The Acre Project: the epidemiology of malaria and arthropod-borne virus infections in a rural Amazonian population
Silva-Nunes, Mônica da; Malafronte, Rosely dos Santos; Luz, Bruna de Almeida; Souza, Estéfano Alves de; Martins, Lívia Carício; Rodrigues, Sueli Guerreiro; Chiang, Jannifer Oliveira; Vasconcelos, Pedro Fernando da Costa; Muniz, Pascoal Torres; Ferreira, Marcelo Urbano.
Cad. saúde pública
; 22(6): 1325-1334, jun. 2006. mapas, tab
Artigo
em Inglês
| LILACS | ID: lil-428313
The authors describe the baseline malaria prevalence and arbovirus seroprevalence among 467 subjects in an ongoing cohort study in rural Amazonia. Most subjects (72.2 percent) reported one or more previous episodes of malaria, and 15.6 percent had been hospitalized for malaria, but only 3.6 percent of individuals five years or older had malaria parasites detected by microscopy (10 with Plasmodium vivax and 4 with P. falciparum). Antibodies to Alphavirus, Orthobunyavirus, and/or Flavivirus were detected by hemagglutination inhibition (HI) in 42.6 percent of subjects aged five years or older, with a higher seropositivity rate among males (49.2 percent) than females (36.2 percent). Since 98.9 percent of subjects had been immunized for yellow fever, the presence of cross-reactive antibodies to dengue and other Flaviviruses cannot be ruled out, but at least 12 subjects (3.3 percent) with IgM antibodies to dengue virus detected by ELISA had a putative recent exposure to this virus.
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