Hemophagocytic syndrome in pregnancy.
Obstet Gynecol
; 95(6 Pt 2): 1022-4, 2000 Jun.
Article
em En
| MEDLINE
| ID: mdl-10808012
ABSTRACT
BACKGROUND:
Hemophagocytic syndrome is characterized by nonmalignant histiocytes that undergo uncontrolled phagocytosis of normal hematopoietic cells. Clinical severity ranges from complete recovery to rapid deterioration and death. CASE Thrombocytopenia was discovered upon routine initial prenatal evaluation of a 24-year-old, gravida 2, para 1, at 29 weeks' gestation with a history of necrotizing lymphadenitis. Cytopenia and elevated transaminases developed, followed by hyperpyrexia. The patient delivered and her postpartum course was complicated by coagulopathy, multiorgan failure, and death. Bone marrow biopsy confirmed hemophagocytic syndrome.CONCLUSION:
Early diagnosis of hemophagocytic syndrome during pregnancy might be helped by recognizing symptoms and signs, including a history of necrotizing lymphadenitis, and obtaining a bone marrow biopsy.
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Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Histiocitose de Células não Langerhans
Tipo de estudo:
Screening_studies
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Obstet Gynecol
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos