obs 16 has not been evaluated to see if advice improves outcomes. AIM: The aim was to evaluate whether compliance with RANZCOG College Statement C-Obs 16 advice reduced the risk of serious adverse outcomes, specifically clinically significant subgaleal haemorrhage and major birth trauma. MATERIALS AND METHODS: Retrospective audit of VADs in a level five hospital (NSW Maternity and Neonatal capability framework) from January 2020 to 2021. RESULTS: There were 1960 women who delivered in the study period, of whom 252 (12.8%) delivered by vacuum, and complete data were available from 241 cases. Statement compliance was observed in 81%. The main deviation from Statement compliance was pulls exceeding three. Statement compliance was associated with a significant reduction in the incidence of subgaleal haemorrhage (0% vs 11%, P = 0.0002), major birth trauma (3% vs 22%, P = 0.0001), requirement for neonatal resuscitation (14% vs 35%, P = 0.0026) and Apgar scores at one minute less than six (5% vs 22% P = 0.0006). Statement compliance was associated with a significant reduction in maternal blood loss at delivery (388 mL vs 438 mL, P = 0.01). Noncompliance with Statement advice was observed significantly more often in pregnancy complicated by gestational diabetes (3% vs 15%, P = 0.02) and birth requiring instrument change (4% vs 13% P = 0.031). CONCLUSION: Compliance with a College Statement is associated with lower rates of subgaleal haemorrhage and major neonatal trauma. The main deviation from compliance was pulls in excess of three. Keyword: birth trauma, clinical guidelines, quality and safety in healthcare, subgaleal haemorrhage, vacuum delivery.


Assuntos
Traumatismos do Nascimento , Vácuo-Extração , Recém-Nascido , Feminino , Humanos , Gravidez , Vácuo-Extração/efeitos adversos , Estudos Retrospectivos , Austrália , Ressuscitação , Traumatismos do Nascimento/epidemiologia , Traumatismos do Nascimento/etiologia , Traumatismos do Nascimento/prevenção & controle , Hemorragia/etiologia , Hematoma/etiologia
5.
Am J Obstet Gynecol ; 225(5): 484.e1-484.e33, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34019885

RESUMO

OBJECTIVE: This study aimed to evaluate the outcomes associated with the implementation of simulation exercises to reduce the sequela of shoulder dystocia. DATA SOURCES: Electronic databases (Ovid MEDLINE, Embase, the Cumulative Index to Nursing and Allied Health Literature database, and Scopus) were initially queried in June 2020 and updated in November 2020. The following 3 concepts were introduced and refined using the controlled vocabulary of the database: vaginal birth, shoulder dystocia, and simulation training. There were no limitations to the year of publication as part of the search strategy. STUDY ELIGIBILITY CRITERIA: We included all studies that reported on the frequency of shoulder dystocia and the associated complications before and after the implementation of interventional exercises to improve outcomes. METHODS: Two authors independently assessed the abstracts and full-text articles of all studies for eligibility and evaluated the quality of the included studies using the Newcastle-Ottawa Scale. Any inconsistencies related to study evaluation or data extraction were resolved by a third author. The coprimary outcomes of this systematic review and meta-analysis were neonatal brachial plexus palsy diagnosed following deliveries complicated by shoulder dystocia and persistence of brachial palsy at 12 months or later. The secondary outcomes were the frequency of shoulder dystocia and cesarean delivery. Study effects were combined using a Bayesian meta-analysis and were reported as risk ratios and 95% credible intervals (Crs). RESULTS: Of the 372 articles reviewed, 16 publications, which included 428,552 deliveries with 217,713 (50.8%) deliveries during the preintervention and 210,839 (49.2%) deliveries during the postinterventional period, were included in the meta-analysis. The incidence of neonatal brachial plexus palsy after shoulder dystocia decreased from 12.1% to 5.7% (risk ratio, 0.37; 95% Cr, 0.26-0.57; probability of reduction 100%). The overall proportion of neonatal brachial plexus palsy decreased, but with less precision, from 0.3% to 0.1% (risk ratio, 0.53; 95% Cr, 0.21-1.26; probability of reduction 94%). Two studies followed newborns with brachial plexus palsy for at least 12 months. One study that reported on persistent neonatal brachial plexus palsy at 12 months among 1148 shoulder dystocia cases noted a reduction in persistent neonatal brachial plexus palsy from 1.9% to 0.2% of shoulder dystocia cases (risk ratio, 0.13; 95% confidence interval, 0.04-0.49). In contrast, the study that reported on persistent neonatal brachial plexus palsy at 12 months for all deliveries noted that it did not change significantly, namely from 0.3 to 0.2 per 1000 births (risk ratio, 0.77; 95% confidence interval, 0.31-1.90). Following the implementation of shoulder dystocia interventional exercises, the diagnosis of shoulder dystocia increased significantly from 1.2% to 1.7% of vaginal deliveries (risk ratio, 1.39; 95% Cr, 1.19-1.65; probability of increase 100%). Compared with the preimplementation period, the cesarean delivery rate increased postimplementation from 21.2% to 25.9% (risk ratio, 1.22; 95% Cr, 0.93-1.59; probability of increase 93%). We created an online tool (https://ccrebm-bell.shinyapps.io/sdmeta/) that permits calculation of the absolute risk reduction and absolute risk increase attributable to the intervention vis-à-vis the incidence of shoulder dystocia, neonatal brachial plexus palsy, and cesarean deliveries. CONCLUSION: Introduction of shoulder dystocia interventional exercises decreased the rate of neonatal brachial plexus palsy per shoulder dystocia case; the data on persistence of neonatal brachial plexus palsy beyond 12 months is limited and contradictory. Implementation of the interventions was associated with an increase in the diagnosis of shoulder dystocia and rate of cesarean deliveries.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Plexo Braquial/lesões , Distocia do Ombro/prevenção & controle , Treinamento por Simulação , Neuropatias do Plexo Braquial/prevenção & controle , Cesárea , Parto Obstétrico , Feminino , Humanos , Gravidez
6.
Am J Obstet Gynecol ; 224(6): 613.e1-613.e10, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33306970

RESUMO

BACKGROUND: One of the controversies in the management of twin gestations relates to mode of delivery, especially when the second twin is in a nonvertex presentation (Vertex/nonVertex pairs) and birth is imminent at extremely low gestation. OBJECTIVE: We hypothesized that, for Vertex/nonVertex twins born before 28 weeks' gestation, cesarean delivery would be associated with a lower risk of adverse neonatal outcomes than trial of vaginal delivery. Our aim was to test this hypothesis by comparing the neonatal outcomes of Vertex/nonVertex twins born before 28 weeks' gestation by mode of delivery using a large national cohort. STUDY DESIGN: This work is a retrospective cohort study of all twin infants born at 240/7 to 276/7 weeks' gestation and admitted to level III neonatal intensive care units participating in the Canadian Neonatal Network (2010-2017). Exposure is defined a trial of vaginal delivery for Vertex/nonVertex twins. Nonexposed (control) groups are defined as cases where both twins were delivered by cesarean delivery, either in vertex or nonvertex presentation (control group 1) or owing to the nonvertex presentation of the first twin (control group 2). Outcome measures are defined as a composite of neonatal death, severe neurologic injury, or birth trauma. RESULTS: A total of 1082 twin infants (541 twin pairs) met the inclusion criteria: 220 Vertex/nonVertex pairs, of which 112 had a trial of vaginal delivery (study group) and 108 had cesarean delivery for both twins (control group 1); 170 pairs with the first twin in nonvertex presentation, all of which were born by cesarean delivery (control group 2); and 151 pairs with both twins in vertex presentation (vertex or nonvertex). In the study group, the rate of urgent cesarean delivery for the second twin was 30%. The rate of the primary outcome in the study group was 42%, which was not significantly different compared with control group 1 (37%; adjusted relative risk, 0.93; 95% confidence interval, 0.71-1.22) or control group 2 (34%; adjusted relative risk, 1.20; 95% confidence interval, 0.92-1.58). The findings remained similar when outcomes were analyzed separately for the first and second twins. CONCLUSION: For preterm Vertex/nonVertex twins born at <28 weeks' gestation, we found no difference in the risk of adverse neonatal outcome between a trial of vaginal delivery and primary cesarean delivery. However, a trial of vaginal delivery was associated with a high rate of urgent cesarean delivery for the second twin.


