Lymphocytic thrombophilic arteritis with lower-limb ulcers
An. bras. dermatol
; 96(3): 315-318, May-June 2021. graf
Article
em En
| LILACS
| ID: biblio-1285056
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Lymphocytic thrombophilic arteritis is a recently described entity, histopathologically characterized by lymphocytic vasculitis that affects the arterioles of the dermo-hypodermic junction, associated with deposition of fibrin and a luminal fibrin ring. A 49-year-old female patient presented with achromic maculae and a well-defined ulcer on the medial aspect of the left lower limb. The biopsy showed intense inflammatory infiltrate in the papillary dermis with a predominance of lymphocytes, and medium-caliber vessels surrounded by mononuclear infiltrates in the deep reticular dermis. Masson's trichrome staining showed intense destruction of the muscle layer of the vascular wall and a fibrin ring. Good clinical response was attained with azathioprine. The authors believe that the ulceration might be another clinical presentation or represent an atypical progression of this condition.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Arterite
/
Úlcera da Perna
Limite:
Female
/
Humans
Idioma:
En
Revista:
An. bras. dermatol
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil