Hepatotoxicidad por amoxicilina/ácido clavulánico: caso clínico / Hepatotoxixity associated to the use of amoxicillin clavulanic acid
Rev. méd. Chile
; 127(12): 1487-91, dic. 1999. ilus, graf
Article
em Es
| LILACS
| ID: lil-258074
Biblioteca responsável:
CL1.1
ABSTRACT
We report a 72 years old diabetic male that, after the use of combined amoxicillin-clavulanic acid, developed pruritus and jaundice. Liver function tests showed serum total bilirubin of 4.3 mg/dL aspartate aminotransferase 140 U/l (normal <35 U/L), alanine aminotransferase 470 U/L (normal <40) and alkaline phosphatases of 400 U/L (normal <100). Serology for hepatitis A, B and C viruses was negative, ERCP showed a normal biliary tree and liver biopsy disclosed a cholestatic hepatitis. Ursodeoxycholic was started to relieve pruritus. Liver function tests improved shortly thereafter, suggesting that this drug may be useful in the treatment of drug induced cholestasis
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Ácido Clavulânico
/
Doença Hepática Induzida por Substâncias e Drogas
/
Amoxicilina
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Chile