Assuntos
Traumatismos do Nascimento/etiologia , Apresentação Pélvica/terapia , Parto Obstétrico/métodos , Doenças em Gêmeos/etiologia , Lactente Extremamente Prematuro , Doenças do Prematuro/etiologia , Prova de Trabalho de Parto , Adulto , Traumatismos do Nascimento/mortalidade , Traumatismos do Nascimento/prevenção & controle , Estudos de Casos e Controles , Cesárea , Doenças em Gêmeos/mortalidade , Doenças em Gêmeos/prevenção & controle , Feminino , Humanos , Recém-Nascido , Doenças do Prematuro/mortalidade , Doenças do Prematuro/prevenção & controle , Masculino , Gravidez , Gravidez de Gêmeos , Nascimento Prematuro/terapia , Estudos Retrospectivos , Resultado do Tratamento
7.
Acta Obstet Gynecol Scand ; 100(5): 949-954, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33141937

RESUMO

INTRODUCTION: The fetal pillow has been suggested to reduce maternal trauma and fetal adverse outcomes when used to disimpact the fetal head at full dilatation cesarean section. MATERIAL AND METHODS: We performed a retrospective cohort study of the use of the fetal pillow device at full dilatation cesarean section between September 2014 and March 2018 at Liverpool Women's Hospital, a large UK teaching hospital. RESULTS: There were 471 cases of full dilatation cesarean section during the study period and 391 were included for the analysis; 170 used the fetal pillow and 221 were delivered without. We did not demonstrate any benefit in the significant maternal outcomes of estimated blood loss >1000 mL or >1500 mL, need for blood transfusion, or duration of hospital stay, from the use of the fetal pillow. We did not demonstrate any improvement in fetal outcome following use of the fetal pillow for arterial pH <7.1, Apgar score <7 at 5 minutes or admission to the neonatal unit. For deliveries undertaken at or below the level of the ischial spines there was likewise no benefit from fetal pillow use, except in a reduced risk of an arterial pH <7.1 (relative risk 0.39, 95% CI 0.20-0.80, P = .01); however, admission to the neonatal unit was unaffected. CONCLUSIONS: This is the largest study to date on the use of the fetal pillow at full dilatation cesarean section. We did not demonstrate any statistically significant benefit from the use of the fetal pillow to prevent any maternal or fetal adverse outcomes at full dilatation cesarean section in routine clinical use. Further randomized studies are required to prove clinical benefit from this device before more widespread use.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Cesárea/instrumentação , Primeira Fase do Trabalho de Parto , Segunda Fase do Trabalho de Parto , Adulto , Estudos de Coortes , Feminino , Humanos , Gravidez , Estudos Retrospectivos , Reino Unido/epidemiologia
8.
Acta Obstet Gynecol Scand ; 99(12): 1691-1699, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32609879

RESUMO

INTRODUCTION: Unplanned out-of-hospital deliveries (UOHDs) have earlier been related to higher perinatal mortality and morbidity, but recent research has not paid much attention to them. Our aim was to evaluate the incidence, characteristics, risk factors, and maternal and perinatal mortality and morbidity in UOHDs in Finland. MATERIAL AND METHODS: We conducted a national register study on births, causes of death and congenital anomalies for all live and stillbirths during 1996-2013. The study group included 1420 infants delivered by mothers with UOHDs. The 1 051 139 infants born in hospitals during the study period were the reference group. Data on maternal and delivery characteristics, obstetric procedures, infants' characteristics, neonatal care unit admissions, diagnoses, congenital anomalies and causes of death were collected. RESULTS: The annual rate of UOHDs increased in 1996-2013 from 46 to 260 per 100 000 deliveries, whereas the number of delivery units decreased from 44 to 29. UOHD infants had five times higher perinatal mortality rates than those delivered in hospitals. The perinatal mortality rate did not change by time in the UOHDs, whereas it diminished among in-hospital deliveries. Maternal morbidity in UOHDs was low. The predictors for UOHDs were delivery after the year 2001, delivery in sparsely populated areas, alcohol, drug abuse and/or smoking during pregnancy, being single, fewer prenatal visits, having delivered earlier and birthweight <2500 g. UOHD was one of the predictors of perinatal morbidity and mortality. Among the UOHD cases, the predictors of perinatal morbidity or mortality included low birthweight and preterm delivery. Time period seemed not to predict morbidity or mortality. CONCLUSIONS: The UOHD rate increased, probably due to multifactorial causes, including living in area with low population density and short duration of labor. UOHD was a significant predictor of perinatal morbidity or mortality, but the numbers were very small. Neonatal morbidity and mortality in UOHDs did not seem to be related to the area or time period of birth.


Assuntos
Traumatismos do Nascimento , Entorno do Parto/estatística & dados numéricos , Nascimento Prematuro/epidemiologia , Adulto , Traumatismos do Nascimento/epidemiologia , Traumatismos do Nascimento/etiologia , Traumatismos do Nascimento/prevenção & controle , Causalidade , Feminino , Finlândia/epidemiologia , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Mortalidade Perinatal , Gravidez , Resultado da Gravidez/epidemiologia , Cuidado Pré-Natal/métodos , Cuidado Pré-Natal/estatística & dados numéricos , Fatores de Risco , Natimorto/epidemiologia
9.
Acta Obstet Gynecol Scand ; 99(12): 1710-1716, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32644188

RESUMO

INTRODUCTION: Traction force is a possible risk factor for adverse neonatal outcome in vacuum extraction delivery, but the knowledge is scarce and further investigation is needed. Our hypothesis was that high-level traction force increases the risk of admission to the neonatal intensive care unit. MATERIAL AND METHODS: The study was a hospital-based prospective cohort study on low- and mid-vacuum extractions at the labor and delivery ward, Karolinska University Hospital, Huddinge, Sweden. Traction forces were measured in 331 women. An electronical handle was used to measure and register traction force. The main exposure variable was high-level traction force (≥75th percentile) during the first three pulls and the primary outcome was admission to the neonatal intensive care unit. Logistic regression was used to estimate the adjusted risk. RESULTS: Among the exposed, 14/84 (16.7%) were admitted to neonatal intensive care, and among the unexposed 10/247 (4%). The crude odds ratio (OR) of admission to the neonatal intensive care unit when exposed to high-level traction force was 4.7, and the adjusted (birthweight, gestational length, cup detachment, number of pulls, duration, duration >15 minutes, mid-cavity fetal head station, failed extraction, indication and parity) OR was 2.85 (95% confidence interval [CI] 1.09-7.48). No significant effect was seen in Apgar scores <7 at 5 minutes or pH <7.1. CONCLUSIONS: High-level traction force may be a risk factor for neonatal complications. Although these results do not mandate any alterations in clinical guidelines, perioperative feedback on traction force may be useful to alert the obstetrician to a timely conversion to cesarean section. To study plausible traction force specific outcomes such as head traumas, a larger sample size is required.


Assuntos
Traumatismos do Nascimento , Complicações do Trabalho de Parto , Tração/efeitos adversos , Vácuo-Extração , Adulto , Traumatismos do Nascimento/diagnóstico , Traumatismos do Nascimento/epidemiologia , Traumatismos do Nascimento/etiologia , Traumatismos do Nascimento/prevenção & controle , Cesárea/métodos , Tomada de Decisão Clínica , Feminino , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Complicações do Trabalho de Parto/epidemiologia , Complicações do Trabalho de Parto/etiologia , Complicações do Trabalho de Parto/prevenção & controle , Gravidez , Risco Ajustado/métodos , Fatores de Risco , Suécia/epidemiologia , Tempo para o Tratamento , Tração/métodos , Vácuo-Extração/efeitos adversos , Vácuo-Extração/métodos , Vácuo-Extração/estatística & dados numéricos
10.
J Perinat Neonatal Nurs ; 34(1): 16-26, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31834005

RESUMO

Consumer demand for water birth has grown within an environment of professional controversy. Access to nonpharmacologic pain relief through water immersion is limited within hospital settings across the United States due to concerns over safety. The study is a secondary analysis of prospective observational Perinatal Data Registry (PDR) used by American Association of Birth Center members (AABC PDR). All births occurring between 2012 and 2017 in the community setting (home and birth center) were included in the analysis. Descriptive, correlational, and relative risk statistics were used to compare maternal and neonatal outcomes. Of 26 684 women, those giving birth in water had more favorable outcomes including fewer prolonged first- or second-stage labors, fetal heart rate abnormalities, shoulder dystocias, genital lacerations, episiotomies, hemorrhage, or postpartum transfers. Cord avulsion occurred rarely, but it was more common among water births. Newborns born in water were less likely to require transfer to a higher level of care, be admitted to a neonatal intensive care unit, or experience respiratory complication. Among childbearing women of low medical risk, personal preference should drive utilization of nonpharmacologic care practices including water birth. Both land and water births have similar good outcomes within the community setting.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Salas de Parto , Parto Normal , Complicações do Trabalho de Parto/prevenção & controle , Características de Residência , Adulto , Feminino , Acessibilidade aos Serviços de Saúde , Humanos , Recém-Nascido , Parto Normal/educação , Parto Normal/métodos , Preferência do Paciente , Gravidez , Resultado da Gravidez/epidemiologia , Utilização de Procedimentos e Técnicas , Sistema de Registros/estatística & dados numéricos , Terapia de Relaxamento/métodos , Estresse Psicológico/etiologia , Estresse Psicológico/prevenção & controle , Estados Unidos
12.
Epilepsia ; 59(5): 905-914, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29637551

RESUMO

Among the causes of epilepsy are several that are currently preventable. In this review, we summarize the public health burden of epilepsy arising from such causes and suggest priorities for primary epilepsy prevention. We conducted a systematic review of published epidemiologic studies of epilepsy of 4 preventable etiologic categories-perinatal insults, traumatic brain injury (TBI), central nervous system (CNS) infection, and stroke. Applying consistent criteria, we assessed the quality of each study and extracted data on measures of risk from those with adequate quality ratings, summarizing findings across studies as medians and interquartile ranges. Among higher-quality population-based studies, the median prevalence of active epilepsy across all ages was 11.1 per 1000 population in lower- and middle-income countries (LMIC) and 7.0 per 1000 in high-income countries (HIC). Perinatal brain insults were the largest attributable fraction of preventable etiologies in children, with median estimated fractions of 17% in LMIC and 15% in HIC. Stroke was the most common preventable etiology among older adults with epilepsy, both in LMIC and in HIC, accounting for half or more of all new onset cases. TBI was the attributed cause in nearly 5% of epilepsy cases in HIC and LMIC. CNS infections were a more common attributed cause in LMIC, accounting for about 5% of all epilepsy cases. Among some rural LMIC communities, the median proportion of epilepsy cases attributable to endemic neurocysticercosis was 34%. A large proportion of the overall public health burden of epilepsy is attributable to preventable causes. The attributable fraction for perinatal causes, infections, TBI, and stroke in sum reaches nearly 25% in both LMIC and HIC. Public health interventions addressing maternal and child health care, immunizations, public sanitation, brain injury prevention, and stroke prevention have the potential to significantly reduce the burden of epilepsy.


