Tonometry to estimate intestinal perfusion in newborn piglets.
Arch Dis Child Fetal Neonatal Ed
; 81(2): F105-9, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10448177
ABSTRACT
AIM:
To determine the correlation between gastric intramucosal pH and superior mesenteric artery (SMA) flow in newborn piglets.METHODS:
Fourteen newborn piglets were randomly assigned to either a control or to an epinephrine group which received 0,1,2,4,0 microg/kg/min of epinephrine for 60 minutes, each dose. Gastric tonometry was performed, SMA flow was measured, and intramucosal pH and the ratio of tonometer pCO(2) over arterial pCO(2) (rCO(2)) were calculated.RESULTS:
Intramucosal pH decreased over time in both groups, but tended to be lower in the epinephrine group. With increasing dose of epinephrine, SMA flow decreased; this in turn increased rCO(2) (p = 0.04) with a tendency to decrease intramucosal pH (p = 0.06).CONCLUSIONS:
Gastric tonometry may be useful in human neonates to evaluate gut ischaemia.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artéria Mesentérica Superior
/
Determinação da Acidez Gástrica
Limite:
Animals
Idioma:
En
Revista:
Arch Dis Child Fetal Neonatal Ed
Assunto da revista:
PEDIATRIA
/
PERINATOLOGIA
Ano de publicação:
1999
Tipo de documento:
Article