Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil
Melo Junior, Aristides Bezerra de; Souza, William Marciel de; Acrani, Gustavo Olszanski; Carvalho, Valéria Lima; Romeiro, Marilia Farignoli; Tolardo, Aline Lavado; Silva, Sandro Patroca da; Cardoso, Jedson Ferreira; Chiang, Jannifer Oliveira; Vianez Júnior, João Lídio da Silva Gonçalves; Azevedo, Raimunda do Socorro da Silva; Figueiredo, Luiz Tadeu Moraes; Vasconcelos, Pedro Fernando da Costa; Nunes, Márcio Roberto Teixeira; Medeiros, Daniele Barbosa de Almeida.
MELO JUNIOR, Aristides Bezerra de et al. Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil. Infection, Genetics and Evolution, v. 60, p. 71-76, June 2018. DOI: https://doi.org/10.1016/j.meegid.2018.02.027.
Artigo
em Inglês
| Instituto Evandro Chagas (DSpace) | ID: ied-3066
Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by acute febrile illness with myalgia and arthralgia lasting three to five days. However, the genomic and evolutionary aspect of this virus has not been elucidated. In this study, we described the complete coding sequences of three segments of two TCMV strains isolated in Brazil and three complete coding sequences of the small segment of three TCMV strains. All the strains sequenced in this study showed the typical genomic organization of orthobunyaviruses that infect vertebrates, except for the absence of the open reading frame that encodes the well-described non-structural small protein. This study presents the genomic and evolutionary characterization of TCMV strains and would be helpful for diagnostic purposes and epidemiology. / This study was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (Grants 302987/2008-8, 302584/2015-3 - MRTN; 457664/2013-4, 303999/2016-0-PFCV; 306581/2016-7-DBAM) and Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil (Grant 14/02438-6-LTMF; Scholarships No. 12/24150-9 and 17/13981-0 -WMS; 14/20851-8-MFR; 16/17457-1-ALT).
Texto completo
Documentos relacionados