Assuntos
Epilepsia/prevenção & controle , Prevenção Primária/métodos , Traumatismos do Nascimento/complicações , Traumatismos do Nascimento/prevenção & controle , Lesões Encefálicas Traumáticas/complicações , Lesões Encefálicas Traumáticas/prevenção & controle , Infecções do Sistema Nervoso Central/complicações , Infecções do Sistema Nervoso Central/prevenção & controle , Epilepsia/etiologia , Humanos , Acidente Vascular Cerebral/complicações , Acidente Vascular Cerebral/prevenção & controle
13.
Z Geburtshilfe Neonatol ; 222(1): 25-27, 2018 02.
Artigo em Alemão | MEDLINE | ID: mdl-29499582

RESUMO

The correct placement of the vacuum cup is essential to reduce both maternal and neonatal morbidity after a vacuum-assisted vaginal delivery. Therefore, a checklist based report with all relevant clinical findings and a photo of the infant's head with the location of vacuum tag was introduced to make the exact application of the cup reproducible for. training/instruction purpose.


Assuntos
Documentação/métodos , Fotografação , Vácuo-Extração/educação , Índice de Apgar , Traumatismos do Nascimento/prevenção & controle , Lista de Checagem , Feminino , Humanos , Recém-Nascido , Gravidez , Reprodutibilidade dos Testes
15.
J Pineal Res ; 63(4)2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28776755

RESUMO

Preterm birth is a major contributor to early and delayed physical and cognitive impairment. Epidemiological and experimental data indicate that maternal infections are a significant and preventable cause of preterm birth. Recently, melatonin has been suggested to exert neuroprotective effects in several models of brain injury. Here, we sought to investigate whether the administration of melatonin is able to prevent lipopolysaccharide (LPS)-induced fetal brain damage in a model of LPS-induced preterm labor. For this purpose, 15-day pregnant BALB/c mice received intraperitoneally 2 doses of LPS or vehicle: the first one at 10:00 hours (0.26 mg/kg) and the second at 13:00 hours (0.52 mg/kg). On day 14 of pregnancy, a group of mice was subcutaneously implanted with a pellet of 25 mg melatonin. This experimental protocol resulted in 100% of preterm birth and pup death in the LPS group and a 50% of term birth and pup survival in the melatonin + LPS group. In the absence of melatonin, fetuses from LPS-treated mothers showed histological signs of brain damage, microglial/macrophage activation, and higher levels of IL-1ß, inducible nitric oxide synthase (NOS), and neuronal NOS mRNAs as well as increased histone acetyltransferase activity and histone H3 hyperacetylation. In contrast, antenatal administration of melatonin prevented LPS-induced fetal brain damage. Moreover, when behavioral traits were analyzed in the offspring from control, melatonin, and melatonin + LPS, no significant differences were found, suggesting that melatonin prevented LPS-induced long-term neurodevelopmental impairments. Collectively, our results suggest that melatonin could be a new therapeutic tool to prevent fetal brain damage and its long-term consequences induced by maternal inflammation.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Lesões Encefálicas/prevenção & controle , Melatonina/farmacologia , Fármacos Neuroprotetores/farmacologia , Nascimento Prematuro , Animais , Traumatismos do Nascimento/etiologia , Lesões Encefálicas/etiologia , Feminino , Inflamação/induzido quimicamente , Lipopolissacarídeos/toxicidade , Camundongos , Camundongos Endogâmicos BALB C , Trabalho de Parto Prematuro/induzido quimicamente , Gravidez , Nascimento Prematuro/induzido quimicamente
16.
Med J Aust ; 206(4): 181-185, 2017 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-28253469

RESUMO

It has been 30 years since the World Health Organization first recommended a "maximum" caesarean section (CS) rate of 15%. There are demographic differences across the 194 WHO member countries; recent analyses suggest the optimal global CS rate is almost 20%. Attempts to reduce CS rates in developed countries have not worked. The strongest predictor of caesarean delivery for the first birth of "low risk" women appears to be maternal age; a factor that continues to increase. Most women whose first baby is born by caesarean delivery will have all subsequent children by caesarean delivery. Outcomes that informed the WHO recommendation primarily relate to maternal and perinatal mortality, which are easy to measure. Longer term outcomes, such as pelvic organ prolapse and urinary incontinence, are closely related to mode of birth, and up to 20% of women will undergo surgery for these conditions. Pelvic floor surgery is typically undertaken for older women who are less fit for surgery. Serious complications such as placenta accreta occur with repeat caesarean deliveries, but the odds only reach statistical significance at the third or subsequent caesarean delivery. However, in Australia, parity is falling, and only 20% of women will have more than two births. We should aim to provide CS to women in need and to continue including women in the conversation about the benefits and disadvantages, both short and long term, of birth by caesarean delivery.


