Seropositivity and risk factors associated with Toxoplasma gondii infection in patients treated at the Municipal Laboratory of Oriximiná, Pará State, Brazil/Soropositividade e fatores de risco associados à infecção por Toxoplasma gondii em pacientes atendidos no Laboratório Municipal de Oriximiná, estado do Pará, Brasil
Foi evidenciada a elevada frequência de pacientes soropositivos para T. gondii atendidos no Laboratório Municipal de Oriximiná, bem como a falta de concordância em 100% entre RIFI e ELISA, demonstrando-se a necessidade de se utilizar mais de uma técnica laboratorial para a detecção de anticorpos anti-T. gondii.
A total of 521 samples were collected. The frequency of seropositive individuals with T. gondii was 68.7%. In 51%, only IgGantibodies were found, while in 17.7% IgG/IgMantibodies were detected, a profile compatible with acute infection. Almost perfect agreement between ELISA and IFAT tests was found regarding the IgG (Kappa = 0.84). In univariate analysis, the variables significantly associated with positivity for T. gondii were age group, consumption of greens and vegetables, previous positive result, abortion, and presence of cat in the house. As for the logistic regression, it was identified that a higher age group, the presence of cats as pets, and a lower income range were factors that presented a higher risk of infection by T. gondii.
CONCLUSION:
The high frequency of T. gondii seropositive patients seen at the Municipal Laboratory of Oriximiná was evidenced, as well as a lack of perfect agreement between IFAT and ELISA, demonstrating the need to use more than one laboratorytechnique for the detection of anti-T. gondii antibodies.