Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
J. venom. anim. toxins incl. trop. dis
; 19: 1-7, maio 2013.
Article
em En
| LILACS, VETINDEX
| ID: biblio-1484532
Biblioteca responsável:
BR1.1
Localização: BR68.1
ABSTRACT
The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil. Findings A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p< 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI 0.1-0.3) and anti-HBc alone was 2.85% (95% CI 2.5-3.2). Conclusions There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age (p< 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 (p< 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
/
VETINDEX
Assunto principal:
Sorologia
/
Virologia
/
Hepatite B
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Animals
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
J. venom. anim. toxins incl. trop. dis
Assunto da revista:
TOXICOLOGIA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Brasil