Assuntos
Cesárea/estatística & dados numéricos , Procedimentos Cirúrgicos Eletivos/estatística & dados numéricos , Bem-Estar Materno/estatística & dados numéricos , Austrália , Traumatismos do Nascimento/prevenção & controle , Feminino , Humanos , Avaliação de Resultados em Cuidados de Saúde , Gravidez , Organização Mundial da Saúde
17.
Am J Perinatol ; 34(8): 765-773, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28142153

RESUMO

Objective The objective of this study is to determine the maternal and neonatal morbidity associated with attempting operative vaginal delivery (OVD) compared with the alternative of a laboring repeat cesarean delivery (LRCD) in women attempting a trial of labor after cesarean delivery (TOLAC). Methods This is a secondary analysis of a multicenter prospective study designed to assess perinatal outcomes of OVD in women with a prior uterine scar. The study includes women who attempted TOLAC and reached +2 station with a fully dilated cervix. Composites on neonatal and maternal morbidity were compared between women in whom OVD was attempted and those who underwent LRCD by fitting multivariate logistic regression models. Results In total, 6,489 women attempting TOLAC reached 2+ station with a fully dilated cervix. Of these, 5,640 (86.9%) had a spontaneous vaginal delivery, 762 (11.7%) underwent attempted OVD, and 87 (1.3%) had an LRCD. Compared with attempting OVD, LRCD was associated with greater neonatal morbidity (odds ratio [OR]: 2.41; 95% confidence interval [CI]: 1.13-5.15) and less maternal morbidity (OR: 0.28; 95% CI: 0.14-0.55). Maternal morbidity of OVD is driven by perineal injury. Conclusion In laboring women with a previous uterine scar, attempting OVD is associated with greater maternal and less neonatal morbidity than LRCD.


Assuntos
Traumatismos do Nascimento , Parto Obstétrico , Complicações do Trabalho de Parto , Períneo/lesões , Útero , Nascimento Vaginal Após Cesárea , Adulto , Traumatismos do Nascimento/etiologia , Traumatismos do Nascimento/prevenção & controle , Cicatriz/etiologia , Cicatriz/fisiopatologia , Parto Obstétrico/efeitos adversos , Parto Obstétrico/métodos , Parto Obstétrico/estatística & dados numéricos , Feminino , Humanos , Recém-Nascido , New York/epidemiologia , Complicações do Trabalho de Parto/etiologia , Complicações do Trabalho de Parto/fisiopatologia , Complicações do Trabalho de Parto/prevenção & controle , Gravidez , Resultado da Gravidez/epidemiologia , Estudos Prospectivos , Útero/patologia , Útero/fisiopatologia , Nascimento Vaginal Após Cesárea/efeitos adversos , Nascimento Vaginal Após Cesárea/métodos , Nascimento Vaginal Após Cesárea/estatística & dados numéricos
18.
Br J Nurs ; 26(8): 474-475, 2017 Apr 27.
Artigo em Inglês | MEDLINE | ID: mdl-28453320

RESUMO

John Tingle, Reader in Health Law at Nottingham Trent University, discusses proposals for the introduction of a Rapid Resolution and Redress Scheme for families affected by severe avoidable birth injury.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Compensação e Reparação/legislação & jurisprudência , Imperícia/legislação & jurisprudência , Medicina Estatal/legislação & jurisprudência , Humanos , Medicina Estatal/organização & administração , Reino Unido
19.
BJOG ; 123(1): 49-57, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26234485

