An aqueous extract of guaraná (Paullinia cupana) decreases platelet thromboxane synthesis
Braz. j. med. biol. res
; 24(4): 421-4, 1991. tab
Article
em En
| LILACS
| ID: lil-99472
Biblioteca responsável:
BR26.1
ABSTRACT
The effects of an aqueous extract of guaraná (Paullinia cupana) on rabbit platelet aggregation and thromboxane synthesis were examined. The guaraná extract (100 mg/ml) and fractions separated by TLC (origin and xanthines) decreased platelet aggregation (37.27 and 31% of control values, respectively) and platelet thromboxane formation from [14C]-arachidonic acid (78, 70 and 50% of control values respectively). The decreased thromboxane synthesis could be responsible, at least in part, for the antiaggregatory action of guaraná
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Base de dados:
LILACS
Assunto principal:
Plantas Medicinais
/
Inibidores da Agregação Plaquetária
/
Extratos Vegetais
/
Tromboxanos
Limite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1991
Tipo de documento:
Article