Epidemiological and TNFα polymorphism evaluation in patients with cryptococcal meningitis treated at a referral hospital in North Brazil
Diniz, Alena Mileo Monteiro; Feio, Danielle Cristinne Azevedo; Silva, Aniel de Sarom Negrão; Burbano, Rommel Rodríguez; Lima, Patrícia Danielle Lima de.
Rev. Soc. Bras. Med. Trop
; 52: e20180376, 2019. tab, graf
Artigo
em Inglês
| LILACS | ID: biblio-1041562
Abstract
INTRODUCTION:
The present study evaluated the epidemiology of cryptococcal meningitis and TNFα gene polymorphisms in patients at a reference hospital in northern Brazil.METHODS:
Samples from 25 patients infected with Cryptococcus spp. were collected to confirm the infection and to analyze the TNFα gene polymorphisms.RESULTS:
Cryptococcus neoformans was detected as the predominant etiological agent (100%) in HIV-positive patients. No genetic polymorphic changes were found.CONCLUSIONS:
No correlation was observed between the analyzed TNFα polymorphisms and cryptococcal meningitis.
Biblioteca responsável:
BR1.1
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