RESUMO

BACKGROUND: The mode of delivery in term singleton breech presentation has been debated for more than half a century and has been examined in both randomised and observational studies. OBJECTIVE: To determine the absolute and relative risks of perinatal mortality and morbidity in planned vaginal breech delivery. SEARCH STRATEGY: A computer-based literature search was conducted mainly in the databases of HINARI, PubMed and Google scholar for studies comparing planned vaginal delivery and planned caesarean section. SELECTION CRITERIA: Studies that assessed the perinatal mortality and morbidity in relation to the term singleton breech mode of delivery between 1993 and 2014 were included. DATA COLLECTION AND ANALYSIS: In this meta-analysis, 27 articles with a total sample size of 258 953 women were included. Relative and absolute risks of perinatal mortality and morbidity in relation to mode of delivery were determined. MAIN RESULTS: The relative risk of perinatal mortality and morbidity was about two- to five-fold higher in the planned vaginal than in the planned caesarean delivery group. The absolute risks of perinatal mortality, fetal neurologic morbidity, birth trauma, 5-minute Apgar score <7 and neonatal asphyxia in the planned vaginal delivery group were 0.3, 0.7, 0.7, 2.4 and 3.3%, respectively. CONCLUSION: Perinatal mortality and morbidity in the planned vaginal breech delivery were significantly higher than with planned caesarean delivery. Even taking into account the relatively low absolute risks of vaginal breech delivery, the current study substantiates the practice of individualised decision-making on the route of delivery in a term breech presentation. TWEETABLE ABSTRACT: Although vaginal breech delivery is controversial, this review has shown low absolute risk.


Assuntos
Neuropatias do Plexo Braquial/prevenção & controle , Apresentação Pélvica/cirurgia , Cesárea , Parto Obstétrico , Procedimentos Cirúrgicos Eletivos , Adulto , Traumatismos do Nascimento/prevenção & controle , Tomada de Decisões , Feminino , Humanos , Recém-Nascido , Estudos Observacionais como Assunto , Mortalidade Perinatal , Gravidez , Ensaios Clínicos Controlados Aleatórios como Assunto , Nascimento a Termo
20.
BJOG ; 123(1): 111-8, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25688719

RESUMO

OBJECTIVE: To investigate management and outcomes of incidences of shoulder dystocia in the 12 years following the introduction of an obstetric emergencies training programme. DESIGN: Interrupted time-series study comparing management and neonatal outcome of births complicated by shoulder dystocia over three 4-year periods: (i) Pre-training (1996-99), (ii) Early training (2001-04), and (iii) Late training (2009-12). SETTING: Southmead Hospital, Bristol, UK, with approximately 6000 births per annum. POPULATION: Infants and their mothers who experienced shoulder dystocia. METHOD: A bi-monthly multi-professional 1-day intrapartum emergencies training course, that included a 30-minute practical session on shoulder dystocia management, commenced in 2000. MAIN OUTCOMES: Neonatal morbidity (brachial plexus injury, humeral fracture, clavicular fracture, 5-minute Apgar score <7) and documented management of shoulder dystocia (resolution manoeuvres performed, traction applied, head-to-body delivery interval). RESULTS: Compliance with national guidance improved with continued training. At least one recognised resolution manoeuvre was used in 99.8% (561/562) of cases of shoulder dystocia in the late training period, demonstrating a continued improvement from 46.3% (150/324, P < 0.001) pre-training, and 92% (241/262, P < 0.001) in the early training period. In parallel there was reduction in the brachial plexus injury at birth (24/324 [7.4%, P < 0.01], pre-training, 6/262 [2.3%] early training, and 7/562 [1.3%] late training. CONCLUSIONS: There are significant benefits to long-term, embedded training programmes with improvements in both management and outcomes. A decade after the introduction of training there were no cases of brachial plexus injury lasting over 12 months in 562 cases of shoulder dystocia.


Assuntos
Traumatismos do Nascimento/prevenção & controle , Parto Obstétrico/educação , Distocia/prevenção & controle , Educação Médica Continuada , Medicina de Emergência/educação , Obstetrícia/educação , Adulto , Plexo Braquial/lesões , Parto Obstétrico/métodos , Medicina Baseada em Evidências , Feminino , Fidelidade a Diretrizes , Humanos , Recém-Nascido , Análise de Séries Temporais Interrompida , Guias de Prática Clínica como Assunto , Gravidez , Lesões do Ombro , Reino Unido
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