Prevalence of coeliac disease in Turner syndrome.
Acta Paediatr
; 88(9): 933-6, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10519331
ABSTRACT
This study was undertaken to investigate the prevalence of coeliac disease in children and adolescents with Turner syndrome. Eighty-seven children and adolescents with Turner syndrome were screened for IgA-antiendomysium antibodies (EMA) and IgA-antigliadin antibodies (AGA), 5% (4/87) being found to be EMA-positive, and 15% (13/87) to have AGA levels above normal. Of the 10 patients who were either AGA- or EMA-positive and further investigated with intestinal biopsy, four manifested villous atrophy (i.e. all three of the EMA-positive patients, but only one of the seven AGA-positive patients). The results suggest EMA-positivity to be a good immunological marker for use in screening for coeliac disease, and such screening to be justified in patients with Turner syndrome.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Turner
/
Imunoglobulina A
/
Doença Celíaca
/
Anticorpos Anti-Idiotípicos
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Female
/
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Acta Paediatr
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Suécia