Evaluation of antibacterial activity of medicinal plants in popular medicine: Alternanthera brasiliana (penicillin), Plantago major (broadleaf plantain), Arctostaphylos uva-ursi (bearberry), and Phyllanthus niruri (stone breaker)/Avaliação da atividade antibacteriana de plantas medicinais de uso popular: Alternanthera brasiliana (penicilina), Plantago major (tansagem), Arctostaphylos uva-ursi (uva-ursi) e Phyllanthus niruri (quebra-pedra)
Artigo
em Português
| Instituto Evandro Chagas (SOPHIA) | ID: iec-20766
Os estudos de substâncias obtidas de vegetais vêm adquirindo novas perspectivas, em razão dos problemas associados à terapêutica de diversas infecções, principalmente no que diz respeito à resistência aos antimicrobianos.
OBJETIVOS:
Avaliar a atividade antibacteriana de plantas medicinais, frente a diferentes espécies de bactérias, bem como analisar seus perfis cromatográficos.
A fração acetato de etila de A. uva-ursi apresentou CIM de 125 µg/mL contra M. genitalium e de 31,25 µg/mL contra S. aureus, sendo essa última uma atividade antibacteriana excelente. Para a mesma fração, P. niruri apresentou atividade antibacteriana moderada, com valores de CIM de 250 µg/mL contra M. genitalium e S. aureus. As espécies A. brasiliana e P. major apresentaram fraca ou nenhuma atividade contras as cepas testadas.
Studies of substances obtained from vegetables have been acquiring new perspectives, due to problems associated with the treatment of several infections, mainly about the resistance to antimicrobials.
OBJECTIVES:
To evaluate the antibacterial activity of medicinal plants against different species of bacteria, as well as to analyze their chromatographic profiles. MATERIALS AND
The ethyl acetate fraction of A. uva-ursi presented MIC of 125 µg/mL against M. genitalium and 31.25 µg/mL against S. aureus, the latter has been an excellent antibacterial activity. For the same fraction, P. niruri showed moderate antibacterial activity, with MIC of 250 µg/mL against M. genitalium and S. aureus. The species A. brasiliana and P. major showed little or no activity against the tested strains.
CONCLUSION:
It was not possible to determine a close link between popular medicine, in vitro antibacterial activity, and the phytochemical profile of plants, since the antibacterial effects of the studied plant species have varied compared to different bacteria with and without cell walls.